Sökresultat

Filtyp

Din sökning på "*" gav 549748 sökträffar

Mother-infant interactions in the lab setting : Collaborative participation frameworks and task orientation

The study discussed in this article aimed to understanding how pre-activity formulations are designed and accomplished by mothers in play interactions as everyday interactional business. Here, we report specifically on instances during the lab-based interactions where the mother orients to the lab-based task of singing with their infant, and discuss potential implications of such participant orien

Mitochondrial iron transporter ClMrs3/4 regulates iron homeostasis to modulate nitric oxide balance facilitating appressorial development in Curvularia lunata

Iron is indispensable for the vast majority of organisms, and iron homeostasis plays a pivotal role in both the physiology and pathogenesis of fungal pathogens. However, the underlying mechanisms by which iron homeostasis modulates fungal pathogenesis remain to be fully elucidated. We therefore focused on investigating the functions of mitochondrial iron transporter ClMrs3/4 in virulence. We condu

Oversampling-Based Control with Multi-Core and Edge Implementations

Digital control systems introduce unavoidable computational latencies. For some controllers this time delay inhibits practical use, even though they in theory could provide more efficient control. For example, solving an optimization problem each sampling period when using model predictive control. By sampling faster than the computation time and executing independent controllers on distributed ha

Clinical Significance of LINC00261 in the Pathogenesis of Pancreatic, Colorectal, Hepatocellular, and Gallbladder Cancer

Pancreatic (PC), colorectal (CRC), hepatocellular (HCC), and gallbladder (GC) cancers together account for nearly 20% of all cancer cases. However, specific biomarkers and therapeutic targets for these cancers are lacking. Diagnosing these cancers early and providing timely, appropriate treatment to improve patient outcomes is crucial. In this context, previous studies, including ours, have highli

Connecting Teachers – Changing from Within : Proceedings from the 2024 Lund University Conference on Teaching and Learning

The 2024 Lund University Conference on Teaching and Learning, hosted by MedCUL and the Division for Higher Education Development (AHU), took place in the newly inaugurated Forum Medicum – an environment purposefully designed to inspire connection, collaboration, and exchange. The venue’s open architecture mirrored the conference theme, Connecting teachers – changing from within, underscoring the r

Managing development choices is essential to reduce coastal flood risk in China

Future exposure to coastal flooding in China is driven more by growing populations and economic activity rather than by rising seas and intensifying storm surges. Policymakers must anticipate these multiple risk drivers to better inform spatial planning and development strategies and to ensure effective, sustainable coastal adaptation.

Investigating late-stage particle production in pp collisions with balance functions

Balance functions have been regarded in the past as a method of investigating the late-stage hadronization found in the presence of a strongly-coupled medium. They are also used to constrain mechanisms of particle production in large and small collision systems. Charge balance functions for inclusive and identified particle pairs are reported as a function of charged particle multiplicity in proto

Where to restore – an approach to spatial prioritization of connectivity forests for forest landscape restoration

With two centuries of forestry, natural forests in boreal Swedenare rare and strongly fragmented. Hence, restoration aiming toimprove conditions for forest biodiversity is needed. However,to ensure landscape connectivity – where to restore is a criticalconcern.Our study objective was to identify connectivity forest thatthrough restoration support connectivity and biodiversity. Thestudy area coversWith two centuries of forestry, natural forests in boreal Sweden are rare and strongly fragmented. Hence, restoration aiming to improve conditions for forest biodiversity is needed. However, to ensure landscape connectivity – where to restore is a critical concern.Our study objective was to identify connectivity forest that through restoration support connectivity and biodiversity. The study area

Suppressing Halide Segregation Via Dual-Anchoring Strategy for 31.20% Perovskite/Silicon Tandem Solar Cells

The efficiency and stability of wide bandgap (WBG) perovskite solar cells (PSCs) are constrained by photo-induced halide segregation and severe non-radiative recombination, which significantly impedes the advancement of high-efficiency and stable perovskite/silicon tandem solar cells (PSTSCs). In this work, a potassium 4-sulfonic-1,8-naphthalic anhydride salt (4S-NAPS), featuring dual-anchoring si

Antineutrophil cytoplasmic antibody-associated vasculitis : insights into relapse risk and future management directions

