Riskfaktorer för Parkinsons sjukdom Parkinsons sjukdom är en kronisk, progressiv neurologisk sjukdom som drabbar över 1 % av personer över 65 år. Vid sjukdomen dör nervceller i hjärnan som producerar signalsubstansen dopamin. Dopamin behövs för att skicka signaler mellan hjärncellerna. På grund av bristen på dopamin får hjärnan svårare att kontrollera och styra nervsignaler som bland annat styr kBackground: Parkinson’s disease (PD) is a progressive neurodegenerative disease, affecting over 1% of individuals over the age of 60 years. Approximately 90% of the PD cases are idiopathic, where the etiology is multifactorial and caused by gene-environment interactions. Exposure to various environmental factors have seen to be strongly associated with an increased or decreased PD risk. We aimed t

Climate change and the Little Bustard: Breeding time is of the essence There is a lot of uncertainty concerning how climate change will affect species around the World. We are already observing some ecological changes, such as European butterflies moving their range northwards. However, to predict how species will be affected by climate change is “rocket science”. This study uses GPS coordinate

Can co-chaperone proteins help against Parkinson’s Disease ? Our cells have assigned proteins called ‘chaperone’ and their helper ‘co-chaperone proteins that work extensively to regulate and maintain the protein structure in our cells. However, proteins like α-synuclein manage to clump together in nerve cells and are believed to acquire toxic characteristics that contribute to the death and damag

This thesis aim to visualize and explore the methodological approach to finding the spatial patterning of crime through a geographical information system as a means for future guidance within spatial crime analysis. The analysis was applied to outdoor crimes for the city of Malmö in the year 2007. As a means for conducting this analysis a casestudy is performed. Both as a review of current police-

G protein-coupled receptor 30 (GPR30) is a ubiquitously expressed receptor reported to bind and become activated by estrogen (17β-estradiol). However, the role of GPR30 as an estrogen receptor for rapid estrogenic signaling is not completely accepted, and controversies exist regarding the identity of the cognate ligand, signaling, and subcellular localization of the receptor. Expression of GPR30 i

Syftet med den här studien är att hitta metoder för att kunna beskriva hur mätarlarver påverkar fjällbjörkskogen som ekosystem. I studien används olika metoder, fjärranalys och statistisk analys av satellitdata, samt intervjuer med personer som har god lokalkännedom. Genom att kombinera kvantitativ- och kvalitativmetod har dataanalysens slutsatser kunnat bekräftas. Det aktuella studieområdet liggeSince the mid-1950s, studies have frequently been conducted on couplings between geometrid moth outbreaks and mountain birch, though not nearly as much focus has been on connections between geometrid moth outbreaks and ground cover. Previous studies have shown that major outbreaks of Epirrita autumnata occur in 9 – 10-year cycles (Karlsson et al., 2004). Sometimes also the Operophtera brumata are

During the second half of August and the first part of September 2017, I radiotracked several European nightjars (Caprimulgus europaeus) around the Stensoffa area in Southern Sweden. Several locations were taken for each bird each night, including diurnal roost and nocturnal points composed by flying and resting behaviours. Being a long-distance migrator already on the way south during autumn migr

Optogenetics is unfolding new ways for us to study the nervous system and could one day be a standard approach to treat neurological diseases like epilepsy. To selectively study the effects on a subcellular level, microscopic light sources are needed. Nanostructure, light-emitting diodes (LEDs) can realize this criteria but processing to connect and protect them is necessary before any fruitful op

Fungi belonging to the genus Trichoderma are filamentous and soilborne, and are usually known for their plant growth-stimulating effects. Trichoderma viride is one of the species belonging to the genus, and is recognized as a plant symbiont known to improve plant growth and pathogen protection. Trichoderma species produce certain antifungal and antibiotic agents called peptaibols, as secondary met

The amazing Thermophile Rhodothermus marinus Thermophiles are microorganisms i.e. bacteria and archea that thrive between the temperature 41ºC to 122ºC. As they can grow at extremely high temperatures, they are also known as extremophiles. Mostly, they are found on geothermally heated places like hot springs or deep sea hydrothermal vents. Rhodothermus marinus is a thermophilic bacterium, inte

