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Can Artificial Intelligence Enhance Syncope Management?: A JACC: Advances Multidisciplinary Collaborative Statement : State-of-the-Art Review

Syncope, a form of transient loss of consciousness, remains a complex medical condition for which adverse cardiovascular outcomes, including death, are of major concern but rarely occur. Current risk stratification algorithms have not completely delineated which patients benefit from hospitalization and specific interventions. Patients are often admitted unnecessarily and at high cost. Artificial

The New CERN Low-energy Facilities for Neutrino Detector Tests

The beamlines at CERN's North and East Areas offer secondary beams in a wide range of momenta between 0.5 GeV/c and 400 GeV/c for fixed-target experiments as well as for test beam campaigns with a flexible configuration and variable beam composition and intensities. Recently, two new facilities for neutrino detectors tests have been established in an extension of the CERN North Area in context of

Particle identification in the low-GeV/c regime using Octafluoropropane (R-218) as Cherenkov radiator

Particle identification with threshold Cherenkov detectors, using a moderately pressurized radiating gas with an adequate refractive index, is one of the most common techniques employed in high-energy physics. However, available gases with relatively high refractive indices, that simultaneously preserve their gaseous phase at room temperature and moderate pressures, are rare. Until recently, R-12

Particle production, transport, and identification in the regime of 1-7 GeV/c

The recently constructed H4-VLE beam line, a tertiary extension branch of the existing H4 beam line in the CERN North Area, was commissioned in October 2018. The beam line was designed with the purpose of providing very low energy (VLE) hadrons and positrons to the NP-04 experiment, in the momentum range of 1-7 GeV/c. The production of these low-energy particles is achieved with a mixed hadron (pi

Commissioning Results of the Tertiary Beam Lines for the CERN Neutrino Platform Project

For many decades the CERN North Area facility at the Super Proton Synchrotron (SPS) has delivered secondary beams to various fixed target experiments and test beams. In 2018, two new tertiary extensions of the existing beam lines, designated "H2-VLE" and "H4-VLE", have been constructed and successfully commissioned. These beam lines have been designed to provide charged particles of both polaritie

Removing Biases in Communication of Severity Assessments of Intimate Partner Violence : Model Development and Evaluation

Background: To support a victim of violence and establish the correct penalty for the perpetrator, it is crucial to correctly evaluate and communicate the severity of the violence. Recent data have shown these communications to be biased. However, computational language models provide opportunities for automated evaluation of the severity to mitigate the biases. Objective: We investigated whether

Animals and the Politics of Suffering : Essays on Law, Care and Interspecies Relations

Syftet med denna sammanläggningsavhandling är att belysa de etiska, juridiska och politiska konsekvenserna av olika försök att hantera lidande hos djur orsakat av industriell djurproduktion. På basis av kvalitativa studier utförda i Danmark undersöker avhandlingen hur skötseln av lantbruksdjur förhandlas inom olika sociala domäner. För detta ändamål använder avhandlingen rättssociologiska och tvärThis compilation thesis aims to develop an understanding of the ethical, legal and political implications associated with different strategies to address the suffering of animals caused by industrialised agriculture. Based on qualitative analysis conducted in Denmark, the research explores how ethical commitment to the situation of farmed animals is negotiated across different domains. The thesis

Smart City Governance – AI Ethics in a Spatial Context : Selected Essays from 2022/2023

This brief anthology presents the basics of the interdisciplinary course called Smart City Governance – AI Ethics in a Spatial Context, given at LTH, Lund University. Furthermore, it includes three selected essays from the main assignment written by students from the class of 2022/2023. These provide with examples of the topics possible to analyse when combining engineering students from programme

Dynasties and State Formation in Early Modern Europe

In state formation research, princely houses have been a blind spot. The development of states has been discussed from many perspectives, like interstate competition, internal social conflicts, fiscal-military developments, etc., but at the centre of most European states, there was a princely house. These ruling houses have been overlooked in studies about state formation. What’s more, when discus

Building Dynasties, Shaping States : Dynasty and State Formation in Early Modern Europe

The introduction discusses the concepts of dynasty and state formation and their interrelated nature. It stresses the need to def ine the concept of dynasty as a kinship group with an acute sense of historical continuity, claiming the right to rule a certain territory and manifesting this claim in political, social and cultural ways; and the related concept of dynasty formation as the acts, consci

Dynastic Marriage Spheres in Early Modern Europe : A Comparison of the Danish Oldenburgs and Three Houses of the Empire

Princely marriages are here seen as a key component in dynasty formation and dynasty securing. The marriages of the Danish royal house and three houses of the Empire are studied for the period c. 1530–1700. Most of them took place within what can be labelled a Scandinavian-German-Lutheran marriage sphere. It was a highly hierarchized sphere with little contact between top (royal and electoral hous

Addressing the Legal Quagmire of Complementary Legal Pathways

Complementary pathways have been offered as a possible solution for facilitating legal admission of people in need of international protection. The current debates about these pathways are characterised by a conceptual and legal quagmire since various issues are invoked and conflated. The objective of this article is to dissect the relevant issues in light of the existing relevant legal frameworks

Lexikal betydelseutveckling i teori och praktik : En analys av fem definitionsformler i Svenska Akademiens ordbok och de semantiska förändringsmekanismer som de beskriver

I avhandlingen undersöks betydelsebeskrivningen i Ordbok över svenska språket utgiven av Svenska Akademien (SAOB) i ljuset av teoretisk semantik. De fem etablerade och i ordbokens definitionstext högfrekventa formlerna, eller semantiska etiketterna, "bildlig", "oegentlig", "utvidgad", "allmännare" och "överförd användning" studeras ur olika perspektiv.Frågan som ställs i avhandlingen är hur formle

Recombinant Protein Production Using the Baculovirus Expression Vector System (BEVS)

The baculovirus expression vector system (BEVS) is one of the most popular eukaryotic systems for recombinant protein production. The focus of our protein production platform is the provision of recombinant proteins for research use, where generally only small quantities are required, in the range of tens of micrograms to a few hundred milligrams. Here, we present methods that reflect our standard

Engineered allele substitution at PPARGC1A rs8192678 alters human white adipocyte differentiation, lipogenesis, and PGC-1α content and turnover

Aims/hypothesisPPARGC1A encodes peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α), a central regulator of energy metabolism and mitochondrial function. A common polymorphism in PPARGC1A (rs8192678, C/T, Gly482Ser) has been associated with obesity and related metabolic disorders, but no published functional studies have investigated direct allele-specific effects in adipocyte bi

EasyNER: A Customizable Easy-to-Use Pipeline for Deep Learning- and Dictionary-based Named Entity Recognition from Medical Text

Medical research generates a large number of publications with the PubMed database already containing >35 million research articles. Integration of the knowledge scattered across this large body of literature could provide key insights into physiological mechanisms and disease processes leading to novel medical interventions. However, it is a great challenge for researchers to utilize this informa