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Landscape of Cardiovascular Device Registries in the United States

Published 30 November 2019 Regulators increasingly rely on registries for decision making related to high‐risk medical devices in the United States. However, the limited uniform standards for registries may create substantial variability in registry implementation and utility to regulators. We surveyed the current landscape of US cardiovascular device registries and chart the extent of inconsisten

https://www.lupop.lu.se/article/landscape-cardiovascular-device-registries-united-states - 2025-03-16

Lessons learned in the use of clinical registry data in a multi-centre prospective study: the Pediatric Heart Network Residual Lesion Score Study

Published 30 November 2019 Survey response rate was 98% (54/55). Overall, 57% perceived that using registry data saved research staff time in the current study, and 74% perceived that it would save time in future studies; 55% noted significant upfront time in developing a methodology for extracting registry data. Survey recommendations included simplifying data extraction processes and tailoring t

https://www.lupop.lu.se/article/lessons-learned-use-clinical-registry-data-multi-centre-prospective-study-pediatric-heart-network - 2025-03-16

Reflection on modern methods: calculating a sample size for a repeatability sub-study to correct for measurement error in a single continuous exposure

Published 1 December 2019 Using a continuous exposure variable that is measured with random error in a univariable linear regression model leads to regression dilution bias: the observed association between the exposure and outcome is smaller than it would be if the true value of the exposure could be used. A repeatability sub-study, where a sample of study participants have their data measured ag

https://www.lupop.lu.se/article/reflection-modern-methods-calculating-sample-size-repeatability-sub-study-correct-measurement-error - 2025-03-16

Methodological point on mediation analysis

Published 1 December 2019 Recently, King et al.1 assessed the effect of disability on mental health through bullying in adolescents using a causal mediation analysis method developed by Valeri and VanderWeele2 in which exposure–mediator interactions are allowed. In the latter method, one can only handle time-fixed exposure and mediator, and, for this reason, the authors only used the exposure in w

https://www.lupop.lu.se/article/methodological-point-mediation-analysis - 2025-03-16

Using registries for research in CF. How can we be sure about the outputs?

Published 2 December 2019 In healthcare, we have kept notes on people with diseases for over 4000 years. These have been a combination of subjective commentary and objective measurement. In the past 30 years recording data on patients has been systematised through disease registries and electronic patient records (EPR). We now have extensive registries in many diseases with robust cross-sectional

https://www.lupop.lu.se/article/using-registries-research-cf-how-can-we-be-sure-about-outputs - 2025-03-16

Nytt avtal med Elsevier

Published 28 November 2019 Bibsamkonsortiet tecknar ett läs- och publiceringsavtal med det vetenskapliga förlaget Elsevier. Det innebär att svenska forskare nu åter får tillgång till förlagets drygt två tusen tidskrifter. Dessutom kommer alla svenska forskningsartiklar kunna publiceras omedelbart öppet tillgängligt (open access). Läs mer här.

https://www.lupop.lu.se/article/nytt-avtal-med-elsevier - 2025-03-16

FORMAS urgent grants

Published 12 December 2017 Today, FORMAS announced the urgent grants for 2018 Last day of application: Any time during the year, until 08/11/2018Day of decision: Continuously during the year, last day of decision is 15/01/2019An urgent grant application can be submitted for any scientific discipline; the humanities, natural sciences, social sciences and technological sciences, and may also include

https://www.lupop.lu.se/article/formas-urgent-grants - 2025-03-16

Characterizing Short-Term Jobs in a Population-Based Study

Published 3 December 2019 Work histories generally cover all jobs held for ≥1 year. However, it may be time and cost prohibitive to conduct a detailed exposure assessment for each such job. While disregarding short-term jobs can reduce the assessment burden, this can be problematic if those jobs contribute important exposure information towards understanding disease aetiology. New publication in A

https://www.lupop.lu.se/article/characterizing-short-term-jobs-population-based-study - 2025-03-16

For a sound use of health care data in epidemiology: evaluation of a calibration model for count data with application to prediction of cancer incidence in areas without cancer registry

Published 3 December 2019 There is a growing interest in using health care (HC) data to produce epidemiological surveillance indicators such as incidence. Typically, in the field of cancer, incidence is provided by local cancer registries which, in many countries, do not cover the whole territory; using proxy measures from available nationwide HC databases would appear to be a suitable approach to

https://www.lupop.lu.se/article/sound-use-health-care-data-epidemiology-evaluation-calibration-model-count-data-application - 2025-03-16

