The concept that tumor-initiating cells can co-opt the self-renewal program of endogenous stem cells as a means of enforcing their unlimited proliferative potential is widely accepted, yet identification of specific factors that regulate self-renewal of normal and cancer stem cells remains limited. Using a comparative transcriptomic approach, we identify ZNF521/Zfp521 as a conserved hematopoietic

Background and purpose — Analysis of the revision-free survival of knee and hip prostheses has traditionally been performed using Kaplan–Meier analysis and Cox regression. The competing risk problem that is related to patients who die during follow-up has recently been increasingly discussed, not least with regard to the problem of choosing a suitable statistical method for the analysis. We compar

‘Collective Autonomy in the European Union’ explores the question of collective autonomy by investigating the relationship between collective bargaining and legal regulation and its current evolution in the national contexts and in the EU internal market. The thesis aims at achieving a comprehensive understanding of the notion, function and exercise of collective autonomy and collective bargaining‘Collective Autonomy in the European Union’ explores the question of collective autonomy by investigating the relationship between collective bargaining and legal regulation and its current evolution in the national contexts and in the EU internal market. The thesis aims at achieving a comprehensive understanding of the notion, function and exercise of collective autonomy and collective bargaining

The pulp and paper industry is among the world most important industrial sectors. At present it focuses on the production of cellulose pulp fibers and electricity but transforming pulp mills into biorefineries can reduce the use of fossil fuel resources. Adjusting the processes and converting lignocellulosic materials into new environmental friendly products will enable the production of biochemic

There is a strong industrial drive to use cloud computing technologies and concepts for providing timing sensitive services in the networking domain since it would provide the means to share the physical resources among multiple users and thus increase the elasticity and reduce the costs. In this work, we develop a mathematical model for user-stateless virtual network functions forming a forwardin

Stads- och trafikplanering är komplext och som konstaterades inledningsvis i denna rapport har cyklingen generellt sett minskat i Sverige och svenska städer trots målsättningar och ambitioner om motsatsen. En möjlig orsak till detta är att det dels är svårt att skapa sig en samlad överblick över vilka faktorer som påverkar valet att cykla, dels är svårt att skapa sig en samlad överblick över hur d

During the past few decades systemic corruption has come to be seen as a significant factor which hinders socio-economic development, posing a serious threat to the political, economic and social well-being of many developing and transition countries. Under conditions of systemic corruption, many institutions, rules and norms of behaviour have become adapted to a corrupt modus operandi. Public off

The paper compares the broad outlines of decentralization taking place in India, dating from the last decade of the past century, with that of Indonesia in the first decades of the present one. It focuses on the generally acknowledged least successful of reforms, namely that of public administration. Public administration tends to reflect the respective country’s prevailing norms. The paper opens

An actor perspective within a moralistic approach to corruption in india and Southeast Asia contrasts to a (Weberian) institutional one. This emphasizes local values which help explain apparent lack of social constraints to everyday corrupt practices as bribery. In Karnataka the approach indicates that status and power within one’s own community gained by amassing wealth however acquired overrides

India is a country characterized by multi-layered diversity and cultural heterogeneity where different types of inequalities and poverty have always been a fact of life. Since independence in 1947, she followed a development policy based on interventionist central planning and import substitution with the objective of reducing inequality and poverty. Policymakers adopted a middle path in which inc

The article focuses on the individual actor’s choice as weather to condone or condemn corruption in their respective countries of India and Indonesia. Given the influence of traditions, the choice is rational in that it must be seen through the lens of cultural values, which by definition are seldom Weberian. Following the sketched illustration, the dichotomy between systems of values, the paper p

During the 1970s, vocabulary knowledge was a central topic within the field of Swedish sociolinguistics, often discussed from a democratic point of view focusing on inclusion and accessibility in the society. This study links up to this tradition by reporting a survey of how the vocabulary knowledge has changed over time in Sweden, building on data from theSwedish Scholastic Aptitude Test (SweSAT)During the 1970s, vocabulary knowledge was a central topic within the field of Swedish sociolinguistics, often discussed from a democratic point of view focusing on inclusion and accessibility in the society. This study links up to this tradition by reporting a survey of how the vocabulary knowledge has changed over time in Sweden, building on data from theSwedish Scholastic Aptitude Test (SweSAT)

Cloud computing technology provides the means to share physical resources among multiple users and data center ten- ants by exposing them as virtual resources. There is a strong industrial drive to use similar technology and concepts to provide timing sensitive services. One such is virtual net- working services, so called services chains, which consist of several interconnected virtual network fu

Organisations have flattened and increasingly rely on teamwork. Therefore, colleagues play an increasingly important role in stimulating employee motivation. Adopting Self-Determination Theory as a guiding framework, the aim of this field experiment was to examine whether team members can be trained in supporting each other's basic psychological needs for autonomy, competence, and relatedness and,

Background. S100β has been suggested as a marker of brain damage after cardiac operation. The aim of this study was to characterize the early S100β release in detail and relate it to neuropsychological outcome. Methods. Three groups of patients were investigated. All patients underwent coronary artery bypass surgery (CABG) with extracorporeal circulation. In group A, 110 patients had sampling of S

Background. S100 protein has been suggested to be a serum marker for cerebral complications after cardiac operation and extracorporeal circulation. The aim of this study was to characterize the S100 release pattern after extracorporeal circulation in 515 consecutive patients undergoing coronary artery bypass grafting. Methods. Clinical variables and outcome were prospectively registered. The cereb