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Dendrokronologisk analys av Marka kyrka i Falköping
Dendrokronologisk analys av Hörsne kyrka, Gotland
Vedanatomisk analys för C14analys av tre brunnar i Härslöv, Skåne
Dendrokronologisk analys av Åre kyrka, loge i Bodsjö socken och loge i Rödöns socken
Deep label fusion : A generalizable hybrid multi-atlas and deep convolutional neural network for medical image segmentation
Deep convolutional neural networks (DCNN) achieve very high accuracy in segmenting various anatomical structures in medical images but often suffer from relatively poor generalizability. Multi-atlas segmentation (MAS), while less accurate than DCNN in many applications, tends to generalize well to unseen datasets with different characteristics from the training dataset. Several groups have attempt
Clinical impact of influenza vaccination after ST- and non-ST-segment elevation myocardial infarction - insights from the IAMI trial
Background: Influenza vaccination early after myocardial infarction (MI) improves prognosis but vaccine effectiveness may differ dependent on type of MI. Methods: A total of 2,571 participants were prospectively enrolled in the Influenza vaccination after myocardial infarction (IAMI) trial and randomly assigned to receive in-hospital inactivated influenza vaccine or saline placebo. The trial was c
Identification of Distinct Soluble States During Fibril Formation Using Multilinear Analysis of NMR Diffusion Data
Protein misfolding and self-assembling into amyloid structures are associated with a number of diseases. Characterization of protein amyloid formation reactions is a challenging task as transient populations of multiple species are involved. Here we outline a method for identification and characterization of the individual soluble states during protein amyloid formation. The method combines NMR tr
Routine revascularization with percutaneous coronary intervention in patients with coronary artery disease undergoing transcatheter aortic valve implantation – the third nordic aortic valve intervention trial – NOTION-3
Background: Coronary artery disease (CAD) frequently coexists with severe aortic valve stenosis (AS) in patients planned for transcatheter aortic valve implantation (TAVI). How to manage CAD in this patient population is still an unresolved question. In particular, it is still not known whether fractional flow reserve (FFR) guided revascularization with percutaneous coronary intervention (PCI) is
Tree species traits and mycorrhizal association shape soil microbial communities via litter quality and species mediated soil properties
Soils harbor a vast diversity of soil microbiota, which play a crucial role in key ecosystem processes such as litter transformation and mineralization, but how complex plant-soil interactions shape the diversity and composition of soil microbiota remains elusive. We performed amplicon sequencing of DNA isolated from mineral topsoil of six common European trees planted in multi-site common garden
Book review : Drechsler, Stefan. Illuminated Manuscript Production in Medieval Iceland – Literary and Monastic Activities of the Helgafell in the Fourteenth Century
Understanding quality data correctly : a randomized comparison of presentation formats among cancer patients and relatives
Background: Patient representatives are increasingly engaged in quality in health care, and even though quality data are publicly available, correct interpretation may be challenging. We designed a randomized study with the primary aim to examine the association between preferred data presentation format and the interpretation of quality data among cancer patients and relatives. Material and metho
The effect of weathering on the surface moisture conditions of Norway spruce under outdoor exposure
Understanding wood surface moisture variations is fundamental to the modelling of moisture content. Exposure to sunlight, fluctuating temperature and rain leads to superficial deterioration and reduced surface hydrophobicity. Here, the effect of weathering was studied through monitoring the surface and global moisture content of axially matched pre-weathered and planed sets of specimens exposed ou
Bilirubin Levels in Neonates ≥ 35 Weeks of Gestation Receiving Delayed Cord Clamping for an Extended Time - an Observational Study
OBJECTIVE: To describe bilirubin levels in neonates ≥ 35+0 gestational weeks, receiving delayed cord clamping (CC), in relation to the updated Bhutani nomogram.STUDY DESIGN: This was a retrospective, observational study based on data from medical records and local data sheets. Singleton neonates, born vaginally at a gestational age (GA) ≥ 35+0, and with a registered time to CC and at least one reg
Proof-of-concept method to study uncharacterized methyltransferases using PRDM15
The PRDM family of methyltransferases has been implicated in cellular proliferation and differentiation and is deregulated in human diseases, most notably in cancer. PRDMs are related to the SET domain family of methyltransferases; however, from the 19 PRDMs only a few PRDMs with defined enzymatic activities are known. PRDM15 is an uncharacterized transcriptional regulator, with significant struct
Triglyceride-glucose (TyG) index is a predictor of arterial stiffness, incidence of diabetes, cardiovascular disease, and all-cause and cardiovascular mortality: A longitudinal two-cohort analysis
BACKGROUND: Triglyceride-glucose (TyG) index is a useful low-cost marker of insulin resistance. We aimed to evaluate the association between TyG index and arterial stiffness, incidence of diabetes, adverse cardiovascular outcomes, and all-cause and cardiovascular mortality in two large prospective Swedish cohorts, the Malmö Diet and Cancer Study-Cardiovascular Cohort (MDCS-CV) and the Malmö Preven
On injustices raised by the implementation of low-carbon technologies
Conceptualizing social resilience in the context of migrants’ lived experiences
The current concept of social resilience, which developed from the classic definition of resilience, neglects social resilience as a social phenomenon including social experiences and practices in the face of change and adversity. I argue that framing social resilience as a capacity or ability undermines its characteristics as a complex and contextualized social phenomenon that contributes to adap
Sudden cardiac death in synucleinopathies
The purpose of this study was to investigate the cause of death in subjects with α-synucleinopathies (ASs) and the confirmed presence of cardiac α-synuclein (α-syn), compared to non-AS disorders in a neuropathologically confirmed cohort. In total, 78 neuropathologically confirmed AS cases positive for cardiac α-syn were included in the study. Individuals with other neurocognitive diseases, having
Quantification of structures in freeze-dried materials using X-ray microtomography
The structure of a freeze-dried material is essential for its ability to preserve and protect biologics such as proteins, cells and other sensitive structures. The structure of a typical freeze-dried matrix can be described as pores surrounded by thin walls where the walls are the encapsulating material (for e.g. cells). The objective of this investigation is to evaluate X-ray microtomography (µCT