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Effects of Sex on Early Outcome following Repair of Acute Type A Aortic Dissection : Results from the Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD)

Background Female sex is known to have increased perioperative mortality in cardiac surgery. Studies reporting effects of sex on outcome following surgical repair for acute Type A aortic dissection (ATAAD) have been limited by small cohorts of heterogeneous patient populations and have shown diverging results. This study aimed to compare perioperative characteristics, operative management, and pos

Mayr Versus Woese : Akaryotes and Eukaryotes

In 1998, on the brink of a great public effort that by now has delivered the sequences of thousands of genomes and has annotated these genomes by translating tens of thousands of 3D protein domain structures from their coding sequences, Ernst Mayr and Carl Woese engaged in a debate. At issue were the virtues of phenotypic contra genotypic approaches to phylogeny and taxonomy. Though not conclusive

Applying the ecosystem model in a new context? The case of business incubation in Oman

This paper studies entrepreneurship ecosystem development in a context little discussed in the extant literature to date: Oman. Specifically, it focuses on business incubation (BI) initiatives as a policy tool for developing the local, regional, and national systems of supporting entrepreneurship and SME growth. Although BI’s are a popular policy measure for ecosystem development, spreading global

Proteins linked to atherosclerosis and cell proliferation are associated with the shrunken pore syndrome in heart failure patients

PURPOSE: The "Shrunken pore syndrome" (SPS) is characterized by a difference in renal filtration between cystatin C and creatinine, resulting in a low eGFRcystatinC /eGFRcreatinine -ratio. Studies have demonstrated a high risk for cardiovascular morbidity and mortality for patients with SPS. In this discovery study, we explored associations between SPS and proteins implicated in cardiovascular dis

Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers

Squamous cell carcinomas (SqCC) of the aerodigestive tract have similar etiological risk factors. Although genetic risk variants for individual cancers have been identified, an agnostic, genome-wide search for shared genetic susceptibility has not been performed. To identify novel and pleotropic SqCC risk variants, we performed a meta-analysis of GWAS data on lung SqCC (LuSqCC), oro/pharyngeal SqC

Predicting neurological outcome after out-of-hospital cardiac arrest with cumulative information; development and internal validation of an artificial neural network algorithm

Background: Prognostication of neurological outcome in patients who remain comatose after cardiac arrest resuscitation is complex. Clinical variables, as well as biomarkers of brain injury, cardiac injury, and systemic inflammation, all yield some prognostic value. We hypothesised that cumulative information obtained during the first three days of intensive care could produce a reliable model for

Spectroscopic characterization of electronic structures of ultra-thin single crystal La0.7Sr0.3MnO3

We have successfully fabricated high quality single crystalline La0.7Sr0.3MnO3 (LSMO) film in the freestanding form that can be transferred onto silicon wafer and copper mesh support. Using soft x-ray absorption (XAS) and resonant inelastic x-ray scattering (RIXS) spectroscopy in transmission and reflection geometries, we demonstrate that the x-ray emission from Mn 3s-2p core-to-core transition (3

Room temperature multiferroic PZTFT thin films

Multiferroic materials have shown significant potential for next generation nanoelectronic and multifunctional devices due to their coexistent order parameters and versatile tunabilities. Nevertheless, the selectivity of the room temperature multiferroics is extremely limited. In this manner, single-phase solid-solution-type multiferroics that are composed by distinct oxides exhibiting either ferr

Pancreatic cancer is suppressed by fibroblast-derived collagen I

Clinical implementation of anti-stromal therapies in pancreatic cancer has been delayed by unanticipated tumor-restraining properties of the desmoplastic stroma. In confronting these challenges, Chen et al. demonstrate in this issue of Cancer Cell that fibroblast-specific deletion of collagen I, in the background of oncogenic Kras-induced spontaneous murine pancreatic ductal adenocarcinoma, enhanc

The beetle (Coleoptera) fauna of an abandoned exercise field in south Sweden

Species diversity and composition of the Coleoptera (beetle) fauna in a recently abandoned military exercise field in south Sweden was studied during sixteen years. The sixteen square km large area contained deciduous wood (mainly Fagus and Carpinus), shrubland, open ground, and pastures. Beetles were captured using three different methods: pitfall trapping, striking of foliage, and sweep bag coll

Experiences of Supplemental Instruction at Two Scandinavian Universities

The topic of this article is experiences regarding Supplemental Instruction (SI) at two Scandinavian Universities. The purpose is to describe the basis for and implementation of SI programmes at the two universities, and to compare their similarities and differences. Our research questions were as follow: What were the reasons and background for implementing SI? How was the SI programme founded, p

Enhancing Employability Skills Through Being an SI-PASS Leader

The present survey study focuses on potential benefits of the SI-PASS experience for former Leaders in their professional life after graduating from higher education. This topic has received little attention previously with the few studies made being limited in number of participants and different in approaches used and in questions asked. The present survey was sent to 279 former SI-PASS Leaders

Supplemental Instruction (SI) in Europe: An Overview of Current SI Programmes

Supplemental Instruction (SI) is a 47-year old proven peer-learning model that addresses student engagement, performance and retention as well as the transition to Higher Education (HE). SI was developed at the University of Missouri Kansas City in the US and has received wide recognition. Today the method has practitioners all over the United States as well as in several other countries around th