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Geometrical restoration during total hip arthroplasty is related to change in gait pattern - a study based on computed tomography and three-dimensional gait analysis

Background: The effect of change in hip anatomy on change in gait pattern is not well described in current literature. Therefore, our primary aim was to describe and quantify changes in hip geometry and gait pattern 1 year after total hip arthroplasty (THA) in individuals with hip osteoarthritis. Our secondary aim was to explore the effect of postoperative change in femoral neck anteversion (FNA)

Polarization effects in Raman spectroscopy of light-absorbing carbon

Raman spectroscopy is widely used for characterization of carbon-based mate- rials including light-absorbing carbonaceous (LAC) matter. However, informa- tion on polarization properties of these materials are generally lacking, and often the polarization characteristics of experiments are not presented in the literature thereby giving uncertainty to presented data. In this work, the polari- zation

Potential immunoregulatory role of T and dendritic cells in cancer : Investigations based on transcriptional analysis

Cancer is a complex disease with various genetic and epigenetic driving factors. Cancer cells form a favored microenvironment to sustain their uncontrolled behavior leading to abnormal growth. With standard treatment including chemotherapy, relapse risk is high due to the resistance that cancer cells can develop against chemotherapy agents. Immuno-oncological therapeutics, as alternatives, have sh

Policies in Hard Times: Assessing the Impact of Financial Crises on Structural Reforms

It is commonly argued that crises open up a window of opportunity to implement policies that otherwise would not have the necessary political backing. The argument goes that the political cost of economic and social reforms declines as crises unravel structural problems that need to be urgently rectified and the public is more willing to bear the pains associated with such reforms. This paper cast

Working with startups? these are the three things you ought to know about startup teams

While much has been written about how startups work to develop their product, this paper focuses instead on how to manage the startup team. Based on a systematic review of current research, I present actionable insights about startup team characteristics; who they are, how they work, and how they stay together. I explain how these characteristics imply both opportunities and threats for the viabil

Oppositional voting in the Council of the EU between 2010 and 2019: Evidence for differentiated politicisation

This article presents a new and previously unchartered dataset on roll call votes for all 28 member states in the Council of the EU between 2010 and 2019 and studies the effects of politicisation on governments' oppositional voting in the different policy areas. We contribute to the literature with two main findings. First, our study provides strong evidence for bottom-up politicisation, where Eur

Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease

Highly pathogenic emm1 Streptococcus pyogenes strains secrete the multidomain Streptococcal inhibitor of complement (SIC) that binds and inactivates components of the innate immune response. We aimed to determine if naturally occurring or vaccine-induced antibodies to SIC are protective against invasive S. pyogenes infection. Immunisation with full-length SIC protected mice against systemic bacter

Strategies to reduce sample sizes in Alzheimer’s disease primary and secondary prevention trials using longitudinal amyloid PET imaging

Background: Detecting subtle-to-moderate biomarker changes such as those in amyloid PET imaging becomes increasingly relevant in the context of primary and secondary prevention of Alzheimer’s disease (AD). This work aimed to determine if and when distribution volume ratio (DVR; derived from dynamic imaging) and regional quantitative values could improve statistical power in AD prevention trials. M

Optimisation of large-radius jet reconstruction for the ATLAS detector in 13 TeV proton–proton collisions

Jet substructure has provided new opportunities for searches and measurements at the LHC, and has seen continuous development since the optimization of the large-radius jet definition used by ATLAS was performed during Run 1. A range of new inputs to jet reconstruction, pile-up mitigation techniques and jet grooming algorithms motivate an optimisation of large-radius jet reconstruction for ATLAS.

Making a (Political) Career: Young Party Members and Career‐Related Incentives for Party Membership

Few empirical studies have investigated career‐related incentives for party membership, including for young party members. Through the lens of rational choice, we ask what career‐related incentives young and active party members consider when calculating costs and benefits of party membership. We argue for a broad understanding of career‐related incentives, including careers outside party politics

Secondary aerosol formation from dimethyl sulfide-improved mechanistic understanding based on smog chamber experiments and modelling

Dimethyl sulfide (DMS) is the dominant biogenic sulfur compound in the ambient marine atmosphere. Low-volatility acids from DMS oxidation promote the formation and growth of sulfur aerosols and ultimately alter cloud properties and Earth's climate. We studied the OH-initiated oxidation of DMS in the Aarhus University Research on Aerosol (AURA) smog chamber and the marine boundary layer (MBL) with

III-V Nanowire MOSFET High-Frequency Technology Platform

This thesis addresses the main challenges in using III-V nanowireMOSFETs for high-frequency applications by building a III-Vvertical nanowire MOSFET technology library. The initial devicelayout is designed, based on the assessment of the current III-V verticalnanowire MOSFET with state-of-the-art performance. The layout providesan option to scale device dimensions for the purpose of designing vari

Femoral strength and strains in sideways fall : Validation of finite element models against bilateral strain measurements

Low impact falls to the side are the main cause of hip fractures in elderly. Finite element (FE) models of the proximal femur may help in the assessment of patients at high risk for a hip fracture. However, extensive validation is essential before these models can be used in a clinical setting. This study aims to use strain measurements from bilateral digital image correlation to validate an FE mo

Machinability of Single-phase Materials : Surface integrity and tool wear analysis

The quality and performance of products are particularly important in sectors such as research facilities and in the nuclear, military and space industries. These sectors make use of high-performance materials that are uncommon in other contexts and therefore place high requirements on personnel, machines and tools. While tool manufacturers have readily available tool selection guides and cutting