This doctoral thesis delves into the transformation of the customer journey—that is, the direct and indirect interactions between a customer and retailer over time—in the smartphone era. Using a socio-material perspective, it goes beyond current visions of the customer journey, which often focus on emotions and experiences, and instead explores how agency is distributed across elements that includThis doctoral thesis delves into the transformation of the customer journey—that is, the direct and indirect interactions between a customer and retailer over time—in the smartphone era. Using a socio-material perspective, it goes beyond current visions of the customer journey, which often focus on emotions and experiences, and instead explores how agency is distributed across elements that includ

Elites are often offered prestigious state prizes and awards. Although most elites accept, prestigious prizes constitute a challenge for others since institutional symbolic capital cannot be merely accepted, but requires careful negotiation and management. This article investigates the dilemma of being consecrated by the state by studying civil society elites’ reception and use of royal honours, t

Understanding the factors and mechanisms involved in beta-cell development will guide therapeutic efforts to generate fully functional beta cells for diabetes. Neurogenin 3 (NGN3) is the key transcription factor that marks endocrine progenitors and drives beta-cell differentiation. Here we screen for binding partners of NGN3 and identify the deubiquitylating enzyme USP7 as a key regulator of NGN3

ABSTRACT: After severe tissue injury, innate immunity mounts a robust systemic inflammatory response. However, little is known about the immediate impact of multiple trauma on early complement function in humans. In the present study we hypothesized that multiple trauma results in immediate activation, consumption and dysfunction of the complement cascade and that the resulting severe "complemento

The purpose was to describe physical activity with respect to leisure and working activity in patients operated on by high tibial osteotomy using the hemicallotasis technique for knee osteoarthritis (OA), preoperatively and 10 years postoperatively.

The Kauffman model describes a particularly simple class of random Boolean networks. Despite the simplicity of the model, it exhibits complex behavior and has been suggested as a model for real world network problems. We introduce a novel approach to analyzing attractors in random Boolean networks, and applying it to Kauffman networks we prove that the average number of attractors grows faster tha

OBJECTIVES: We evaluated the prevalence and mechanism of poor responsiveness to clopidogrel and prasugrel in coronary artery disease patients with and without diabetes. BACKGROUND: Low platelet inhibition by clopidogrel is associated with ischemic clinical events. A higher 600-mg loading dose (LD) has been advocated to increase responsiveness to clopidogrel. METHODS: In this study, 110 aspirin-tre

Malunion after a distal radius fracture can be treated with an osteotomy of the distal radius. Autologous iliac crest bone graft is often used to fill the gap, but the procedure is associated with donor site morbidity. In this study a novel fast resorbing biphasic bone substitute consisting of a mixture of calcium sulphate and calcium phosphate is used (Cerament BoneSupport AB, Sweden). Fifteen co

A diffusion model of noninvasive absorption spectroscopy was used to determine how the change in signal resulting from a point absorber depends on the position of that absorber relative to the source and detector. This is equivalent to calculating the relative probability that a photon will visit a certain location in tissue before its detection. Experimental mapping of the point-target response i

This paper compares the performance and the robustness of several linear adaptive controllers using a linear system with time–varying disturbance in the presence of measurement noise. For the purpose of comparison we select the direct and indirect model reference adaptive controller (MRAC), the direct MRAC with σ–modification, and the L1 adaptive controller. Using tools from linear systems theory

This paper explores a strategy of spatial expression which utilizes orientation, a way of describing the spatial relationship of entities by means of reference to their facets. We present detailed data and analysis from two languages, Jahai (Mon-Khmer, Malay Peninsula) and Lavukaleve (Papuan isolate, Solomon Islands), and supporting data from five more languages, to show that the orientation strat