Using rolling circle amplification (RCA) and two different ways of signal readout, we developed analytical methods to detect the receptor-binding domain (RBD) of SARS-CoV-2 spike protein (S protein). We modified streptavidin-coated magnetic beads with an aptamer of RBD through a biotin-tagged complementary DNA strand (biotin-cDNA). Binding of RBD caused the aptamer to dissociate from the biotin-cD

Although photothermal therapy is of significance in therapeutic strategies for fighting bacterial infection, the precise target of photothermal agents to bacterial sites is still a challenge. In this work, lipopolysaccharide (LPS) imprinted photothermal molecularly imprinted polymers (PMIP) were prepared for the efficient capture and elimination of Pseudomonas aeruginosa. The LPS derived from Pseu

We identify biomarkers for disease progression in three type 2 diabetes cohorts encompassing 2,973 individuals across three molecular classes, metabolites, lipids and proteins. Homocitrulline, isoleucine and 2-aminoadipic acid, eight triacylglycerol species, and lowered sphingomyelin 42:2;2 levels are predictive of faster progression towards insulin requirement. Of ~1,300 proteins examined in two

Syncope, a form of transient loss of consciousness, remains a complex medical condition for which adverse cardiovascular outcomes, including death, are of major concern but rarely occur. Current risk stratification algorithms have not completely delineated which patients benefit from hospitalization and specific interventions. Patients are often admitted unnecessarily and at high cost. Artificial

The beamlines at CERN's North and East Areas offer secondary beams in a wide range of momenta between 0.5 GeV/c and 400 GeV/c for fixed-target experiments as well as for test beam campaigns with a flexible configuration and variable beam composition and intensities. Recently, two new facilities for neutrino detectors tests have been established in an extension of the CERN North Area in context of

Particle identification with threshold Cherenkov detectors, using a moderately pressurized radiating gas with an adequate refractive index, is one of the most common techniques employed in high-energy physics. However, available gases with relatively high refractive indices, that simultaneously preserve their gaseous phase at room temperature and moderate pressures, are rare. Until recently, R-12

The recently constructed H4-VLE beam line, a tertiary extension branch of the existing H4 beam line in the CERN North Area, was commissioned in October 2018. The beam line was designed with the purpose of providing very low energy (VLE) hadrons and positrons to the NP-04 experiment, in the momentum range of 1-7 GeV/c. The production of these low-energy particles is achieved with a mixed hadron (pi

For many decades the CERN North Area facility at the Super Proton Synchrotron (SPS) has delivered secondary beams to various fixed target experiments and test beams. In 2018, two new tertiary extensions of the existing beam lines, designated "H2-VLE" and "H4-VLE", have been constructed and successfully commissioned. These beam lines have been designed to provide charged particles of both polaritie

Background: To support a victim of violence and establish the correct penalty for the perpetrator, it is crucial to correctly evaluate and communicate the severity of the violence. Recent data have shown these communications to be biased. However, computational language models provide opportunities for automated evaluation of the severity to mitigate the biases. Objective: We investigated whether

Syftet med denna sammanläggningsavhandling är att belysa de etiska, juridiska och politiska konsekvenserna av olika försök att hantera lidande hos djur orsakat av industriell djurproduktion. På basis av kvalitativa studier utförda i Danmark undersöker avhandlingen hur skötseln av lantbruksdjur förhandlas inom olika sociala domäner. För detta ändamål använder avhandlingen rättssociologiska och tvärThis compilation thesis aims to develop an understanding of the ethical, legal and political implications associated with different strategies to address the suffering of animals caused by industrialised agriculture. Based on qualitative analysis conducted in Denmark, the research explores how ethical commitment to the situation of farmed animals is negotiated across different domains. The thesis

This brief anthology presents the basics of the interdisciplinary course called Smart City Governance – AI Ethics in a Spatial Context, given at LTH, Lund University. Furthermore, it includes three selected essays from the main assignment written by students from the class of 2022/2023. These provide with examples of the topics possible to analyse when combining engineering students from programme

In state formation research, princely houses have been a blind spot. The development of states has been discussed from many perspectives, like interstate competition, internal social conflicts, fiscal-military developments, etc., but at the centre of most European states, there was a princely house. These ruling houses have been overlooked in studies about state formation. What’s more, when discus

The introduction discusses the concepts of dynasty and state formation and their interrelated nature. It stresses the need to def ine the concept of dynasty as a kinship group with an acute sense of historical continuity, claiming the right to rule a certain territory and manifesting this claim in political, social and cultural ways; and the related concept of dynasty formation as the acts, consci

Princely marriages are here seen as a key component in dynasty formation and dynasty securing. The marriages of the Danish royal house and three houses of the Empire are studied for the period c. 1530–1700. Most of them took place within what can be labelled a Scandinavian-German-Lutheran marriage sphere. It was a highly hierarchized sphere with little contact between top (royal and electoral hous

Complementary pathways have been offered as a possible solution for facilitating legal admission of people in need of international protection. The current debates about these pathways are characterised by a conceptual and legal quagmire since various issues are invoked and conflated. The objective of this article is to dissect the relevant issues in light of the existing relevant legal frameworks

Editorial to a special issue