We evaluate the shared genetic regulation of mRNA molecules, proteins and metabolites derived from whole blood from 3029 human donors. We find abundant allelic heterogeneity, where multiple variants regulate a particular molecular phenotype, and pleiotropy, where a single variant associates with multiple molecular phenotypes over multiple genomic regions. The highest proportion of share genetic re

Using element-specific measurements of the ultrafast demagnetization of Ru/Fe65Co35 hetero-structures, we show that Ru can exhibit a significant magnetic contrast (3% asymmetry) resulting from ultrafast spin currents emanating from the demagnetization process of the FeCo layer. We use this magnetic contrast to investigate how superdiffusive spin currents are affected by the doping of heavy element

The ability to measure flying insect activity and abundance is important for ecologists, conservationists and agronomists alike. However, existing methods are laborious and produce data with low temporal resolution (e.g. trapping and direct observation), or are expensive, technically complex, and require vehicle access to field sites (e.g. radar and lidar entomology). We propose a method called “C

We theoretically investigate a supersolid structure taking the form of stacked, disk-shaped superfluid droplets connected via a dilute superfluid, in an antidipolar condensate. A phase diagram is determined for varying the particle number and scattering length, identifying the regions of a regular dipolar superfluid, supersolid stacks, and isolated stacked disk-shaped droplets in an experimentally

The transition to agile manufacturing, Industry 4.0, and high-mix-low-volume tasks require robot programming solutions that are flexible. However, most deployed robot solutions are still statically programmed and use stiff position control, which limit their usefulness. In this paper, we show how a single robot skill that utilizes knowledge representation, task planning, and automatic selection of

A search for forward proton scattering in association with light-by-light scattering mediated by an axion-like particle is presented, using the ATLAS Forward Proton spectrometer to detect scattered protons and the central ATLAS detector to detect pairs of outgoing photons. Proton-proton collision data recorded in 2017 at a centre-of-mass energy of s = 13 TeV were analysed, corresponding to an inte

As #MeToo activists took their testimonies of sexual harm outside the legal arena to seek justice, the #MeToo movement has commonly been framed as pitting informal justice-seeking against formal law. This article draws on interviews with Swedish #MeToo activists and focuses on their experiences of justice seeking. It asks the key question: what does justice look like for #MeToo participants? I dem

Background: Lumbar puncture (LP) is a common invasive procedure, most frequently performed to diagnose infection. Physicians perform LP in newborn infants with the help of an assistant using a strict aseptic technique; it is important to monitor the infant during all the steps of the procedure. Without adequate analgesia, LP can cause considerable pain and discomfort. As newborns have increased se

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High cBN content PCBN material with 2-15 wt. % TiB2 binder matrix.This disclosure relates to a high cBN content polycrystalline cubic boron nitride, PCBN, material. The binder matrix material comprises 2 to 15 wt.% titanium diboride (TiB2).

This book provides an overview of the history of knowledge, including its main currents, distinguishing ideas, and key concepts. However, it is not primarily a state-of-the-art overview but rather an argumentative contribution that seeks to push the field in a certain direction – towards studying knowledge in society and knowledge in people's lives. Hence, the history of knowledge envisioned by th

Som en del av HORIZON EUROPE-projektet AfroSAFE: Säkert system för radikal förbättring av trafiksäkerheten i afrikanska låg- och medelinkomstländer, en översyn av nationella bestämmelser, riktlinjer och procedurer för väginfrastruktursäkerhetshantering (RISM), såväl som vägar. designriktlinjer utfördes i Ghana, Tanzania och Zambia. Information samlades in från relevanta myndigheter och granskningeAs part of the HORIZON EUROPE project AfroSAFE, a review of national regulations, guidelines, and procedures for Road Infrastructure Safety Management (RISM), as well as road design guidelines was carried out in Ghana, Tanzania, and Zambia. Information was collected from relevant authorities and the review had special attention to the safety of vulnerable road users (pedestrians, cyclists, and mot

The effects of NPM have been criticized for decades and we are now seeing how alternative, post-NPM, governance innovations emerge. What joins these innovations is the critique against NPM and the ambition to provide new ways of governing public organizations. From a critical stance, we engage in a discussion of governance innovations from the perspective of social imaginaries and analyse post-NPM

This thesis explores how Salesian Institutes are related to religious peace-building in post-colonial and post-conflict Cambodia. It examines if and how the Catholic-Salesian multi-religious educational mission system is able to peacefully co-exist in a Buddhist Cambodian society, and collaborate with other minority religions present – Protestant, Muslim, and non-religious in promoting education f

Med utgångspunkt i ett fabelmotiv i Lunds domkyrkas korstolar - räven och storken som bjuder varandra på middag - tecknas fabelgenrens historia från medeltid till idag.

Introduction Modern systemic treatment has reduced incidence of regional recurrences and improved survival in breast cancer (BC). It is thus questionable whether regional radiotherapy (RT) is still beneficial in patients with sentinel lymph node (SLN) macrometastasis. Postoperative regional RT is associated with an increased risk of arm morbidity, pneumonitis, cardiac disease and secondary cancer.

This article draws on usability evaluations of a behavioural change intervention delivered as a web-based course. Special attention was given to usability as the course is directed at older adults aged 70 and above. Experiences from the usability evaluations in a lab environment and the real world, followed by stepwise refinements, can serve as examples of what must be considered in developing cou