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Twin Family Registries Worldwide: An Important Resource for Scientific Research

Published 1 September 2020 Much progress has been made in twin research since our last special issue on twin registries (Hur, Y.-M., & Craig, J. M. (2013). Twin Research and Human Genetics, 16, 1–12.). This special issue provides an update on the state of twin family registries around the world. This issue includes 61 papers on twin family registries from 25 countries, of which 3 describe consorti

https://www.lupop.lu.se/article/twin-family-registries-worldwide-important-resource-scientific-research-0 - 2025-02-07

Communicating science in an age of on-screen reading: taking a page from journalism

Published 2 September 2020 With the increasing move to publish manuscripts online, the science community needs to consider what effect this will have on their ability to communicate findings effectively to not only the science community but to the public as well. Online manuscripts are not a new concept. The increasing trend towards online use will be seamless for many. Yet, with information readi

https://www.lupop.lu.se/article/communicating-science-age-screen-reading-taking-page-journalism - 2025-02-07

Statistical inference in matched case–control studies of recurrent events

Published 2 September 2020 The concurrent sampling design was developed for case–control studies of recurrent events. It involves matching for time. Standard conditional logistic-regression (CLR) analysis ignores the dependence among recurrent events. Existing methods for clustered observations for CLR do not fit the complex data structure arising from the concurrent sampling design. Read more at

https://www.lupop.lu.se/article/statistical-inference-matched-case-control-studies-recurrent-events - 2025-02-07

Data Resource Profile: The Valencia Health System Integrated Database (VID)

Published 3 September 2020 The Valencia Health System Integrated Database (VID) is a set of multiple, public, population-wide electronic databases for the Valencia Region, the fourth most populated Spanish region, with ∼5 million inhabitants and an annual birth cohort of 48 000 newborns, representing 10.7% of the Spanish population and around 1% of the European population. Read more at https://aca

https://www.lupop.lu.se/article/data-resource-profile-valencia-health-system-integrated-database-vid - 2025-02-07

Data Resource Profile: The Philippine National Nutrition Survey (NNS)

Published 3 September 2020 The Philippine National Nutrition Survey (NNS) is the official nationwide survey on nutritional status, diet and other lifestyle-related risk factors for noncommunicable diseases. The NNS is designated to generate critical data for decision making by the government and the private sector in the Philippines. Data from the NNS have been used as a reference for formulating

https://www.lupop.lu.se/article/data-resource-profile-philippine-national-nutrition-survey-nns - 2025-02-07

Cohort Profile: The Maule Cohort (MAUCO)

Published 4 September 2020 The Maule Cohort (MAUCO) is the first prospective population-based cohort of cardiovascular disease (CVD) and cancer in central Chile. The rationale for this cohort is based on the social, environmental and health characteristics of an under-studied rural population at high risk for chronic diseases. Read more at https://academic.oup.com/ije/article/49/3/760/5807634

https://www.lupop.lu.se/article/cohort-profile-maule-cohort-mauco - 2025-02-07

Cohort Profile: The Kaloleni/Rabai Community Health and Demographic Surveillance System

Published 4 September 2020 In many resource-constrained settings, availability of reliable vital statistics and health information is limited by lack of proper system for civil registration and health information. This is further limited by the fact that the majority of population health events, such as births, morbidity and mortality, occur outside the reach of these systems. In particular, obtai

https://www.lupop.lu.se/article/cohort-profile-kalolenirabai-community-health-and-demographic-surveillance-system - 2025-02-07

Cohort Profile: The Finnish Gestational Diabetes (FinnGeDi) Study

Published 5 September 2020 The Finnish Gestational Diabetes (FinnGeDi) study is a multicentre study that considered Finnish women who gave birth in 2009–12, as well as their children and the children’s fathers. The study period was after the introduction of new Finnish national comprehensive screening guidelines for gestational diabetes mellitus (GDM). The study consisted of two arms: a prospectiv

https://www.lupop.lu.se/article/cohort-profile-finnish-gestational-diabetes-finngedi-study - 2025-02-07

Daily School Physical Activity Improves Academic Performance

Published 5 September 2020 Physical activity (PA) may improve brain development, cognition, concentration and academic performance. In this prospective controlled intervention study, we increased the level of PA in 338 children aged 6–8 years at study start, from the Swedish standard of 60 min per week to 200 min per week (40 min daily). The intervention continued in all nine compulsory school yea

https://www.lupop.lu.se/article/daily-school-physical-activity-improves-academic-performance - 2025-02-07

Poor psychological health and 5-year suicide mortality: A population-based prospective cohort study.

