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Social functioning and the presentation of anxiety in children on the autism spectrum: A multimethod, multiinformant analysis
Co-occurring anxiety in children on the autism spectrum is associated with greater social challenges, including poorer social skills and relationships, which may influence the severity and presentation of anxiety symptoms, particularly social anxiety. The current study used Bayesian network analytics (Williams & Mulder, 2020) and a multimethod approach to examine (a) how different facets of so
Association of arterial stiffness with coronary artery calcium score in the general-population : the Swedish CArdioPulmonary bioImage study
OBJECTIVES: Coronary artery calcium score (CACS) is a marker of subclinical atherosclerosis. However, there is little data related to the association between arterial stiffness and CACS in the general population. The aim of this study was to explore the association between carotid femoral-pulse wave velocity (c-f PWV), a widely accepted marker of arterial stiffness, and CACS.METHODS: Participants
Systemic risk and network intervention
We consider a novel adversarial shock/protection problem for a class of network equilibria models emerging from a variety of different fields as continuous network games, production networks, opinion dynamic models. The problem is casted into a min-max problem and analytically solved for two particular cases of aggregate performances: the mean square of the equilibrium or of its arithmetic mean. T
Transformative Justice in Practice: Reflections on the Pastoral Land Commission During Brazil’s Political Transition
There has been a growing interest among transitional justice academics and practitioners in pursuing more transformative agendas for practice. There remain however few illustrations, if any, of work to deliver transformative justice in practice. This article considers the work of Brazil’s Pastoral Land Commission (CPT) during Brazil’s political transition as a potentially useful source of insights
Association of amyloid-β CSF/PET discordance and tau load 5 years later
OBJECTIVE: To investigate the association between discordant β-amyloid (Aβ) PET and CSF biomarkers at baseline and the emergence of tau pathology 5 years later. METHODS: We included 730 Alzheimer's Disease Neuroimaging Initiative (ADNI) participants without dementia (282 cognitively normal, 448 mild cognitive impairment) with baseline [18F]florbetapir PET and CSF Aβ42 available. Aβ CSF/PET status
The validity of astrological predictions on marriage and divorce : a longitudinal analysis of Swedish register data
This paper examines astrology, a concept that is considered unscientific by broad segments of the population in the western world. Despite this, astrology remains for some an important source for advice regarding choices in a range of different matters, including career and relationships. The continuing popularity of astrology may at least partly be linked to an insufficient body of empirical rese
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This paper proposes an advanced emergency control strategy for embedded VSC-HVDC links after AC disturbances, such as line tripping and generation loss. The control goals are to minimize the impact of the disturbance on the AC-network, which includes improving the long-term voltage stability with utilizing possible unloading capacity of parallel AC elements. The proposed algorithm is evaluated aga
In adults with obesity, copeptin is linked with BMI but is not associated with long-term exposure to cortisol and cortisone
Context: Obesity and cardiometabolic diseases are associated with higher long-term glucocorticoid levels, measured as scalp hair cortisol (HairF) and cortisone (HairE). Cardiometabolic diseases have also been associated with copeptin, a stable surrogate marker for the arginine-vasopressin (AVP) system. Since AVP is, together with corticotropin-releasing hormone (CRH) an important regulator of the
Transdiagnostic individualized clinically-based risk calculator for the automatic detection of individuals at-risk and the prediction of psychosis : external replication in 2,430,333 US patients
The real-world impact of psychosis prevention is reliant on effective strategies for identifying individuals at risk. A transdiagnostic, individualized, clinically-based risk calculator to improve this has been developed and externally validated twice in two different UK healthcare trusts with convincing results. The prognostic performance of this risk calculator outside the UK is unknown. All ind
The global scale, distribution and growth of aviation : Implications for climate change
Prior to the COVID-19 crisis, global air transport demand was expected to triple between 2020 and 2050. The pandemic, which reduced global air travel significantly, provides an opportunity to discuss the scale, distribution and growth of aviation until 2018, also with a view to consider the climate change implications of a return to volume growth. Industry statistics, data provided by supranationa
The Human Being as a Creator of (in) Human Life : The Example of Mary Shelley’s Frankenstein; or, the Modern Prometheus
Humans have an inquiring mind. Throughout history, one may find documentation that shows on human curiosity, and our drive to stretch boundaries to satisfy it. Thus, this is not something that characterizes our time in any particular way. Sources, for instance, from the 13th century can serve as good examples that support such an assumption. Mary Shelley’s novel from the 19th century, “Frankenstei
Costing analysis of a digital first-line treatment platform for patients with knee and hip osteoarthritis in Sweden
Osteoarthritis (OA) constitutes a major and increasing burden on patients, health care systems and the broader society. It is estimated that around a quarter of the adult population is affected by OA in the knee and hip and that the prevalence of OA will increase over the coming decades largely due to aging and adverse life-style factors. Prevention and effective care are critical to manage the ch
Plasma phosphorylated tau181 and neurodegeneration in Alzheimer’s disease
We examined if plasma phosphorylated tau is associated with neurodegeneration in Alzheimer’s disease. We investigated 372 cognitively unimpaired participants, 554 mild cognitive impairment patients, and 141 Alzheimer’s disease dementia patients. Tau phosphorylated at threonine 181, regional cortical thickness (using magnetic resonance imaging) and hypometabolism (using fluorodeoxyglucose positron
Proportionality and the human rights of companies under the ECHR - Whose interests are at stake?
This article considers whose interests may be at stake when a company claims its human rights under the European Convention on Human Rights (echr). In order to do that, the article will first investigate whether it makes sense to conceive of companies as persons capable of having their own interests. It finds that it is possible to do so. The article proceeds to analyse the case law of the Europea
Glucose effectiveness : Lessons from studies on insulin-independent glucose clearance in mice
Besides insulin-mediated transport of glucose into the cells, an important role is also played by the non-insulin-mediated transport. This latter process is called glucose effectiveness (acronym SG), which is estimated by modeling of glucose and insulin data after an intravenous glucose administration, and accounts for ≈70% of glucose disposal. This review summarizes studies on SG, mainly in human
Low temperature scanning tunneling microscopy and spectroscopy on laterally grown InxGa1-xAs nanowire devices
Laterally grown InxGa1-xAs nanowires (NWs) are promising candidates for radio frequency and quantum computing applications, which, however, can require atomic scale surface and interface control. This is challenging to obtain, not least due to ambient air exposure between fabrication steps, which induces surface oxidation. The geometric and electronic surface structures of InxGa1-xAs NWs and conta
Springtime drought shifts carbon partitioning of recent photosynthates in 10 year-old Picea mariana trees, causing restricted canopy development
How do Buddhists show their devotion to the Buddha?
Public preference for sustainable land use policies – Empirical results from multinomial logit model analysis
Public preferences for sustainable land use policy instruments and the motivations behind such preferences are important to make appropriate policies. Based on survey data (n = 309) from northeastern Somalia, we examined preferences for a set of land use policy instruments relative to no policy (i.e. the current status quo) and how cultural worldviews predict such preferences. We used a multinomia