Filtyp
Background: Despite newer treatments with immunosuppressive agents, there still exists a considerable morbidity and mortality risk among patients with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Since 1994 the European Vasculitis Society (EUVAS) has aimed for an improved outcome for patients with AAV, conducting several prospective randomized controlled trials (RCTs).
Diets rich in plant-based foods are encouraged for human health and to preserve resources and the environment but the nutritional quality and safety of such diets is debated. This study aimed to model nutritionally adequate diets with increasing plant food content and to characterise the derived diets using a multicriteria approach including, nutrients intake, environmental pressures and exposure
A search for new phenomena has been performed in final states with at least one isolated high-momentum photon, jets and missing transverse momentum in proton–proton collisions at a centre-of-mass energy of s = 13 TeV. The data, collected by the ATLAS experiment at the CERN LHC, correspond to an integrated luminosity of 139 fb−1. The experimental results are interpreted in a supersymmetric model in
Context. The motion of stars has been used to reveal details of the complex history of the Milky Way, in constant interaction with its environment. Nevertheless, to reconstruct the Galactic history puzzle in its entirety, the chemo-physical characterisation of stars is essential. Previous Gaia data releases were supported by a smaller, heterogeneous, and spatially biased mixture of chemical data f
This paper presents a search for a new Z′ vector gauge boson with the ATLAS experiment at the Large Hadron Collider using pp collision data collected at s = 13 TeV, corresponding to an integrated luminosity of 139 fb −1. The new gauge boson Z′ is predicted by Lμ − Lτ models to address observed phenomena that can not be explained by the Standard Model. The search examines the four-muon (4μ) final s
Exposure to natural environments is thought to benefit mental and physical health. A better understanding of the interplay between the individual and the environment in relation to public health is imperative in light of the joint biodiversity, climate, and health crises. This study aimed to 1) identify Body Mass Index (BMI) trajectories in the Scania Public Health Cohort (SPHC), 2) characterise t
BackgroundDuring pregnancy and delivery, hemodynamics are altered and complex congenital heart disease has been associated with adverse maternal and neonatal outcomes. We sought to investigate pregnancy outcome and complications in relation to complexity of heart condition.Materials and methodsWe studied women with ACHD discussed at multidisciplinary conferences at Lund University Hospital March 2
It is well known that the intensive biogeochemical activity in hyporheic zone of groundwater and antibiotic contaminated river water induced the pollution diffusion and variation of biogeochemical transformation. However, the complex interaction process caused by water level fluctuation is difficult to accurately depict on a larger, catchment scale. Therefore, a loosely coupled HYDRUS-3D/GMS was e
Process-based land surface models are important tools for estimating global wetland methane (CH4) emissions and projecting their behavior across space and time. So far there are no performance assessments of model responses to drivers at multiple time scales. In this study, we apply wavelet analysis to identify the dominant time scales contributing to model uncertainty in the frequency domain. We
Terrestrial ecosystems are the largest sink for carbon, and their ecosystem gross primary productivity (GPP) regulates variations in atmospheric carbon dioxide (CO2) concentrations. Current process-based ecosystem models used for estimating GPP are subject to large uncertainties due to poorly constrained parameter values. In this study, we implemented a global sensitivity analysis (GSA) on paramet
OBJECTIVE: The Acromegaly Consensus Group reconvened in November 2007 to update guidelines for acromegaly management.PARTICIPANTS: The meeting participants comprised 68 pituitary specialists, including neurosurgeons and endocrinologists with extensive experience treating patients with acromegaly. EVIDENCE/CONSENSUS PROCESS: Goals of treatment and the appropriate imaging and biochemical and clinica
BACKGROUND: GH therapy in adult patients with GH deficiency (GHD) was approved over 10 yr ago, and the indication has subsequently gained broad acceptance. The HypoCCS surveillance database is a suitable means to examine the evolution of diagnostic patterns since 1996.METHODS: Baseline demographics, reported cause of GHD, and diagnostic tests were available from 5893 GH-treated patients. Trends fo
Artificial intelligence (AI) is emerging as an impactful feature of the life, planning and governance of 21st-century cities. Once confined to the realm of science fiction and small-scale technological experiments, AI is now all around us, in the shape of urban artificial intelligences including autonomous cars, robots, city brains and urban software agents. The aim of this article is to criticall
In this study of the effects of lead on the endocrine system, 77 secondary lead-smelter workers (i.e., 62 active and 15 retired) were compared with 26 referents. Lead concentrations were determined in plasma with inductively coupled plasma mass spectrometry (i.e., index of recent exposure), in blood with atomic absorption spectrophotometry, and in fingerbone with K x-ray fluorescence technique (i.
This article presents models to predict the time until mechanical failure of in-ground wooden test specimens resulting from fungal decay. Historical records of decay ratings were modelled by remotely sensed data from ERA5-Land. In total, 2,570 test specimens of 16 different wood species were exposed at 21 different test sites, representing three continents and climatic conditions from sub-polar to
BackgroundAchromobacter xylosoxidans is an emerging pathogen that causes airway infections in patients with cystic fibrosis. Knowledge of virulence factors and protein secretion systems in this bacterium is limited. Twin arginine translocation (Tat) is a protein secretion system that transports folded proteins across the inner cell membranes of gram-negative bacteria. Tat has been shown to be impo
