Sökresultat
Filtrera
Filtyp
Din sökning på "*" gav 529364 sökträffar
Disentangling the Early History of the Solar System
Giant planets form out of a disc of gas and dust – called protoplanetary disc -- that surrounded the protosun at the time of its formation. While the cores of giant planets were growing via planetesimal and pebble accretion, they started to interact with the gas in the protoplanetary disc. These interactions can lead to inward migration of all the four giant planets in our Solar System during the
Do credit ratings measure financial constraints?
Neural processing of changes in phonetic and emotional speech sounds and tones in preterm infants at term age
Objective: Auditory change-detection responses provide information on sound discrimination and memory skills in infants. We examined both the automatic change-detection process and the processing of emotional information content in speech in preterm infants in comparison to full-term infants at term age. Methods: Preterm (n = 21) and full-term infants' (n = 20) event-related potentials (ERP) were
Using Patchy Particles to Prevent Local Rearrangements in Models of Non-equilibrium Colloidal Gels
Simple models based on isotropic interparticle attractions often fail to capture experimentally observed structures of colloidal gels formed through spinodal decomposition and subsequent arrest: the resulting gels are typically denser and less branched than their experimental counterparts. Here, we simulate gels formed from soft particles with directional attractions ("patchy particles"), designed
Availability, prices and affordability of essential medicines for treatment of diabetes and hypertension in private pharmacies in Zambia
Objectives: To explore availability, prices and affordability of essential medicines for diabetes and hypertension treatment in private pharmacies in three provinces of Zambia. Methods: A cross-sectional survey was conducted in 99 pharmacies across three Zambian provinces. Methods were based on a standardized methodology by the World Health Organization and Health Action International. Availabilit
Co-afflicted but invisible : A qualitative study of perceptions among informal caregivers in cancer care
This article explores the lived experience of informal caregivers in cancer care, focusing on the perceived burden and needs of individuals seeking support from an informal group for next of kin. A total of 28 individuals who were closely related to a patient with cancer participated in focus group interviews. Three themes were identified: setting aside one’s own needs, assuming the role of projec
Inhibition of histone demethylases LSD1 and UTX regulates ERα signaling in breast cancer
In breast cancer, Lysine-specific demethylase-1 (LSD1) and other lysine demethylases (KDMs), such as Lysine-specific demethylase 6A also known as Ubiquitously transcribed tetratricopeptide repeat, X chromosome (UTX), are co-expressed and co-localize with estrogen receptors (ERs), suggesting the potential use of hybrid (epi)molecules to target histone methylation and therefore regulate/redirect hor
Nynäs : en vägledning genom herrgårdsbyggnaden
Risk factors associated with prolonged intestinal colonization of ESBL-producing Enterobacteriaceae – a prospective cohort study
Renal arteriovenous shunting in rejecting allograft, hydronephrosis, or haemorrhagic hypotension in the rat
We studied the occurrence of arteriovenous (A-V) shunting in three experimental rat models, namely in rejecting allograft kidney, in uni- or bilateral ureteral obstruction, and in haemorrhagic hypotension. Isografted or sham-operated rats served as controls. Radiolabelled microspheres were injected into the renal artery and the increase in the amount of radioactivity in the lungs was considered to
Social Networks and Reputation Incentives: Implications for Directors' Effort and Firm Valuation in Sweden.
Assessing lesion malignancy by scanning small-angle x-ray scattering of breast tissue with microcalcifications
Scanning small-angle x-ray scattering (SAXS) measurements were performed on 36 formalin-fixed reast tissue biopsies obtained from two patients. All samples contained microcalcifications of ype II, i.e. ormed by hydroxyapatite. We demonstrate the feasibility of classifying breast lesions by canning SAXS of issues containing microcalcifications with a resolution of 35 μm x30 μm. We eport a character
Exploring tags through videography
This article focuses on videography as a method for conducting research, as a means of communicating findings about tags and tagging to the public, and an opportunity to re-evaluate previously-collected empirical material.Based on ongoing explorative videographic research, the author discusses how the video medium can be used to go beyond the mere visual representation of tags as singular expressi
Pharmacology and signaling properties of epidermal growth factor receptor isoforms studied by bioluminescence resonance energy transfer
We have developed a new assay for measuring epidermal growth factor receptor (EGFR) activation using the bioluminescence resonance energy transfer (BRET) technology, which directly measures the recruitment of signaling proteins to activated EGFR. Our results demonstrate that EGFR BRET assays precisely measure the pharmacology and signaling properties of EGFR expressed in human embryonic kidney 293
Solution-phase parallel Wittig olefination : Synthesis of substituted 1,2-diarylethanes
An efficient strategy for solution-phase parallel synthesis of substituted 1,2-diarylethanes is described. A stilbene library was initially generated by Wittig olefination utilizing amino-labeled phosphines. The stilbene analogues were obtained in high yields and excellent purities after solid-phase extraction. Subsequent reduction of the stilbene libraries simultaneously unmasked functional group
Benzodiazepines influence melatonin secretion of the pineal organ of the trout in vitro
Gustaf Adolf Reuterholms liv och person
Biografisk introduktion
Differential impedance spectra analysis reveals optimal actuation frequency in bulk mode acoustophoresis
This work reports a method to select the optimal working frequency in transversal bulk resonator acoustophoretic devices by electrical impedance measurements. The impedance spectra of acoustophoretic devices are rich in spurious resonance peaks originating from different resonance modes in the system not directly related to the channel resonance, why direct measurement of the piezoelectric transdu
Deep sequencing of myxoinflammatory fibroblastic sarcoma
Myxoinflammatory fibroblastic sarcoma (MIFS) has recurrent genetic features in the form of a translocation t(1;10)(p22-31;q24-25), BRAF gene fusions, and/or an amplicon in 3p11-12 including the VGLL3 gene. The breakpoints on chromosomes 1 and 10 in the t(1;10) cluster in or near the TGFBR3 and OGA genes, respectively. We here used a combination of deep sequencing of the genome (WGS), captured sequ