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) has a relapsing-remitting course and, even with the availability of effective maintenance therapies such as rituximab, relapse rates remain high. Relapse is associated with the accrual of organ damage stemming from both the underlying disease and from the effects of AAV treatments; thus, early detection and proactive prevention

Mild or moderate hemophilia is not always a mild or moderate bleeding disorder : Back to the clinical phenotype

In a previous paper, a comprehensive clinicopathologic approach to mild and moderate bleeding disorders (MBD) was proposed by an international working group (IWG) as a part of a project promoted by the European Hematology Association (EHA) on the development of guidelines on the various MBDs. A single pre-diagnosis grade 4 bleeding event according to the ISTH-BAT scale or a comparable event after

Riddaren med svärdet : Ett unikt gravfynd på Lilla torg i Halmstad

Vid de arkeologiska utgrävningarna av franciskankonventet på Lilla torg i Halmstad påträffades många gravar, däribland en man som hade fått ett stort svärd med sig i graven. Han låg begravd bredvid en kvinna och en yngling . I artikeln undersöks vem denne man kan ha varit, hans släktband och sociala omständigheter samt varför han begravts just på denna plats. De tre gravlagda kopplas till den dans

STREAMS guidelines: standards for technical reporting in environmental and host-associated microbiome studies

The interdisciplinary nature of microbiome research, coupled with the generation of complex multi-omics data, makes knowledge sharing challenging. The Strengthening the Organization and Reporting of Microbiome Studies (STORMS) guidelines provide a checklist for the reporting of study information, experimental design and analytical methods within a scientific manuscript on human microbiome research

Cell-weighted polygenic risk scores are associated with β-amyloid and tau biomarkers in Alzheimer's disease

The molecular pathways influencing the build-up of β-amyloid and tau pathology in Alzheimer's disease are unclear. To investigate how the involvement of different cell types influences β-amyloid and tau, we utilized single-cell RNA-seq data to derive cell-weighted polygenic risk scores. We included participants from the BioFINDER-1 study, including cognitively unimpaired (N = 734) individuals and

The emergence of labour utopias : Solidarity, visibility and agency in the Swedish Municipal Workers’ Union strike

In 2003, the Swedish Municipal Workers’ Union (Kommunal) called a nationwide strike, demanding a pay rise for all members in the public sector. Drawing on oral history interviews with workplace representatives and local union officials, the article examines how the struggle enabled changes in subjectivity, generating utopian visions for increased visibility and agency for municipal workers. This p

Digital Public Diplomacy and the Illusion of the Online/Offline Divide

The rise of social media platforms in the early 2010’s marked a shift in public diplomacy practice resulting in the emergence of “digital public diplomacy.” This chapter explores the evolution of digital public diplomacy by emphasizing digital culture as a significant source of social and political change in a broader societization of diplomacy. Moving beyond a narrow focus on digitalization, it a

Reduced protein solubility - cause or consequence in amyloid disease?

In this perspective, we ask the question whether the apparently lower solubility of specific proteins in amyloid disease is a cause or consequence of the protein deposition seen in such diseases. We focus on Alzheimer's disease and start by reviewing the experimental evidence of disease-associated reduction in the measured concentration of amyloid β peptide, Aβ42, in cerebrospinal fluid. We propos

Improving taxonomic inference from ancient environmental metagenomes by masking microbial-like regions in reference genomes

Ancient environmental DNA is increasingly vital for reconstructing past ecosystems, particularly when paleontological and archaeological tissue remains are absent. Detecting ancient plant and animal DNA in environmental samples relies on using extensive eukaryotic reference genome databases for profiling metagenomics data. However, many eukaryotic genomes contain regions with high sequence similar

Toward an integrated research agenda for cryospheric change : a socio-glaciology approach

Non-technical summary. As glaciers shrink and disappear, the benefits they provide to people may also be fading. This makes it more important than ever to look closely at how melting glaciers affect both the environment and the communities that depend on them. To truly understand what is being lost- or even gained- we need to study glaciers from many angles. This includes looking at the science of

Improved droplet elongation model and value for surface tension of AuSi

Surface tension is crucial for nanowire vapor liquid solid (VLS) growth models and simulations of growth under external stimuli. A promising method involving imaging droplet deformation under an external electric field has previously been used to report the surface tension of the AuSi eutectic catalyst on Si-nanowires. However, simplified assumptions in this approach led to a significantly lower v