PURPOSE: The aim of this paper is to identify initial barriers influencing implementation of supported employment (SE). SE, according to the individual placement and support (IPS) approach, has been recognised as an evidence-based method to help people with severe mental illness to find regular employment. DESIGN/METHODOLOGY/APPROACH: A systematic implementation evaluation of the first randomised

Intestinal ischemia as well as mastocytosis occur in patients with inflammatory bowel disease and irritable bowel syndrome. Our aim was to clarify how ischemia with reperfusion (I/R) affects the structure, enteric neurons, and immune cells in the colon. Rats were subjected to colon ischemia for 1 h and reperfused for 1 day up to 20 weeks; sham-operated rats were used as controls. No structural rem

ABSTRACT: After severe tissue injury, innate immunity mounts a robust systemic inflammatory response. However, little is known about the immediate impact of multiple trauma on early complement function in humans. In the present study we hypothesized that multiple trauma results in immediate activation, consumption and dysfunction of the complement cascade and that the resulting severe "complemento

Alterations in the expression and signalling pathways of vascular endothelial growth factor (VEGF) have been linked to the clinical features and pathogenesis of hematologic malignancies. In this study, we showed that VEGF protein expression was statistically significantly higher in the leukemic blasts than in the normal hematopoietic counterparts. A statistically significant correlation between ex

OBJECTIVE: Regular blood pressure control has been advocated for early detection and treatment of patients with hypertension. We aimed to study whether long-term survival rate is related to socioeconomic circumstances and biological factors among middle-aged men with screened new hypertension. METHODS: Of the 22 444 men who attended a general health examination in Malmo, Sweden during 1974-1984, i

The present paper concerns a performance-based fire safety analysis and design of a high-rise building. The resulting fire safety recommendations are compared with those specified by acceptable solutions in terms of the earlier prescriptive building code. The respective risk to life resulting from the analysis is compared and discussed. The benefit and need of using a risk based verification metho

Walking difficulties are common in neurological and other disorders, as well as among the elderly. There is a need for reliable and valid instruments for measuring walking difficulties in everyday life since existing gait tests are clinician rated and focus on situation specific capacity. The Walk-12G was adapted from the 12-item multiple sclerosis walking scale as a generic patient-reported ratin

BACKGROUND: The blood group antigens S and s are defined by amino acids Met or Thr at position 29, respectively, on glycophorin B (GPB). Commercial anti-s reagents are expensive to produce because of the scarcity of human anti-s serum. Our aim was to develop hybridoma cell lines that secrete reagent-grade anti-s monoclonal antibodies (MoAbs) to supplement the supply of human anti-s reagents. STUDY

Economies in transition (EiTs) (e. g. Ukraine (UA), Belarus, Moldova, etc.) are signifi cantly dependent on energy imports, and require revitalization of their agricultural sectors and improvements in the state of the environment. Development of national bioenergy potentials can contribute to the solutions to these problems. However, EiTs face technical, political, fi nancial, and capacity-based c

In efforts to find synergies or trade-offs between the environmental and social pillars of policies aimed at sustainable development, a key set of issues are often discussed in terms of geographical scale. The aim of this paper is to critically examine the framings of social and environmental sustainability challenges as scale-related (such as local - global or North-South) involved in processes i