BACKGROUND: Kinetic energy (KE) of intracardiac blood flow reflects myocardial work spent on accelerating blood and provides a mechanistic window into diastolic filling dynamics. Diastolic dysfunction may represent an early stage in the development of heart failure (HF). Here we evaluated the hemodynamic effects of impaired diastolic function in subjects with and without HF, testing the hypothesis

The present manuscript assesses the rhetorical claims made by authors in a selected corpus of CCT articles (2005-2019) in three representative journals. Against the widespread mantras of “theoretical contributions”, it offers a humble, pluralist framework for CCT scholars to shape and develop relevant and impactful research contributions.

In this research we explored consumer acculturation by examining Muslim immigrants’ negotiation of market-mediated progressive gender ideologies by studying Bangladeshi migrant consumers in Sweden. Our findings discerned various logics in the general critique and discursive resistance against commodification of market-mediated gender progressive “inclusivity”.

Background: Reducing the need for hospitalisation in patients with chronic obstructive pulmonary disease (COPD) is an important goal in COPD management. The aim of this study was to evaluate re-hospitalisation, treatment, comorbidities and mortality in patients with COPD who were hospitalised for the first time due to a COPD exacerbation. Methods: This was a retrospective, population-based observa

Background: Little information is available on the official postgraduate and subspecialty training programs in movement disorders (MD) in Europe and North Africa. Objective: To survey the accessible MD clinical training in these regions. Methods: We designed a survey on clinical training in MD in different medical fields, at postgraduate and specialized levels. We assessed the characteristics of t

Tumor-associated macrophages (TAMs) continuously fine tune their immune modulatory properties, but how gene expression programs coordinate this immune cell plasticity is largely unknown. Selective mRNA translation, controlled by MNK1/MNK2 and mTOR pathways impinging on eIF4E, facilitates reshaping of proteomes without changes in abundance of corresponding mRNAs. Using polysome profiling developed

Resveratrol is a photosensitive, bioactive molecule which has received increasing research interest during the past decade for its antioxidant properties. However, it has low solubility in water or common triglyceride oils. Resveratrol solubilization in oil can only be achieved in essential oils, such as flavour oils, but the stability of emulsions produced with this type of oils is low as they ar

The forthcoming Laser Interferometer Space Antenna (LISA) will probe the population of coalescing massive black hole (MBH) binaries up to the onset of structure formation. Here, we simulate the galactic-scale pairing of ∼106 M☉ MBHs in a typical, non-clumpy main-sequence galaxy embedded in a cosmological environment at z = 7-6. In order to increase our statistical sample, we adopt a strategy that

A new modification of a table-Top laser-driven water-jet plasma X-ray source has been successfully implemented and commissioned at the Extreme Light Infrastructure (ELI) Beamlines user facility. In order to preserve the broadband nature of the source for spectroscopic experiments, a polycapillary lens was initially chosen as the focusing element. Generally, polycapillary X-ray optics have a narrow

BACKGROUND: Injuries were the most common cause of hospitalization in Sweden in 2017. There is a lack of knowledge about trauma recovery and its relation to health-related quality of life (HRQoL) after hospitalization due to minor trauma. This study aimed to prospectively evaluate recovery and HRQoL at discharge from hospital and 3 and 6 months after the trauma. METHODS: This is a secondary analys

When responses to international crimes are managed in terms of post-conflict justice, this event may end 'the demarcation debate' before it has begun, thereby rendering it superfluous among legal scholars. This is to say that the transition from theory to reality arguably has the effect of cancelling any sharp distinction between international criminal law, international human rights law and inter

High throughput approaches such as whole genome sequencing (WGS) and whole exome sequencing (WES) create an unprecedented amount of data providing powerful resources for clinical care and research. Recently, WGS and WES services have been made available by commercial direct-to-consumer (DTC) companies. The DTC offer of genetic testing (GT) has already brought attention to potentially problematic i

We propose a low-scale renormalizable trinification theory that successfully explains the flavor hierarchies and neutrino puzzle in the Standard Model (SM), as well as provides a dark matter candidate and also contains the necessary means for efficient leptogenesis. The proposed theory is based on the trinification SU(3)C×SU(3)L×SU(3)R gauge symmetry, which is supplemented with an additional flavo

The global epidemic of Alzheimer disease (AD) is worsening, and no approved treatment can revert or arrest progression of this disease. AD pathology is characterized by the accumulation of amyloid-β (Aβ) plaques and tau neurofibrillary tangles in the brain. Genetic data, as well as autopsy and neuroimaging studies in patients with AD, indicate that Aβ plaque deposition precedes cortical tau pathol