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MODELING OF PROSTATE-SPECIFIC ANTIGEN AND HUMAN GLANDULAR KALLIKREIN STRUCTURES

The three dimensional structures of human prostate specific antigen (PSA) and glandular kallikrein (hGK) were modeled based on porcine pancreatic kallikrein A. High sequence similarity and conserved framework of serine proteases enabled accurate modeling. The catalytic site region consisting of catalytic triad, residues forming oxyanion hole and main-chain substrate binding residues were conserved

Numerical investigations of the laminating effect in laminated beams

The paper presents numerical results concerning the so-called laminating effect of laminatedbeams. Using the finite-element method, it is shown that the assumption often made of a stress redistribution taking place around weak zones is not necessarily true. A fracture mechanics approach to a possible explanation for the laminating effect is also presented. Here a nonlinear fracture mechanics model

Guds rike

En översikt över gudsrikestanken i Bibeln samt över diskussioner som förts angående gudsrikestanken från Immanuel Kant fram till nutiden

Experimental transition probabilities and improved level energies in YbIII

Radiative lifetimes of nine out of the twelve 4f(13)6p levels in Yb III have been measured, seven of these for the first time. A Penning discharge lamp is introduced as a continuous plasma source, in which the lifetimes are determined with the time-resolved laser-induced fluorescence technique by pumping from metastable 5d and 6s levels. Spectra of the same source are recorded with a Fourier-trans

Investigations of the Influence of Mixture Preparation on Cyclic Variations in a SI-Engine, Using Laser Induced Fluorescence

To study the effect of different injection timings on the charge inhomogeneity, planar laser-induced fluorescence (PLIF) was applied to an operating engine. Quantitative images of the fuel distribution within the engine were obtained. Since the fuel used, iso-octane, does not fluoresce, a dopant was required. Three pentanone was found to have vapor pressure characteristics similar to those of iso-

Association between IgM against an aldehyde-modified peptide in apolipoprotein B-100 and progression of carotid disease

Background and Purpose - Autoantibodies against antigens in oxidized low-density lipoprotein are common in people; experimental studies suggest that these immune responses have a functional role in the disease process. The aim of this study was to evaluate the relationship between the immune response against one defined oxidized low-density lipoprotein antigen, the aldehyde-modified peptide corres

Green approach for the preparation of biodegradable lubricant base stock from epoxidized vegetable oil

A novel process for the production of biodegradable lubricant-based stocks from epoxidized vegetable oil with a lower pour point via cationic ion-exchange resins as catalysts was developed. This involves two steps, first, ring-opening reactions by alcoholysis followed by esterification of the resultant hydroxy group in the first step. The ring-opening reaction of epoxidized soybean oil with differ

Prevention of autoimmunity by targeting a distinct, noninvariant CD1d-reactive T cell population reactive to sulfatide

Class I and class II MHC-restricted T cells specific for proteins present in myelin have been shown to be involved in autoimmunity in the central nervous system (CNS). It is not yet known whether CD1d-restricted T cells reactive to myelin-derived lipids are present in the CNS and might be targeted to influence the course of autoimmune demyelination. Using specific glycohpid-CD1d tetramers and clon

Jämställdhetsrevolutionen finns i lagstiftningen

This article discusses Swedish gender equality policy and excellent gender equality laws. The problem is not a lack of policy documents and laws, the problem is turning this law system in to practise.

Genetic and Environmental Influences on Mothering of Adolescents: A Comparison of Two Samples

This study examined 2 samples of adolescents and mothers using a child-based design (Nonshared Environment in Adolescent Development [NEAD] project, N = 395 families) and a parent-based design (Twin Moms [TM] project, N = 236 twin family pairs) to compare genetic and environmental influences on mothering. For both samples, the same measures of positivity, negativity, control, and monitoring were u

Book and Library History

A short sketch of the concept of Book and Library History as a field of study, according to the author, holder of the Chair in that subject at Lund University.