Compared with whom? Reference groups in socio-economic comparisons and self-reported health in 34 countries

Published 4 December 2019 The association between socio-economic position and health is believed to be mediated, in part, by psycho-social comparison of one’s situation with that of others. But with whom? Possibilities include family, friends, elites, or even those in other countries or in previous times. So far, there has been almost no research on whether the reference point matters. New publica

https://www.lupop.lu.se/article/compared-whom-reference-groups-socio-economic-comparisons-and-self-reported-health-34-countries - 2025-03-16

The ESC-EORP EURO-ENDO (European Infective Endocarditis) registry

Published 4 December 2019 The European Society of Cardiology (ESC) EURObservational Research Programme (EORP) European Endocarditis (EURO-ENDO) registry aims to study the care and outcomes of patients diagnosed with infective endocarditis (IE) and compare findings with recommendations from the 2015 ESC Clinical Practice Guidelines for the management of IE and data from the 2001 Euro Heart Survey.

https://www.lupop.lu.se/article/esc-eorp-euro-endo-european-infective-endocarditis-registry - 2025-03-16

Weight and height separated provide better understanding than BMI on the risk of revision after total knee arthroplasty: report of 107,228 primary total knee arthroplasties from the Swedish Knee Arthroplasty Register 2009–2017

Published 5 December 2019 Obesity defined as increased BMI is commonly associated with higher revision rates following total knee arthroplasty (TKA). We examined the effect of BMI on the rate of revision after TKA, for both infection and other reasons, and analyzed weight and height separately to provide better understanding of the risk profile. New publication in Journal Acta Orthopaedica

https://www.lupop.lu.se/article/weight-and-height-separated-provide-better-understanding-bmi-risk-revision-after-total-knee - 2025-03-16

Genetic instrumental variable analysis: time to call mendelian randomization what it is. The example of alcohol and cardiovascular disease

Published 5 December 2019 In recent years, epidemiologists have increasingly sought to employ genetic data to identify ‘causal’ relationships between exposures of interest and various endpoints – an instrumental variable approach sometimes termed Mendelian randomization. However, this approach is subject to all of the limitations of instrumental variable analysis and to several limitations specifi

https://www.lupop.lu.se/article/genetic-instrumental-variable-analysis-time-call-mendelian-randomization-what-it-example-alcohol-and - 2025-03-16

Midlife physical activity is associated with lower incidence of vascular dementia but not Alzheimer’s disease

Published 6 December 2019 Physical activity might reduce the risk of developing dementia. However, it is still unclear whether the protective effect differs depending on the subtype of dementia. We aimed to investigate if midlife physical activity affects the development of vascular dementia (VaD) and Alzheimer’s disease (AD) differently in two large study populations with different designs. New p

https://www.lupop.lu.se/article/midlife-physical-activity-associated-lower-incidence-vascular-dementia-not-alzheimers-disease - 2025-03-16

How Independent Are “Independent” Effects? Relative Risk Estimation When Correlated Exposures Are Measured Imprecisely

Published 6 December 2019 A relative risk estimate which relates an exposure to risk of disease will tend to be estimated too close to unity if that exposure is subject to random measurement error or intra-subject variability. New publication in International Journal of Epidemiology

https://www.lupop.lu.se/article/how-independent-are-independent-effects-relative-risk-estimation-when-correlated-exposures-are - 2025-03-16

Förändringar i Socialstyrelsens klassifikationer

Published 5 December 2019 Från den 1/1 2020 sker en del ändringar i Socialstyrelsens klassifikationer vilket är viktigt för dig att veta som använder klassifikationer vid bl.a. statistik-, analys- och registerarbete. 1)      https://www.socialstyrelsen.se/utveckla-verksamhet/e-halsa/klassificering-och-koder/senaste-uppdateringar/  (Via denna länk hittas ändringar fr.o.m. 2020 i Pdf-format till kla

https://www.lupop.lu.se/article/forandringar-i-socialstyrelsens-klassifikationer - 2025-03-16

The importance of clinical registries

Published 7 December 2019 Griffen and colleagues article on extrapolating information from national registries showcases the importance of clinical health registries in identifying relationships between factors that can lead to adverse health outcomes. As discussed by the authors, how this adds to the body of evidence is that it is identified that this population group (patients with alcohol consu

https://www.lupop.lu.se/article/importance-clinical-registries - 2025-03-16