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The analytical and clinical validity of AI algorithms to score TILs in TNBC : can we use different machine learning models interchangeably?

Background: Pathologist-read tumor-infiltrating lymphocytes (TILs) have showcased their predictive and prognostic potential for early and metastatic triple-negative breast cancer (TNBC) but it is still subject to variability. Artificial intelligence (AI) is a promising approach toward eliminating variability and objectively automating TILs assessment. However, demonstrating robust analytical and p

Hawaiiskjortans estetik

En kulturhistorisk perspketivering med plagget Hawaiiskjortan i fokus. Dels beskrivs Hawaiiskjortan som sådan, historisk etablering, i ett internetaionellt såväl som inrikes svenskt läge; dels förs resonemang om Hawaiiskjortans symboliska och betydelseproducerande roll i populärkulturen (TV-serier, filmer, musik av olika slag).

Distributions conditioned on extrapolated events via copula and extreme value theory

In an interaction between road users, the proximity and speed are two interdependent dimensions which can be captured by a type of multivariate distribution called Copula. Copula requires all marginal distribution functions to be known. However, finding the marginal distribution of the proximity dimension is challenging, as its histogram usually contains several peaks. We partition the outcome spa

Driving Forces and Enablers for Universal Design in Urban Planning

The built environment is still, to a large extent, not accessible and usable for all. The awareness of people's different conditions and abilities sometimes seems to be far from the agenda for planning and architecture. Universal Desing (UD) is pointed out as a strategy to achieve a built environment for all people regardless of age and abilities. UD has a radical potential to bring about change a

Polarization position angle standard stars : a reassessment of θ and its variability for seventeen stars based on a decade of observations

Observations of polarization position angle (θ) standards made from 2014 to 2023 with the High Precision Polarimetric Instrument (HIPPI) and other HIPPI-class polarimeters in both hemispheres are used to investigate their variability. Multiband data were first used to thoroughly recalibrate the instrument performance by bench-marking against carefully selected literature data. A novel co-ordinate

Prevalence of valgus and varus foot deformities in 2784 children with cerebral palsy, a register-based cross-sectional study

Background: Foot deformities, such as valgus and varus in the coronal plane and equinus in the sagittal plane, are common in children with cerebral palsy (CP). The purpose of this study was to describe the prevalence of coronal plane foot deformities and their association with the Gross Motor Function Classification System (GMFCS) level, age, CP subtype, and equinus in children with CP. Methods: A

Linking Neighborhoods into Sustainable Energy Systems

Improving the energy efficiency and sustainability in the urban sector plays a vital role in the energy transition. Hence, it is important to consider promising ways to design sustainable urban energy hubs linking neighborhoods into energy systems. Improving the efficiency and sustainability of urban energy infrastructure is a process with multiple steps. This chapter presents the workflow that is

The effect of audit and feedback and implementation support on guideline adherence and patient outcomes in cardiac rehabilitation : a study protocol for an open-label cluster-randomized effectiveness-implementation hybrid trial

Background: Providing secondary prevention through structured and comprehensive cardiac rehabilitation programmes to patients after a myocardial infarction (MI) reduces mortality and morbidity and improves health-related quality of life. Cardiac rehabilitation has the highest recommendation in current guidelines. While treatment target attainment rates at Swedish cardiac rehabilitation centres is

Stakeholder interfaces for excess heat-based urban heat supply— Input from Swedish cases

Excess heat is generated from different industrial processes and from urban infrastructure (sewage water, transport, datacentres and buildings). Thirty-five percent of the European energy demand for heating and cooling could be met by excess heat. Today, however, this energy reserve is barely exploited. There are known barriers to excess heat recovery but limited information on stakeholder interac

Embodied visuo-locomotive experience analysis: immersive reality based summarisation of experiments in environment-behaviour studies

Evidence-based design (EBD) for architecture involves the study of post-occupancy behaviour of building users with the aim to provide an empirical basis for improving building performance [Hamilton and Watkins 2009]. Within EBD, the high-level, qualitative analysis of the embodied visuo-locomotive experience of representative groups of building users (e.g., children, senior citizens, individuals f

Art, aging, and artificial intelligence: Exploring age scripts in the universe of ai-generated art

This study investigates age-related biases in AI-generated art through a mixed method investigation of images of older and younger individuals. Employing 19 text prompts associated with social exclusion for older adults, we collected 465 images from an AI-art generator, MidJourney, and conducted quantitative and qualitative analyses to understand differences between age group depictions. We used A

Natural Concepts and the Economics of Cognition and Communication

This article takes a cognitive approach to natural concepts. The aim is to introduce criteria that are evaluated with respect to how they support the cognitive economy of humans when using concepts in reasoning and communicating with them. I first present the theory of conceptual spaces as a tool for expressing the criteria. Then I introduce the central idea that natural concepts correspond to con

Classroom Bullying : Understanding Bystander Reactions Across Different Bullying Types

School-based bullying is a widespread issue, but it occurs less often when bystanders defend the victims. This study examined whether type of bullying and students’ trust in their teacher’s ability to manage the class would be associated with reaction of the bystander (i.e. defending, passive, and pro-bullying). The participants were 202 ninth-grade students in Sweden, aged 15 years, who completed

Pastureland restoration is urgent for Sámi reindeer pastoralism to coexist with the forest industry and adapt to climate change in Northern Sweden

Key recommendationsPastureland restoration must be implemented to reduce dependency oncoping mechanisms such as emergency feeding, mechanized transport andintense workloads. These coping mechanisms are increasingly used to dealwith the cumulative effects of encroachments from competing land uses,predator pressure, and the impacts of climate change on snow conditions.Vigorous thinning of dense, man

Impact of Al profile in high-Al content AlGaN/GaN HEMTs on the 2DEG properties

Ultra-thin high-Al content barrier layers can enable improved gate control and high-frequency operation of AlGaN/GaN high electron mobility transistors (HEMTs) but the precise composition control is very challenging. In this work, we investigate the compositional profiles of AlxGa1−xN/GaN HEMT structures with targeted Al content in the barrier layer, x = 0.50, 0.70, and 1, and thickness in the sub

The presence, maintenance, and adaptation of Indigenous and local knowledge about climate-related hazards in Nordic contexts

The ability of people to act on their knowledge of their surrounding physical environments before, in response to, and after impactful climate-related hazards is shaped by broader environmental and socio-economic conditions. We present a multiple case study that illustrates how people from both non-Indigenous and Indigenous communities living in remote areas in the Nordic countries maintain and ad