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Objective: To systematically evaluate which lesion-based imaging features and methods allow for the best statistical prediction of poststroke deficits across independent datasets. Methods: We utilized imaging and clinical data from three independent datasets of patients experiencing acute stroke (N1 = 109, N2 = 638, N3 = 794) to statistically predict acute stroke severity (NIHSS) based on lesion v
Based on ethnographic fieldwork, this article is concerned with how undocumented refugees and migrants use invisibility strategies to navigate a hostile host environment in Western Tanzania. This article explores how the shifts in Tanzania’s refugee policy have affected different generations of refugees differently, and how older cohorts assist newer cohorts. This article argues that the challenge
Background: Even though children after tonsil surgery experience pain and other limitations in their daily lives, nursing care is transferred to parents after tonsil surgery, and they might need some kind of support. The aim of the study was to test the design of a randomized controlled trial intended to evaluate a nurse-led telephone follow-up after tonsil surgery on postoperative symptoms and qu
Activating FLT3 and RAS mutations commonly occur in leukemia with KMT2A-gene rearrangements (KMT2A-r). However, how these mutations cooperate with the KMT2A-r to remodel the epigenetic landscape is unknown. Using a retroviral acute myeloid leukemia (AML) mouse model driven by KMT2A::MLLT3, we show that FLT3ITD, FLT3N676K, and NRASG12D remodeled the chromatin accessibility landscape and associated
Knowledge management is pivotal in innovation using mechanisms to facilitate knowledge exchange and learning among competitive tourism organisations and destinations. Nevertheless, both the tourism industry and its scholars have been slow to embrace the field leaving it relatively underdeveloped. Knowledge management, as a sequential process of capturing, developing, sharing, and leveraging from o
Identifying biomarkers in fibrotic lung disease is key for early anti-fibrotic intervention. Dynamic contrast-enhanced (DCE) MRI offers valuable perfusion-related insights in fibrosis but adapting human MRI methods to rodents poses challenges. Here, we explored these translational challenges for the inflammatory and fibrotic phase of a bleomycin lung injury model in rats. Eleven male Sprague-Dawle
A series of orthoborate-based ionic materials of bis(glycolato)borate ([BGB]) and bis(ethylene-1,2-dioxy)borate anions ([BEDB]) coupled with tetrabutylphosphonium ([P4444]) and tetrabutylammonium ([N4444]) cations have been synthesized, and their physicochemical properties are characterized. The ionic materials based on the most popular orthoborate anion, bis(oxalato)borate anion ([BOB]), which co
Human monocarboxylate transporters (hMCTs) belong to the solute carrier 16 (SLC16) family of proteins and are responsible for the bi-directional transport of various metabolites, including monocarboxylates, hormones, and aromatic amino acids. Hence, the metabolic role of hMCTs is undisputable, as they are directly involved in providing nutrients for oxidation and gluconeogenesis as well as partici
Introduction: Preterm delivery (PTD) is the leading cause of death in children under 5 years of age. Cervical shortening detected by ultrasound can be used to predict PTD, but prediction is not perfect, and complementary diagnostic markers are needed. Recently, specific plasma microribonucleic acid (miRNAs) detected in early second trimester were shown to be associated with spontaneous PTD in high
Biodiversity records are of great importance, especially in light of the biodiversity crisis. Here, we present a study on the diversity of rotifers in Bolivia based on an extensive investigation of the literature published so far. Through this approach and an analysis of samples from 207 water bodies of the country, we updated the checklist of reported species. This study revealed a total of 195 s
Situation awareness in driving involves detection of events and environmental changes. Failure in detection can be attributed to the density of these events in time, amongst other factors. In this research, we explore the effect of temporal proximity, and event duration in a change detection task during driving in VR. We replicate real-world interaction events in the streetscape and systematically
Tourism is consistently affected by a change. Whether it be economic, social, and cultural, or whether it be technological and environmental, which are the focus of much contemporary tourism scholarship. Furthermore, change occurs at different scales and is uneven over space and time. Therefore, while all change is experienced locally, global overviews such as that provided in this book can only p
Context. Star clusters, composed of stars born from the same molecular cloud, serve as invaluable natural laboratories for understanding the fundamental processes governing stellar formation and evolution. Aims. This study aims to investigate correlations between the Mean Interdistance (Di), Mean Closest Interdistance (Dc) and Median Weighted Central Interdistance (Dcc) with the age of star cluste
To steer the economy towards a low-carbon future and mitigate climate change, the European Union Emissions Trading System (EU ETS) has been established at the European level. It operates through a cap-and-trade mechanism and currently regulates around 40% of the EU’s CO2 emissions. However, due to regional differences in the industry mix and the spatial concentration of regulated industrial instal
How do the limits of high-level visual processing affect human performance in naturalistic, dynamic settings of (multimodal) interaction where observers can draw on experience to strategically adapt attention to familiar forms of complexity? In this backdrop, we investigate change detection in a driving context to study attentional allocation aimed at overcoming environmental complexity and tempor
