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Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen hos västerländska kvinnor. I Sverige kommer var tionde kvinna att drabbas av bröstcancer, vilket motsvarar drygt 5000 kvinnor om året. Dödligheten i bröstcancer är 30%. Detta innebär att en tredjedel av de som drabbas kommer att dö av sin sjukdom. Det är dock inte själva tumören i bröstet som dödar eftersom denna i princip alltBreast cancer is one of the most common cancer forms in the industrialized world. Only in Sweden, nearly 6000 women are diagnosed with breast cancer each year and 1/3 of them eventually succumb to the disease. Wnts are a family of genes that have been implicated in many human tumours, so far mainly studied in colorectal cancer where activated Wnt signalling occurs in a vast majority of tumours. Wh

The emittances of the electron beams at the MAX-laboratory accelerator system have been studied. Apart from the build-up of the diagnostic tools for precise determination of the beam spatial profiles, the objectives have been: a) to verify the accelerator design emittances at low currents and to try to determine the emittances also at high currents; b) to investigate possibilities to manipulate th

This study aims to: (1) identify some of the active and latent conditions that allow maritime security incidents to occur, and (2) explore the feasibility of adapting the Rasmussen-Svedung AcciMap as a tool for maritime security management. These twin objectives are pursued by applying concepts and principles, propounded by Rasmussen and Svedung, to a case study of the 1999 hijacking of the Alondr

A receiver front-end supporting contiguous and non-contiguous intra-band carrier aggregation scenarios with a fully integrated spectrum sensor that can detect both in-gap and out-of-band blockers has been implemented in 65nm CMOS technology. An NF of 2.5dB is achieved using a noise canceling LNTA, and linearized OTAs are used to achieve an IIP3 improvement of up to 6.5dB in-band and 11dB at the fi

Popular Abstract in Swedish I takt med att resultaten för behandling av cancer hos barn och ungdomar blivit bättre, har kraven på en god livskvalitet efter avslutad behandling ökat. Man beräknar att år 2005 kommer 1/700 unga vuxna mellan 25-35 års ålder att vara långtidsöverlevande efter barncancer. Mer än 2/3 av dem som behandlats kommer att ha någon form av sena biverkningar, och hos hälften av Evaluation of long-term side effects of treatment is important due to the growing number of childhood cancer survivors. How kidney function is affected over time needs to be clarified. In the first article, we investigated 247 healthy infants and children and established upper reference limits for several proteins in urine, to be used as markers for glomerular and tubular proteinuria in children w

Photon echoes have been studied both experimentally and theoretically, with the main part of the work centred around the concept of using photon echoes for all-optical data storage and processing. The four basic Boolean operators, AND, OR, NOT and XOR have been experimentally demonstrated using photon echoes. These constitute a complete set of Boolean operators. Selective erasure of digital data b

Kaposi's sarcoma-associated herpes virus (KSHV) encodes a complement inhibitor named KSHV complement control protein (KCP). We have previously shown that KCP inhibits the human complement system by disrupting the C3 convertase of complement. KCP can accelerate the decay of the classical C3 convertase and it can act as a cofactor for factor I (R), which then cleaves and inactivates C4b or C3b (in t

This chapter deals with the binding of the books in reconstructing the public library at Linköping after the fire that took place 1996. The book collections in the library were bound in different types of bindings depending on their function, frequency of use, type and year of print. This text describes how the requirements for several types of bindings were worked out and the binding process that

Laser-Rayleigh imaging has been employed to measure the relative fuel concentration in the gaseous jet region of DME sprays. The measurements were performed in an optically accessible diesel truck engine equipped with a common rail injection system. A one-hole nozzle was used to guarantee that the recorded pressure history was associated with the heat release in the imaged spray. To compensate for

Chiral building blocks are needed in the chemical and pharmaceutical industries for the production of fine chemicals and pharmaceuticals. The utilisation of microorganisms and enzymes to perform stereoselective reductions of carbonyl compounds is an efficient and widely applied method for the generation of chiral molecules. The aim of this thesis was to develop and improve yeast-catalysed bioredu