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Introduction of a method to calculate cumulative age- And gender-specific lifetime attributable risk (LAR) of cancer in populations after a large-scale nuclear power plant accident

The effect of age and gender in risk estimates related to long-term residence in areas contaminated by nuclear power plant fallout was evaluated by applying the lifetime attributable risk (LAR) concept to an existing exposure model that was previously used for cumulative effective dose estimates. In this study, we investigated the influence of age distribution on the number of cancer cases by appl

Innovation and Employment: Process versus Product Innovation

Which kinds of growth lead to increased employment and which do not? This is one of the questions that this important volume attempts to answer. The book explores the complex relationships between innovation, growth and employment that are vital for both research into, and policy for, the creation of jobs.Politicians claiming that more rapid growth would remedy unemployment do not usually specify

Policy Implications

Our investigation and analysis of public technology procurement has demonstrated that, as argued in Chapter 1 of this book, it is a concept with salient features. These distinguish it from other types of public procurement. With this particular type of procurement, policy makers are faced with new challenges. The reasons pursuing for public technology procurement, and consequently its processes an

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Effect of sustained mental work on the first stage of mental rotation was studied by the method of intracortical interaction. It was revealed that during sustained mental work the zone of the high level of connections in the alpha-band was considerably reduced due to an increase of specificity, rationality of thinking. In the beta-band the zone of the high connection level moved from the central a

A phase III study of INCB054828 as adjuvant therapy in patients (pts) with high-risk urothelial carcinoma (UC) harboring fibroblast growth factor receptor 3 (FGFR3) genomic alterations

Background: After neoadjuvant chemotherapy (NAC), about 20% of pts with muscle-invasive UC are found to have advanced pT-stage or lymph node involvement and 5-year overall survival (OS) of them is < 30%. Tumor samples from these pts may provide information about chemotherapy resistance, and may predict for the activity of new drugs given postoperatively. Alterations of FGFR3 gene represent a thera

Traveling waves and trial averaging : The nature of single-trial and averaged brain responses in large-scale cortical signals

Analyzing single trial brain activity remains a challenging problem in the neurosciences. We gain purchase on this problem by focusing on globally synchronous fields in within-trial evoked brain activity, rather than on localized peaks in the trial-averaged evoked response (ER). We analyzed data from three measurement modalities, each with different spatial resolutions: magnetoencephalogram (MEG),

Dissociation of early evoked cortical activity in perceptual grouping

Perceptual grouping is a multi-stage process, irreducible to a single mechanism localized anatomically or chronometrically. To understand how various grouping mechanisms interact, we combined a phenomenological report paradigm with high-density event-related potential (ERP) measurements, using a 256-channel electrode array. We varied the relative salience of competing perceptual organizations in m

Dynamics of spontaneous transitions between global brain states

Phase patterns of human scalp alpha EEG activity show spontaneous transitions between different globally phase-synchronized states. We studied the dynamical properties of these transitions using the method of symbolic dynamics. We found greater predictability (deterministicity) and heterogeneity in the dynamics than what was expected from corresponding surrogate series in which linear correlations

Adsorption of Fibrinogen on Silica Surfaces-The Effect of Attached Nanoparticles

When a biomaterial is inserted into the body, proteins rapidly adsorb onto its surface, creating a conditioning protein film that functions as a link between the implant and adhering cells. Depending on the nano-roughness of the surface, proteins will adsorb in different amounts, with different conformations and orientations, possibly affecting the subsequent attachment of cells to the surface. Th