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The distributed national research infrastructure Protein Production Sweden (PPS), where LP3 is included, met for its third annual staff retreat at Skeppsviks Herrgård near Umeå. The 23 staff researchers of PPS attending used the two day meeting to discuss and reflect about the first 2.5 years of PPS operations supporting more than 450 user projects so far, present new method developments in PPS an

https://www.lp3.lu.se/article/lp3-participated-annual-pps-retreat-umea - 2025-11-07

LP3 is one of three major university research infrastructures selected as university platforms by our rector. The appointment signals that these research infrastructures have high strategic importance for the entire university. The appointments are based on a number of criteria, for example the research infrastructures must have contributed to excellent research, offered broad accessibility for us

https://www.lp3.lu.se/article/lund-university-has-selected-lp3-become-university-platform - 2025-11-07

LP3 now has a demo unit of Fidabio (Fida Neo instrument) for Flow Induced Dispersion Analysis for protein sample quality, which is available for evaluation purposes the next 3 months. The analysis of sample gives an indication of the protein's health, oligomeric state/complex formation, if its monodisperse or aggregated and buffer compatibility etc. If you have any sample that you would like to kn

https://www.lp3.lu.se/article/free-testing-flow-induced-dispersion-analysis-now-lp3 - 2025-11-07

Four of LP3’s staff participated in the first SciLifeLab Lund retreat in Båstad, 14 to 15th November 2024 with the theme: “Achieving Excellence Together”. The retreat was focused on giving the staff from all SciLifeLab site platforms the opportunity to get to know each other through presentations, group exercises and discussions. LP3 presented it’s capabilities in Lund, but also the national resea

https://www.lp3.lu.se/article/lp3-first-scilifelab-lund-retreat - 2025-11-07

The Swedish NMR Centre in Gothenburg will host a workshop on cell-free protein synthesis, with special focus on applications in NMR spectroscopy. The workshop, which is held in Gothenburg 21-23 Jan 2025 will entail both lectures and practical wet lab work. The idea is that participants bring their own plasmid construct for expression, with possible isotope labelling to judge the outcome with 2D NM

https://www.lp3.lu.se/article/cell-free-protein-synthesis-workshop-january-2025 - 2025-11-07

SciLifeLab Lund, which Lp3 is part of, arranges interesting seminars with presentations of its different units and local core facilities together with user presentations. So please take the opportunity to learn more of our different services which could be useful in you research. The SciLifeLab seminars are all given at 3 pm (15.00) in Belfragesalen at BMC D15, Klinkgatan 32, Lund. Most welcome! F

https://www.lp3.lu.se/article/welcome-scilifelab-seminars - 2025-11-07

LP3 was presented at the yearly meeting for MAX IV synchrotron users held in January 2025. Dr. Celeste Sele presented two posters about LP3's capabilities within protein crystallisation/biophysics and structure determination as well as protein production within the national research infrastructure Protein Production Sweden (PPS, see external homepage)

https://www.lp3.lu.se/article/lp3-36th-max-iv-user-meeting - 2025-11-07

In the very last number of LUM, there was a popular science presentation of LP3 and our work. "LP3 has since the start in 2012, produced proteins for around 300 research projects - from drug development to sustainable chemical processes"Read the full article (in Swedish) here on the Lund University Web.

https://www.lp3.lu.se/article/article-about-lp3-lund-university-magazine - 2025-11-07

LP3 will provide capabilities within protein production, biophysical characterization and protein structure determination to help VIGILANT achieve its goals. VIGILANT: Targeting ER Import And Activation Of Viral Glycoproteins: Towards Broad-Spectrum AntiviralsLP3 will provide capabilities within protein production, biophysical characterization and protein structure determination to a new EU resear

https://www.lp3.lu.se/article/lp3-collaborates-new-eu-research-project-vigilant - 2025-11-07

LP3 attended the 28th Swedish Conference on Macromolecular Structure & Function (SWEPROT) in Tällberg last weekend and presented our capabilities through several posters. Several PPS team members visited the meeting with around 130 other participants from the Swedish protein science community.More info on SWEPROT is found on the homepage (external).

