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Pathogenesis of chronic pancreatitis: A comprehensive update and a look into the future.

Chronic pancreatitis is a relatively frequent condition usually caused by alcoholic abuse but also due to recurrent gallstone disease, metabolic endocrine disorders and haemochromatosis, among others. Specific types such as hereditary and autoimmune pancreatitis should be particularly kept in mind and emphasized, as they require specific treatment and attention. The possibility to identify gene mu

The complexity in the implementation process of empowerment-based chronic kidney care: a case study.

This study is part of an interactive improvement intervention aimed to facilitate empowerment-based chronic kidney care using data from persons with CKD and their family members. There are many challenges to implementing empowerment-based care, and it is therefore necessary to study the implementation process. The aim of this study was to generate knowledge regarding the implementation process of

ImmTree: database of evolutionary relationships of genes and proteins in the human immune system.

The immune system, which is a complex machinery, is based on the highly coordinated expression of a wide array of genes and proteins. The evolutionary history of the human immune system is not well characterised. Although several studies related to the development and evolution of immunological processes have been published, a full-scale genome-based analysis is still missing. A database focused o

Statistical Modelling of Cell Cycle Dynamics Analysis and Interpretation of BrdUrd DNA FCM-Derived Data

Popular Abstract in Swedish Cancer är en av de vanligaste dödsorsakerna i Sverige idag och att kunna ge cancerpatienter en bättre behandling är därför av stort intresse. En del av detta arbete består av att förbättra förståelsen för hur en cellpopulation, eller då speciellt en cancertumör, växer. Ett medel för att öka kunskapen på området är att använda matematiska modeller. Förmågan att kunna föIt it of great importance to increase the knowledge of various cell cycle kinetic parameters and the objective of this thesis is to use stochastic models to interpret Bromodeoxyuridine (BrdUrd) DNA Flow Cytometry (FCM) derived data in order to estimate such parameters. The cell cycle is the process of growth and division that is essential for an organism to increase in size. The cell cycle consist

The 6-item CTS symptoms scale: a brief outcomes measure for carpal tunnel syndrome.

OBJECTIVE: To develop a psychometrically appropriate brief symptoms measure of carpal tunnel syndrome (CTS). METHODS: Preoperative CTS 11-item symptom severity and 8-item functional status scales from 693 patients (71% women) with CTS were subjected to exploratory factor analysis and item response theory (IRT) analysis yielding a revised CTS symptoms scale. A validation sample of 213 patients (68%

Prefracture functional level evaluated by the New Mobility Score predicts in-hospital outcome after hip fracture surgery.

BACKGROUND AND PURPOSE: Clinicians need valid and easily applicable predictors of outcome in patients with hip fracture. Adjusting for previously established predictors, we determined the predictive value of the New Mobility score (NMS) for in-hospital outcome in patients with hip fracture. PATIENTS AND METHODS: We studied 280 patients with a median age of 81 (interquartile range 72-86) years who

Attitudes towards people with mental illness: a cross-sectional study among nursing staff in psychiatric and somatic care.

Stigma and discrimination have been identified as important obstacles to the integration of people with mental illness in society. In efforts to reduce stigma and discrimination, health professionals play an important role as they have frequent contact with and responsibility for treatment and rehabilitation of consumers. The aim of the present study was to investigate attitudes towards mental ill

Does informal support influence social participation of fractured elderly people?

This population-based cross-sectional study describes social participation expressed as the accomplishment of social, cultural, and leisure activities resulting from informal support given by relatives or friends, formal support given by the municipality or county, or a combination of the two, among 452 individuals aged 60-93 years suffering from osteoporosis-related fractures. A fourth group of i

Radiography of the mandible prior to endosseous implant treatment. Localization of the mandibular canal and assessment of trabecular bone.

Mandibular autopsy specimens were examined with different radiographic techniques in order to evaluate the visibility of the mandibular canal and the measurement accuracy of distances related to the mandibular canal. Hypocycloidal, spiral and computed tomography (CT) were superior to periapical and panoramic radiography in visualising the mandibular canal. The tomographic techniques were more accu

Incidence and management of complications after branched and fenestrated endografting.

Endovascular treatment of complex aortic aneurysms with fenestrated and branched stentgrafts is in rapid development. Early and midterm results from centers of excellence are very promising but the technique is still in its infancy. With the introduction of EVAR for complex aneurysms a new set of failure modes have also been introduced. These relate both to the specific deployment techniques of th

Essays on Financial Market Volatility

This thesis examines the volatility in the equity and short-term interest-rate markets, and the spillover from the short term interest rate market to the equity market. It consists of three papers and focuses on adapting and proposing models for the estimation and forecasting of financial market volatility. Chapter 1 gives a brief introduction to the parametric and nonparametric volatility models,

Verbs with an Attitude

The aim of this paper is to investigate some semantic and syntactical properties of verbs of propositional attitude, using data from English, German, Swedish, Italian and Gallipolino (a dialect from South Italy). The work is based on the distinction between situational and actional attitude as proposed by Ray Jackendoff (Jackendoff, Language, Consciousness and Culture, MIT Press, Cambridge, 2007).