BACKGROUND: Clonal hematopoiesis of indeterminate potential (CHIP), a common age-associated phenomenon, associates with increased risk of both hematological malignancy and cardiovascular disease. Although CHIP is known to increase the risk of myocardial infarction and heart failure, the influence of CHIP in cardiac arrhythmias, such as atrial fibrillation (AF), is less explored. METHODS: CHIP prev

Objective: To screen a general pediatric population for type 1 diabetes (T1D), celiac disease (CD), and autoimmune thyroid disease (AITD) after home capillary sampling. Methods: Swedish schoolchildren between 6–9 years and 13–16 years of age were invited to screening by taking a capillary sample at home. Samples were returned by mail and assessed for autoantibodies associated with T1D, CD, and AIT

Motivated by the analysis of the tunneling effect for the magnetic Laplacian, we introduce an abstract framework for the spectral reduction of a self-adjoint operator to a hermitian matrix. We illustrate this framework by three applications, firstly the electro-magnetic Laplacian with constant magnetic field and three equidistant potential wells, secondly a pure constant magnetic field and Neumann

The ever evolving automotive industry is pushing for further electrification of the vehicle fleet and the need for new electric drivetrains is therefore in high demand. The Formula Student competitions have also shifted their focus towards electric vehicles where innovative and efficient drivetrains are premiered in the design events. This master thesis work aimed to continue the development of Lu

Den nya högerledda regeringen i Finland under Petteri Orpo är i full färd med att göra genomgripande förändringar av den finska arbetsmarknadsmodellen. Det handlar om konflikträtten, lönebildningen, förhandlingssystemet och de sociala förmånerna:•Begränsad rätt till sympatiåtgärder och politiska strejker samt kraftigt ökade böter i samband med olagliga konfliktåtgärder•Statliga medlare får inte go

Background and purpose: Tamoxifen remains an important adjuvant treatment in premenopausal patients with hormone receptor-positive breast cancer. Thus, determination of hormone receptors is important. Here, we compare cytosol-based methods, immunohistochemistry (IHC), and gene expression (GEX) analysis for determining hormone receptor status in premenopausal breast cancer patients from a randomise

Flowering time is an important phenological trait in plants and a critical determinant of the success of pollination and fruit or seed development, with immense significance for agriculture as it directly affects crop yield and overall food production. Shifts in the growth season, changes in the growth season duration and changes in the production rate are environmental processes (potentially link

The relationship between remote work and employee well-being represents a longstanding debate in the management literature, and it has been rekindled by the remote work adoption forced by COVID-19 lockdowns. Previous literature has shown that remote working can enhance flexibility and work–life balance under certain conditions. However, it can also be a source of increased stress, burnout, and gre

Magnetic one-dimensional structures are attractive nanomaterials due to the variety of potential applications they can provide. The fabrication of bimetallic 1D structures further expands the capabilities of such structures by tailoring the magnetic properties. Here, a single-step template-free method is presented for the fabrication of 1D FeCo alloy nanochains. In this approach, charged single-cr

Continuous superporous agarose beds constitute a new support material for chromatography, biocatalysis and electrophoresis. The bed consists of a single piece of agarose gel, homogeneously transected by flow-carrying pores, which easily can be varied in the range of 10–100 μm. In this work, large diameter beds (60 mm) were prepared and used in specially designed radial flow columns. The basic chro

Conservation biological control in agricultural landscapes aims to promote natural enemy populations to mitigate short and long-term pest damage on crops. However, natural enemy populations in agricultural landscapes typically rely on crop pests and non-pest prey populations resulting in complex trait- dependent ecological interactions. Such communities, of pests, non-pest prey, and natural enemie

Deep-learning methods using unpaired datasets hold great potential for image reconstruction, especially in biomedical imaging where obtaining paired datasets is often difficult due to practical concerns. A recent study by Lee et al. (Nature Machine Intelligence 2023) has introduced a parameterized physical model (referred to as FMGAN) using the unpaired approach for adaptive holographic imaging, w

The X-ray flux provided by X-ray free-electron lasers and storage rings offers new spatiotemporal possibilities to study in-situ and operando dynamics, even using single pulses of such facilities. X-ray Multi-Projection Imaging (XMPI) is a novel technique that enables volumetric information using single pulses of such facilities and avoids centrifugal forces induced by state-of-the-art time-resolv

In EU migration law scholarship, accounts of crisis and its relation to law flourished in relation to the migrant and refugee arrivals which took place in the in the period of 2015-2016. To offer new insight on the relation of crisis, EU law-making and migration, this chapter focuses on the same topic but from an entirely different angle and time frame. Specifically, this chapter does not look at

From 2015 to 2016 onwards, migration has been subjected to intense political contestation within EU Member States. In this context, sustainable migration has become the new overarching objective of the Commission. Despite the various references to sustainable migration, a closer investigation of EU migration law and policy does not provide a coherent picture of the legal implications of this conce

Syftet med följande studie var att analysera framställningen av Återställ Våtmarker under 2023 i fyra svenska nyhetskanaler; Aftonbladet, Dagens Nyheter (DN), Sveriges Radio (SR) och Sveriges Television (SVT). Totalt har 112 artiklar analyserats. I studien förs en diskussion kring vad framställningen av organisationen haft för effekter på konsumenterna av nyheterna. Fallstudien är en kvalitativ inThis study analyses four Swedish news channels’ depiction of the protest group Återställ Våtmarker (EN: Restore Wetlands) during the course of the year 2023. The analysed outlets are Aftonbladet, Dagens Nyheter (DN), Sveriges Radio (SR) and Sveriges Television (SVT). In total, a number of 112 articles have been analysed. The study discusses what effect the depiction of Återställ Våtmarker has had

This chapter begins by explaining that family rights have been protected under EU law long before the adoption of the Charter. In particular, the chapter argues that the Court of Justice of the EU consolidated the protection of family life through a free movement rationale, guided by the need to eliminate obstacles to the exercise of the fundamental freedoms guaranteed by the Treaty. The chapter t

Background: Advancements in immunotherapeutic approaches only had a modest impact on the therapy of lung neuroendocrine neoplasms (LNENs). Our multicenter study aimed to investigate the expression patterns of novel immunotherapy targets in intermediate- and high-grade LNENs. Methods: The expressions of V-domain Ig suppressor of T cell activation (VISTA), OX40L, Glucocorticoid-induced TNF receptor