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Serum proteome profiling of pancreatitis using recombinant antibody microarrays reveals disease-associated biomarker signatures

PURPOSE: Pancreatitis is an inflammatory state of the pancreas, for which high-performing serological biomarkers are lacking. The aim of the present study was to evaluate the use of affinity proteomics for identifying potential markers of disease and stratifying pancreatitis subtypes. EXPERIMENTAL DESIGN: High-content, recombinant antibody microarrays were applied for serum protein expression prof

Lactobacillus plantarum 299v Does Not Reduce Enteric Bacteria or Bacterial Translocation in Patients Undergoing Colon Resection.

BACKGROUND: Probiotics may exert beneficial effects in the gastrointestinal tract. This randomized trial investigated the effect of the probiotic Lactobacillus plantarum 299v on the intestinal load of potentially pathogenic bacteria, bacterial translocation, and cell proliferation in elective colon surgery. METHODS: Seventy-five patients were randomized to pre- and postoperative oral intake of L

Acute mastoiditis in children aged 0-16 years-A national study of 678 cases in Sweden comparing different age groups.

OBJECTIVE: To compare the characteristics of acute mastoiditis in children in different age groups in order to identify risk groups and risk factors for acute mastoiditis. METHODS: Records for all children aged 0-16 years treated for acute mastoiditis during 1993-2007 at 33 Ear, Nose and Throat departments in Sweden were reviewed retrospectively according to defined criteria for acute mastoidi

Phase of the Atomic Polarization In High-order Harmonic-generation

A recently formulated theory of high-order harmonic generation by low-frequency laser fields [Anne L'Huillier et al., Phys. Rev. A 48, R3433 (1993)] allows us to study the phase of the induced atomic dipole moment. We show that this phase exhibits a piecewise-linear dependence on the laser intensity. This dependence can be interpreted in quasiclassical terms, and is related to the action acquired

Reproductive and oncologic outcome following robot-assisted laparoscopic radical trachelectomy for early stage cervical cancer.

Objective To investigate the reproductive and oncologic outcome following robotic radical trachelectomy for early stage cervical cancer. Methods All women with early stage cervical cancer planned for fertility-sparing robotic trachelectomy between December 2007 and April 2015 at two tertiary referral centers in Sweden were identified. Perioperative- and follow-up data was retrieved from prospectiv

P-selectin mediates neutrophil rolling and recruitment in acute pancreatitis.

BACKGROUND: The adhesive mechanisms regulating leucocyte-endothelium interactions in the pancreas remain elusive, but selectins may play a role. This study examined the molecular mechanisms mediating leucocyte rolling along the endothelium in the pancreas and the therapeutic potential of targeting the rolling adhesive interaction in acute pancreatitis (AP). METHODS: Pancreatitis was induced by ret

Modern haemophilia care.

Haemophilia care has undergone substantial improvements during the past 40-50 years. Early clotting factor concentrates were not sufficiently refined to enable self-administered treatment at home until the 1970s. Unfortunately, these advances led to transmission of viral diseases including HIV and hepatitis, resulting in an increased burden of morbidity and mortality, especially during the 1980s.

Correlation of longitudinal cerebrospinal fluid biomarkers with cognitive decline in healthy older adults.

BACKGROUND: Abnormal cerebrospinal fluid (CSF) biomarker levels predict development of Alzheimer disease with good accuracy and are thought to precede cognitive deterioration. OBJECTIVE: To investigate whether changes in CSF biomarker levels over time in healthy older adults are associated with a concurrent decline in cognitive performance. DESIGN: Retrospective analysis of longitudinal CSF biomar

Three methods for optimizing single-shortest path routing

Intra-domain routing in IP networks is based on the shortest path principle by assigning administrative weights (costs) to links. The resulting least-cost paths determine routes between pairs of routers. If several such equal-cost paths exist between a pair of routers, it may not be clear which of them is actually used to route traffic. This makes it difficult to predict the network traffic flow d

Supporting presence in collaborative environments by haptic force feedback

An experimental study of interaction in a collaborative desktop virtual environment is described. The aim of the experiment was to investigate if added haptic force feedback in such an environment affects perceived virtual presence, perceived social presence, perceived task performance, and task performance. A between-group design was employed, where seven pairs of subjects used an interface with

Fracture characterization at Valhall: Application of P-wave amplitude variation with offset and azimuth (AVOA) analysis to a 3D ocean-bottom data set

The delineation and characterization of fracturing is important in the successful exploitation of many hydrocarbon reservoirs. Such fracturing often occurs in preferentially aligned sets; if the fractures are of subseismic scale, this may result in seismic anisotropy. Thus, measurements of anisotropy from seismic data may be used to delineate fracture patterns and investigate their properties. Her

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Abstract in German Die Lektüre von Still Songs eröffnet einen neuen, interessanten und zugleich kritischen Blick auf Celans „MusikGedichte“ und deren Vertonungen und auf die Celan-Forschung überhaupt. Passagen zur Detailebene einzelner Gedichte – wie Todesfuge, Schlaflied, Saitenspiel, Engführung oder Fadensonnen – und deren Vertonungen – durch Tilo Medek, Erhard Karkoschka, Harrison Birtwistle, A