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Anaerobic digestion of organic waste into methane and carbon dioxide (biogas) is carried out by complex microbial communities. Here, we use full-length 16S rRNA gene sequencing of 285 full-scale anaerobic digesters (ADs) to expand our knowledge about diversity and function of the bacteria and archaea in ADs worldwide. The sequences are processed into full-length 16S rRNA amplicon sequence variants
Transthoracic echocardiography (TTE) is routinely required during pre-participation screening in the presence of symptoms, family history of sudden cardiac death or cardiomyopathies <40-year-old, murmurs, abnormal ECG findings or in the follow-up of athletes with a history of cardiovascular disease (CVD). TTE is a cost-effective first-line imaging modality to evaluate the cardiac remodeling due to
PURPOSE: To compare agreement of corneal epithelium thickness (ET) between AS-OCT system (RTVue, Optovue) and AS-OCT/Placido topographer (MS-39, CSO) in eyes with different stages of keratoconus (KC), and to assess the repeatability of RTVue AS-OCT. DESIGN: Prospective reliability analysis. METHODS: KC eyes were classified into forme fruste KC (FFKC), mild, moderate, and severe KC. Agreement was e
Our current understanding of the spread and neurodegenerative effects of tau neurofibrillary tangles (NFTs) within the medial temporal lobe (MTL) during the early stages of Alzheimer’s Disease (AD) is limited by the presence of confounding non-AD pathologies and the two-dimensional (2-D) nature of conventional histology studies. Here, we combine ex vivo MRI and serial histological imaging from 25
Purpose: This study aimed to investigate the rate of re-ascent requiring re-operation after primary orchidopexy and to investigate eventual differences between the inguinal and scrotal approach as well as other potential predictors for re-ascent. Methods: A retrospective cohort study of children treated for undescended testis (UDT) with orchidopexy between 2018 and 2022 was conducted. The primary
Background: Addressing attitudes is central to achieving sexual and reproductive health and rights (SRHR) and Agenda 2030. We aimed to develop a comprehensive index to measure attitudinal support for SRHR, expanding opportunities for global trend analyses and tailored interventions. Methods: We designed a new module capturing attitudes towards different dimensions of SRHR, collected via the nation
Neurological and cardiac injuries are significant contributors to morbidity and mortality following pediatric in-hospital cardiac arrest (IHCA). Preservation of mitochondrial function may be critical for reducing these injuries. Dimethyl fumarate (DMF) has shown potential to enhance mitochondrial content and reduce oxidative damage. To investigate the efficacy of DMF in mitigating mitochondrial in
Background: Sit-to-stand (STS) is one of the most commonly performed functional movements in a child’s daily life that enables the child to perform functional activities such as independent transfer and to initiate walking and self-care. Children with cerebral palsy (CP) often have reduced STS ability. The aim of this study was to describe STS performance in a national based total population of ch
Hypothesis: Nonionic surfactants can counter the deleterious effect that anionic surfactants have on proteins, where the folded states are retrieved from a previously unfolded state. However, further studies are required to refine our understanding of the underlying mechanism of the refolding process. While interactions between nonionic surfactants and tightly folded proteins are not anticipated,
The success of social movements is highly dependent on their sustainability, as in their efforts to produce meaningful change, they inevitably encounter oppressive dominant forces. With the advent of the social media era, scholarly research on collective action has acquired an additional dimension, bringing the role of their communicative constitution to the forefront of discussions. However, a de
Over the last seventy years, most European countries have undergone one or more transitions in home heating provision. Moving first away from burning solid fuels and towards communal or individual central heating systems and now towards low carbon electric heating systems. Heating transitions are awash with personal, social and cultural complexity but tend to be simplified into grand narratives th
An increasingly competitive market, as well as transforming consumer expectations, have considerably altered the socio-economic landscape in which contemporary profit-making organizations operate. As a result, it is more difficult than ever to establish a successful and distinct brand, whilst adhering to fast-changing customer demands – especially when consumers bank on brands to fulfil a higher p
The large-scale mass mobilizations and colossal demonstrations of the last decade have shown that digital and social media platforms, globally, now play significant roles in early formation and further facilitation of activist movements, interested in progressive causes and societal changes. However, the repercussions of the very same events have also clearly shown the shortcomings of mediatized a
How to make robots safe for humans is intensely debated, within academia as well as in industry, media and on the political arena. Hardly any discussion of the subject fails to mention Isaac Asimov’s three laws of Robotics. We find it curious that a set of fictional laws can have such a strong impact on discussions about a real-world problem and we think this needs to be looked into.The probably mHow to make robots safe for humans is intensely debated, within academia as well as in industry, media and on the political arena. Hardly any discussion of the subject fails to mention Isaac Asimov’s three laws of Robotics. Asimov’s laws and the Trolley Problem are usually discussed separately but there is a connection in that the Trolley Problem poses a seemingly unsolvable problem for Asimov’s F
The mass mobilization and the collective political engagement of the Gezi Park protests of 2013 came as a surprise for many in Turkey. What was new about these large-scale demonstrations was not only the sheer number of people taking place in them (more than 3.5 million), but rather the expansive range of the protesters.This presentation looks into the Gezi events through a research question of Ho
BACKGROUND: MicroRNAs (miRNAs) are sought-after biomarkers of complex, polygenic diseases such as type 2 diabetes (T2D). Data-driven biocomputing provides robust and novel avenues for synthesizing evidence from individual miRNA seq studies.OBJECTIVE: To identify miRNA markers associated with T2D, via a data-driven, biocomputing approach on high throughput transcriptomics.MATERIALS AND METHODS: The