https://www.lp3.lu.se/article/lp3-tallberg-conference-2025 - 2025-11-07

Several LP3 members presented our capabilities with a poster at the first conference held in Linxs new facilities. The conference was held to celebrate the opening of the LINXS at Brunnshög in the newly build Loop (more info here on Linxs homepage). Several staff members of PPS visited the opening with many national and international participants interested in X-ray and neutron applications.

https://www.lp3.lu.se/article/lp3-inagural-conference-new-linxs - 2025-11-07

More than a hundred participants from all over Europe attended the three-day program with workshops, lectures and vendor presence to share knowledge in the field of protein production and purification. The P4EU (Protein Production and Purification Partnership in Europe; see external homepage) is a professional network, whose members engage in various aspects of protein expression, purification and

https://www.lp3.lu.se/article/lp3-staff-co-organised-21st-p4eu-meeting-gothenburg-sweden-25-27th-august-2025 - 2025-11-07

The distributed national research infrastructure Protein Production Sweden (PPS), where LP3 is included, met for its fourth annual staff retreat at LINXS in Lund. The 27 staff researchers of PPS attending used the three-day meeting to discuss and reflect on the first 3.5 years of PPS operations delivering more than 1000 protein batches so far, present new method developments in PPS and plan furthe

https://www.lp3.lu.se/article/lp3-organized-fourth-pps-staff-retreat-lund - 2025-11-07

An international collaboration between the Lund Protein Production Platform (LP3), the UCL School of Pharmacy and ESS, through its DEMAX platform, has initiated biophysical and structural studies of three non-structural proteins from the novel coronavirus, SARS CoV-2, the causative agent of COVID-19. Recently we managed to solve the structure of one of these proteins, Nsp10, by using the BioMAX be

https://www.lp3.lu.se/article/collaborative-research-project-corona-virus-proteins - 2025-11-07

Results from the collaborative corona virus protein research project involvning Lund Protein Production Platform (LP3), the UCL School of Pharmacy and ESS, through its DEMAX platform have been published in the International Journal of Molecular Sciences.

https://www.lp3.lu.se/article/results-collaborative-corona-virus-protein-research-project-published - 2025-11-07

LP3 activities will be limited during the summer, especially in July and early August. In the meantime, here’s some recommended summer reading:

https://www.lp3.lu.se/article/recommended-summer-reading - 2025-11-07

FragMAX, a project run in collaboration between LP3, MAXIV, Astra Zeneca and SARomics Biostructures, has been awarded funding from the Swedish Research Council. The project aims to establish a fragment based screening facility, enabling scientists and small companies to screen low molecular weight fragments for binding to target proteins using X-ray crystallography.Read more about the FragMAX proj

https://www.lp3.lu.se/article/fragmax-awarded-funding-swedish-research-council - 2025-11-07

LP3 was successful in its application for renewal of beamtime access at BioMAX (the X-ray macromolecular crystallography beamline of MAX IV). The protein structure pipeline at LP3 is now established. Users can get their protein samples crystallised and the resulting crystals can on a regular basis be evaluated for diffraction and data can be collected. Processing of X-ray data and solving structur

https://www.lp3.lu.se/article/renewal-beamtime-access-biomax-and-allocated-time-scilifelab-cryo-em-facility - 2025-11-07

A team from the Lund Protein Production Platform, Karolinska Institute, and the European Spallation Source have published an optimised approach to high-yield protein deuteration at low cost, for neutron protein crystallography in Archives of Biochemistry and Biophysics (external website). 

https://www.lp3.lu.se/article/more-less-low-cost-high-yield-protein-deuteration-neutron-crystallography - 2025-11-07

The baculovirus-insect cell expression system has become one of the most widely used eukaryotic expression systems for heterologous protein production in many laboratories. To date, limited data has been presented in the literature to benchmark the protocols used for baculovirus vectors, and this study facilitates the selection of a system for optimal production of target proteins. The benchmarkin

https://www.lp3.lu.se/article/baculovirus-driven-protein-expression-insect-cells-benchmarking-study - 2025-11-07