Objective. To explore whether infravesical outlet obstruction is associated with alterations in calcium activation of detrusor smooth muscle. Material and methods. Outlet obstruction was created by partial ligature of the urethra in female rats. Western blotting was performed using an antibody against the cytoplasmatic region of the alpha(1c) subunit of the L- type Ca2(+) channel. Intracellular ca

Apolipoprotein M (apoM) is a recently discovered human apolipoprotein predominantly present in high-density lipoprotein (HDL) in plasma, exclusively expressed in liver and in kidney. The function of apoM is yet unknown. The human apoM gene is located in the major histocompatibility complex class III region on chromosome 6. Because many genes located in this region are related to the immune respons

Sixty-two patients with lymphoedema of the arm after mastectomy and with hypertrophy of the adipose tissue were consecutively treated by liposuction in three different ways. The first group was operated on without the use of a tourniquet. In the second group, liposuction extended up to the distal edge of the tourniquet, and then into the proximal upper arm previously covered by the tourniquet usin

Reliable structural and statistical analyses of three dimensional protein structures should be based on unbiased data. The Protein Data Bank is highly redundant, containing several entries for identical or very similar sequences. A technique was developed for clustering the known structures based on their sequences and contents of alpha- and beta-structures. First, sequences were aligned pairwise.

The identification of a subterranean metallic ore from scattering experiments, conducted on the surface of the ground or in a bore hole, is a classic geophysical problem. In general this problem is not well-posed. However, a priori information about the shape of the target provides enough regularization to make the problem numerically stable. The problem is solved by minimizing the mean-square err

Popular Abstract in Swedish I rektorers uppdrag ingår ansvar för den pedagogiska verksamheten förändras och utvecklas. Den fråga som ställs i avhandlingen gäller om det finns en gemensam norm för hur rektorer tänker och handlar när det gäller den utvecklingsinriktade delen av ledaruppdraget. Om så är fallet hur ser den ut och kan den utvecklas? Bakgrund Stora förändringar på ett internationellt This thesis puts a focus on school leadership and school development. The local authorities took over responsibility for public education in 1991. At the same time, steerage by rules was abandoned in favour of steerage by goal-setting and result evaluation. The principal is an important link in this chain of steerage. The question posed by the thesis concerns whether there are common norms for th

Using a recently introduced multiplex polymerase chain reaction and restriction fragment length polymorphism ABO genotype screening method we have found an anomalous ABO genotype (A2O1variant) not correlating with the serological phenotype (blood group O). The blood group was confirmed by absorption/elution and detection of blood group substances in saliva. Sequencing of exons 6 and 7 in the ABO g

Three series of hard/soft styrene-acrylic latex based systems with equivalent compositions were prepared either by blending of homopolymer latexes or by preparing structured latex particles having core shell (CS) or inverted core shell (ICS) morphologies. Transmission electron microscopy (TEM) was used to investigate the particle morphologies, which were correlated to the calculated fractional rad

To describe demographics of tuberculosis ( TB) in the circle divide resund region, Southern Scandinavia, a retrospective analysis of epidemiological data from TB registers and population databases, from 1995 to 2002, was performed. A total of 2678 TB cases were reported with an overall incidence of 6.3 per 100,000 person-y of observation. There were major differences in notification rates among im

Objective: To monitor changes in serum concentrations of cartilage oligomeric matrix protein (COMP) during a 24-h period to determine any diurnal variation, and to estimate the half life of COMP in the circulation in patients with symptomatic knee osteoarthritis and in those with rheumatoid arthritis. Methods: Serum samples were drawn every 4 h (7 samples/patient over 24 h) in 10 patients with kne

Abstract in Undeterminedhe atJthor dlscusses the relalionship betwccn peaplc and animals in a lime perspective of millcllnia. The starting point is the pre-Chri stian. $can­ dinavl:m. animal graves ofJogs and hoJ'SCs. the Saami hear-graves, as wdl as animal burials urmodern time. TIle occurrence ofanimal graves In pre­ Christian time and the wide mnge ofways to dispose of human and animal bodics c

In this paper an excavation of a croft from the late 19th - early 20th century is presented. The artefact-material material i discussed and compared with information from contomporary written record. The artefact material and the writte documents yielded different kinds of information.

The paper studies the conditions optimum for the proliferation of neural cells at the surface of porous silicon. The results of this study show that the best results are achieved with meso-porous silicon. Geometrical properties of the wafers are also important through charge distribution at mask edges, change of hydrophobicity, degree of oxidation, the release of adhesion proteins from regeneratin

Magnesium chelatase is the first unique enzyme of the bacteriochlorophyll biosynthetic pathway. It consists of three subunits (BchI, BchD, and BchH). Amino acid sequence analysis of the Rhodobacter capsulatus BchH revealed a novel cysteine motif ((CX2CX3CX14C)-C-393) that was found in only six other proteobacteria (CX2CX3CX11-14C). The cysteine motif is likely to coordinate an unprecedented [Fe-S]