The integrin family of adhesion receptors regulates basic functions of cells, and the signals they induce are altered in tumor cells. In this review we discuss how different integrin-dependent signals are generated during cell adhesion and by physical forces acting on cells. We also describe how reactive oxygen species are integral parts of integrin signaling and highlight a few important question

Farmers as volunteers in research could potentially provide a rich resource for exploring sustainable agricultural research questions. To discern emerging patterns in citizen science-based studies on topics with relevance for sustainable agriculture, and reveal salient challenges and opportunities for conducting such studies, we conducted a systematic literature review of 27 peer-reviewed articles

Mild behavioral impairment (MBI) is suggested as risk marker for neurodegenerative diseases, such as Alzheimer's disease (AD). Recently, pathologic tau deposition in the brain has been shown closely related to clinical manifestations, such as cognitive deficits. Yet, associations between tau pathology and MBI have rarely been investigated. It is further debated if MBI precedes cognitive deficits i

BackgroundIntersectionality theory combined with an analysis of individual heterogeneity and discriminatory accuracy (AIHDA) can facilitate our understanding of health disparities. This enables the application of proportionate universalism for resource allocation in public health. Analyzing self-rated health (SRH) in Sweden, we show how an intersectional perspective allows for a detailed mapping o

Background: With modern therapy, over 90% of Wilms tumor patients can expect to become long-term survivors, and focus on morbidity and late effects become increasingly important. We provide a novel evaluation and insight to subsequent hospitalizations in 5-year survivors of Wilms tumor. Methods: As part of the Adult Life after Childhood Cancer in Scandinavia (ALiCCS) study, we identified 5-year su

This paper draws on artistic explorations of territorial and spatial forces through analysis of projects set in the natural landscape, in a specific indoor site or at the threshold between the two. Specific attention is given to the artistic processes at play in the transformation of materials cre- ated/collected in the natural environment when shaped for presentation in an indoor location. What i

How does the presence of an international institution, the EU, shape the norms and normality, policies and polities of its political environment? This research theme raises questions about both the influence and subjects of the EU — ontologically, epistemologically and methodologically. In terms of influence, the question is how does the EU shape its political environment — what is the form of pow

Awakening interest in anion exchange membrane fuel cells (AEMFC) for low temperature applications has led to an increased demand for high-performing polymers stable under alkaline conditions. In this study a poly(p-terphenylene piperidinium)-based (PAP) membrane and ionomer was synthesised and applied in membrane electrode assemblies (MEAs), with porous gas-diffusion electrodes based on Pt catalys

One type of light source that remains largely unexplored in the field of light transport rendering is the light generated by superluminal particles, a phenomenon more commonly known as Cherenkov radiation. By re-purposing the Frank-Tamm equation for rendering, the energy output of these particles can be estimated and consequently mapped to photons, making it possible to visualize the brilliant blu

Background: Limited information is available regarding intraoperative ventilator settings and the incidence of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgical procedures. The aim of this post-hoc analysis of the 'Multicentre Local ASsessment of VEntilatory management during General Anaesthesia for Surgery' (LAS VEGAS) study was to examine the ventilator settings o

The existing information supports the use of this material as described in this safety assessment. p-Tolualdehyde was evaluated for genotoxicity, repeated dose toxicity, developmental and reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization potential, and environmental safety. Data from read-across analog benzaldehyde (CAS # 100-52-7) show that p-tolualdehyde is not

The increasing fragmentation and the rising number of organizations in society create major challenges when implementing policy. In this article, we propose that the concept of metagovernance is useful when addressing these challenges in the governance of knowledge structures. The enhancement of knowledge structures in the Swedish social services is our study object. Networks at national, regional