With protectionism on a global rise, non-tariff measures have been an object for public debates and research, as the work of WTO has reduced the possibilities of raising traditional trade restrictions as customs tariffs. Hence governments have turned to non-tariff measures and regulatory standards to fulfill their agendas. This study aims at shedding light on the question of whether non-tariff mea

Mitt arbete utgår från sagan ”Tomtebobarnen” av Elsa Beskow. Jag återupptäckte sagan som vuxen och kände en stark inspiration. Jag brukar inte ha en tydlig inspiration från ett annat medium kopplat till min gestaltning inom arkitektur, så detta var något som jag ville utforska. Inom arkitekturen är skapandeprocessen är en viktig del, därför tycker jag att det är intressant att undersöka den proces

Öresundsregionen är idag Nordens största transnationella samarbetsregion och omfattar hela Skånes län samt östra delen av Danmark. Sedan öppningen av Öresundsbron, år 2000, har regionen varit den arbetsmarknad som vuxit hastigast i Sverige och placerar sig betydligt högre upp än Stockholm på listan. Dock kan man inte se Öresundsregionen som en funktionellt integrerad enhet än. Ett närmare samarbetÖresund Region is, as of today, the biggest transnational region in Scandinavia. The inauguration of the Öresund Bridge in the year 2000 can be seen as the starting point of the regions rapid growth which has led to its surpassing of Stockholm in size. However, it has yet to fully function as an integral unit and a closer relationship between the economies is crucial for reaching a maximum of its

Recurrent Respiratory Papillomatosis: Studies of Immune Dysregulation Recurrent respiratory papillomatosis (RRP) is a disease caused by two specific low-risk types of human papillomavirus (HPV), HPV 6 and HPV 11. Benign tumors known as papillomas can grow in the respiratory tracts of patients afflicted with the disease. The papillomas growing in the respiratory tract can disrupt the vocal folds

A growing problem in many cities is that the traffic demand fluctuates heavily during the day and that it grows larger as the years go by. This calls for, and the technology to easier measure traffic enables, more efficient traffic light controls that can handle a greater traffic demand but also be adaptive. Centralised control of traffic light might, even though it can be both adaptive and effici

The established scientific reality of asbestos is that (a) asbestos is toxic at a minuscule dose, and (b) exposure should be avoided whenever possible, with the evidence expanding almost exponentially over the past century. The purpose of this research is to explore the historical and global socio-natural entanglements of the economy of asbestos and the resulting mechanisms at play to occlude and

När en ny bil skall designas är det viktigt att kunna förutse vissa fenomen innan en fysisk prototyp finns tillgänglig. Ljudet som orsakas av vägen är ett av dessa fenomen. På grund av känsligheten och komplexiteten i metoderna som används idag vore det intressant ifall man kan använda något enkelt mått för att få en känsla för detta fenomen i en tidig konceptutvecklingsfas. Frågan blir då, vilketThe noise, vibration and harshness (NVH) and body dynamic performance of automotive vehicles is highly dependent of the components included in the body structure and compartment, since they add mass, stiffness and damping to the overall structure. Today, the noise levels in the compartment are predicted using complex and detailed computational models during both early and late stages of the vehicl

Today, the car industry has become one of the greatest users of both wireless and cellular technologies and is increasingly dependent especially in the area of wireless communication. Communication among vehicles is offering a lot of benefits and has testified improvement on safety, efficiency and possible automation of the traffic. A lot of research has been focused on measurement campaigns, by i

This thesis describes the method of identifying unknown parameters that affect the dynamics of a given quadcopter, also known as grey box system identification. This was primarily done utilising an inertial measurement unit and a motion capture camera system. A system of equations describes the dynamics of the quadcopter, and was later coupled with data gathered while flying, in order to use diffe

In this thesis the heating area of a belt furnace for annealing metal powder has been modeled. The model was extended with PI-controllers for controlling the energy added to the model. It was simulated with differently tuned controllers to test tuning principles for finding suitable control parameters for the process. The most promising tuning principles was then written as a manual with the aim f