Published 6 September 2020 The objective was to investigate associations between the General Health Questionnaire with twelve sub-items (GHQ-12) and prospective five-year suicide mortality. The two commonly used GHQ-12 cut-offs (2/3 and 3/4) were analyzed. METHOD:The 2008 public health survey, which was conducted in the autumn of 2008 in Scania, southern Sweden, is based on a postal questionnaire

https://www.lupop.lu.se/article/poor-psychological-health-and-5-year-suicide-mortality-population-based-prospective-cohort-study - 2025-02-07

Per- and Polyfluoroalkyl Substances in Early Pregnancy and Risk for Preeclampsia: A Case-Control Study in Southern Sweden

Published 6 September 2020 Preeclampsia is one of the most common causes of perinatal and maternal morbidity/mortality. One suggested environmental risk factor is exposure to endocrine-disrupting pollutants such as per- and polyfluoroalkyl substances (PFAS). The present case-control study in southern Sweden aims to investigate the hypothesized association between serum concentrations of PFAS in ea

https://www.lupop.lu.se/article/and-polyfluoroalkyl-substances-early-pregnancy-and-risk-preeclampsia-case-control-study-southern - 2025-02-07

Invasive infections with Fusobacterium necrophorum including Lemierre's syndrome: an 8-year Swedish nationwide retrospective study

Published 7 September 2020 We aimed to evaluate the nationwide incidence and a potential increase in invasive infections with Fusobacterium necrophorum. Secondly, we aimed to describe epidemiology, clinical characteristics and outcomes for the different presentations: Lemierre's syndrome (LS), invasive head and neck-infection without LS and invasive non-head and neck-infection. Read more at https:

https://www.lupop.lu.se/article/invasive-infections-fusobacterium-necrophorum-including-lemierres-syndrome-8-year-swedish-nationwide - 2025-02-07

Calculating the Starting Age for Screening in Relatives of Patients With Colorectal Cancer Based on Data From Large Nationwide Data Sets

Published 7 September 2020 Although colorectal cancer (CRC) screening guidelines acknowledge the need for earlier screening for high-risk individuals, such as those with family history of CRC, there is limited information on how many years earlier these high-risk individuals should be screened; current practice is based on weak evidence. We aimed to provide risk-adapted recommendations on the star

https://www.lupop.lu.se/article/calculating-starting-age-screening-relatives-patients-colorectal-cancer-based-data-large-nationwide - 2025-02-07

Fetal Programming of Semen Quality (FEPOS) Cohort – A DNBC Male-Offspring Cohort

Published 8 September 2020 Prenatal exposures may contribute to male infertility in adult life, but large-scale epidemiological evidence is still lacking. The Fetal Programming of Semen quality (FEPOS) cohort was founded to provide means to examine if fetal exposures can interfere with fetal reproductive development and ultimately lead to reduced semen quality and reproductive hormone imbalances i

https://www.lupop.lu.se/article/fetal-programming-semen-quality-fepos-cohort-dnbc-male-offspring-cohort - 2025-02-07

Multiple sclerosis among first‐ and second‐generation immigrant groups in Sweden

Published 8 September 2020 We included adults aged 18 years and older in Sweden in first‐generation (n = 6 042 891) and second‐generation (n = 4 860 469) sub‐studies. MS was defined via two diagnoses in the Swedish National Patient Register. MS risk was estimated by Cox regression, with hazard ratios (HRs) and 95% confidence intervals (CI), in different immigrant groups, using Swedish‐born as refe

https://www.lupop.lu.se/article/multiple-sclerosis-among-first-and-second-generation-immigrant-groups-sweden - 2025-02-07

Geographical and sociodemographic differences in discontinuation of medication for Chronic Obstructive Pulmonary Disease – A Cross-Classified Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA)

Published 9 September 2020 While discontinuation of COPD maintenance medication is a known problem, the proportion of patients with discontinuation and its geographical and sociodemographic distribution are so far unknown in Sweden. Therefore, we analyse this question by applying an innovative approach called multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA). Rea

https://www.lupop.lu.se/article/geographical-and-sociodemographic-differences-discontinuation-medication-chronic-obstructive - 2025-02-07

Global systematic review of primary immunodeficiency registries

Published 9 September 2020 During the last 4 decades, registration of patients with primary immunodeficiencies (PID) has played an essential role in different aspects of these diseases worldwide including epidemiological indexes, policymaking, quality controls of care/life, facilitation of genetic studies and clinical trials as well as improving our understanding about the natural history of the d

https://www.lupop.lu.se/article/global-systematic-review-primary-immunodeficiency-registries - 2025-02-07

Research Services presents: Meet the Funders

Published 2 September 2020 Research Services is pleased to announce a pair of webinars on research funding from some of the biggest funders in Sweden. These webinars will give you a chance to hear straight from the funders about their schemes and funding philosophy, and they will also answer your questions directly. The webinars are open to all researchers at Lund, and no prior knowledge of the fu

https://www.lupop.lu.se/article/research-services-presents-meet-funders - 2025-02-07

Population Registry of Esophageal and Stomach Tumours in Ontario (PRESTO): protocol for a multicentre clinical and pathological database including 25 000 patients

Published 10 September 2020 Oesophagogastric cancers carry a high mortality, economic burden and rising incidence. There is a need to monitor and improve care for this disease. Pathologic information is a cornerstone of cancer diagnosis, treatment and prognosis. Few population-based studies combine pathology information and clinical outcomes. The objective of this study is to develop a clinical an

https://www.lupop.lu.se/article/population-registry-esophageal-and-stomach-tumours-ontario-presto-protocol-multicentre-clinical-and - 2025-02-07