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There has been great interest in the rationales for transformative innovation policies (TIP), including those following a mission-oriented logic. However, few studies have investigated how public administration can effectively implement TIP. To study this, we first identify from existing literature four TIP governance tasks (creating legitimacy and leadership, coordination across levels/instrument

Predicting probiotic strain properties that translate into beneficial effects in the host is challenging and could be considered the holy grail in developing new probiotics. One approach is to selectively evolve well-studied probiotic strains known to elicit beneficial effects in clinical studies. In this study, Limosilactobacillus reuteri DSM 17938, among the world's most studied probiotic strain

Purpose: This investigation was designed to examine the effects of self-monitored training combined with the use of delayed auditory feedback (DAF), on the accuracy of articulation in acquired apraxia of speech (AOS). Background: The increased number of stroke survivors leads to higher societal costs when it comes to e.g., rehabilitation. Speech and language deficits post stroke can be diminished

The current paper focuses on the conceptual design and numerical analysis of a four-stage centrifugal pump for the fuel system of a turbofan engine with liquid hydrogen as fuel. Liquid hydrogen is challenging at high pressures due to its special fluid properties. The design condition for the pump is set at take-off, to raise the pressure of liquid hydrogen from 6 bars at the outlet of a low-pressu

Context. Hot Jupiters are giant planets subject to intense stellar radiation. The physical and chemical properties of their atmosphere make them the most amenable targets for atmospheric characterization. Aims. In this paper we analyze the photometry collected during the secondary eclipses of the hot Jupiter WASP-3 b by CHEOPS, TESS, and Spitzer. Our aim is to characterize the atmosphere of the pl

With increasing climate-induced stresses and ageing infrastructure worldwide, integrating sustainability into infrastructure management is essential. Structural Health Monitoring (SHM) systems provide valuable insights for assessing and maintaining the safety and integrity of ageing structures, but their implementation entails significant costs. Resources allocated to SHM could alternatively suppo

Feasibility of the promising large intelligent surface (LIS) concept, as well as its scalability, relies on the use of low-cost hardware components, raising concerns about the effects of hardware distortion. We analyze LIS systems with receive-chain (RX-chain) hardware distortion, showing how it may limit performance gains when scaling up these systems. In particular, using the memory-less polynom

Purpose: To define the curriculum content for two interactive learning courses on age-related macular degeneration (AMD): (1) an advanced course tailored for general ophthalmologists and (2) a basic course for non-ophthalmologist healthcare staff. This initiative aims to establish a national consensus on the educational framework for AMD management among general ophthalmologists in Denmark. Method

BACKGROUND: Prognostic stratification is essential for guiding treatment and follow-up in cutaneous melanoma. Previous international studies suggest that patients with localized stage IIB and IIC melanoma have poorer survival rates than those with lymph node involvement in stage IIIA. Nevertheless, Swedish guidelines still recommend less frequent follow-up for stage II than for stage III melanoma

Tattoo ink on the European market has been reported to contain many human toxicants, which has raised concerns about health effects. Clarifying the exposure distribution in the population is key to understanding potential public health implications. We investigated the prevalence of tattoos in a population-based Swedish cohort of 13 046 individuals aged 20–68 years with exposure data collected thr

Introduction: Postnatal pesticide exposure and its association with child and adolescent behavioural outcomes remain underexplored in rural agricultural settings, particularly in Africa. This study examined behavioural outcomes in relation to urinary pesticide biomarkers and contextual exposure proxies in participants from the Child health Agricultural Pesticide (CapSA) cohort, South Africa. Metho

Challenging conventional provider-oriented perspectives on older adults' spatial realities, this study explores how community-dwelling care users in Sweden manage their home environments. It investigates how older adults use the welfare system and coordinate widely available but disparate material and social resources to achieve a spatially sustainable ageing-in-place. Research on domiciliary care

We investigate public managers’ perceptions about the characteristics of global budgets and the association with perceived autonomy, using a qualitative, experiential approach. We compare and contrast differences in managers perceived autonomy associated with the use of global budgets in two large public healthcare organizations, while considering both the characteristics of other control practiceWe investigate public managers' perceptions about the characteristics of global budgets and the association with perceived autonomy, using a qualitative, experiential approach. We compare and contrast differences in managers perceived autonomy associated with the use of global budgets in two large public healthcare organizations, while considering both the characteristics of other control practice

In order to avoid extensive machine learning models selection and optimizations, Automated Machine Learning (AutoML) has arisen as a practical and efficient way to apply machine learning to many different application areas. Data poisoning is a real threat to the accuracy of machine learning models in different settings, and it has in recent research studies been shown that the usage of AutoML can

The aim of this study was to determine whether haemoglobin adducts (Hb) of hexahydrophthalic anhydride (HHPA) and HHPA-specific immunoglobulin G (IgG) can be used as biomarkers of exposure to HHPA. The exposures of HHPA in 10 workers were determined from the mean urinary hexahydrophthalic acid (HHP acid) levels (range 76-3300 nmol HHP acid mmol-1 creatinine) during a period of 4 weeks. Blood was c

Many first trimester sporadic miscarriages are unexplained and the role of environmental exposures is unknown. The present aim was to study if levels of Perfluoroalkyl substances (PFASs) in early pregnancy are associated with unexplained, sporadic first trimester miscarriage. The study was performed within the Swedish SELMA pregnancy cohort. Seventy-eight women with non-recurrent first trimester m

Combinatorial optimization provides a powerful framework for solving complex optimization problems with general-purpose solvers by modelling the problem in an abstract language. Due to breakthroughs in algorithms to solve combinatorial optimization problems in last decades, combinatorial optimization has become a valid approach to solve many real world problems efficiently. Key application areas a

BACKGROUND AND AIM[|]The incidence of skin cancer has risen sharply over the past 30 years - coinciding with the rapidly increasing tattoo trend. In Sweden, 20% of the population is tattooed. The link between tattoos and skin cancer needs to be investigated, due to the presence of carcinogenic chemicals in tattoo ink, and the lack of epidemiological studies of the association. We aimed to investig