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Characterization of atrial fibrillation using the surface ECG: time-dependent spectral properties

Time-frequency analysis is considered for characterizing atrial fibrillation in the surface electrocardiogram (ECG). Variations in fundamental frequency of the fibrillatory waves are tracked by using different time-frequency distributions which are appropriate to short- and long-term variations. The cross Wigner-Ville distribution is found to be particularly useful for short-term analysis due to i

Determination of wound strength for quantitation of skin damage after pressure ischemia. An experimental study in rabbits

Rabbits skin folds were placed in plexiglass chambers enabling control of the skin fold temperature during cuff compression (200 mmHg) for 4 hours. In 10 animals the skin folds were kept at 36 degrees C - in another 10 animals the skin fold temperature was lowered to 10 degrees C. To quantitate the skin injury caused by the pressure ischemia a standardized wound was made, and immediately closed, a

Discrete Methods used in Graph Theory and Linear Programming

The content of the thesis is divided into two parts; graph theory and linear programming. The main results in the first part concerns extremal graph theory. Here we want to determine the number of edges in a graph needed to ensure the existence of certain local structures. Upper and lower bounds are given for the number of edges in a graph to ensure triangles and quadrilaterals respectively, when

Conceptual spaces as a framework for knowledge representation

The dominating models of information processes have been based on symbolic representations of information and knowledge. During the last decades, a varietyof non-symbolic models have been proposed as superior. The prime examples of models within the non-symbolic approach are neural networks. However, to a large extent theylac k a higher-level theoryof representation. In this paper, conceptual spac

Reducing arrhythmogenic effects in the isolated heart enriching roentgen contrast media with electrolytes. Survey and present state

A review of the literature on the effects of adding electrolytes to ionic as well as nonionic contrast media (CM) in the isolated heart model reveals that both ionic and nonionic CM favor from such addtion, if the added electrolytes are balanced with respect to each other. By enriching nonionic monomeric as well as dimeric CM with such a balanced electrolyte solution, the risk of ventricular fibri

Changes in carbohydrate and glucosinolate composition in white cabbage (Brassica oleracea var. capitata) during blanching and treatment with acetic acid

The effect of blanching and treatment with white vinegar containing acetic acid on dietary fibre, low-molecular-weight carbohydrates and glucosinolates was studied in two cultivars of white cabbage (Heckla and Predikant). The total content of dietary fibre and low-molecular-weight carbohydrates was similar in both cultivars (24 and 60 g/100 g DM, respectively), while the distribution between solub

SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells.

Measurements of membrane capacitance were applied to dissect the cellular mechanisms underlying PKA-dependent and -independent stimulation of insulin secretion by cyclic AMP. Whereas the PKA-independent (Rp-cAMPS–insensitive) component correlated with a rapid increase in membrane capacitance of ~80 fF that plateaued within ~200 ms, the PKA-dependent component became prominent during depolarization

Byarnas bönder - de historiska källorna

Rapporten är ett supplement till Riksantikvarieämbetets bokprojekt "Skånska spår - arkeologi längs Västkustbanan". Det äldre historiska källmaterialet för fem medeltida byar (Glumslöv, Häljarp, Rya, Säby och Särslöv) presenteras och analyseras, främst med avseende på bebyggelse- och ägostruktur.

Fire Safety Analysis of a Health Care Facility

A methodology for deriving individual risk to people in a health care facility due to fire, is presented. The risk is expressed by the First Order Second Moment reliability index b. The evacuation time for the patients is compared to the time to untenable conditions arise. Subjecting variables to uncertainty results in a reliability index value for the escape time margin. The influence on reliabil

Luminescence quenching by inter-chain aggregates in substituted polythiophenes

Time-resolved photo luminescence spectra measured in solid films of two polythiophene derivatives with different chain packing allow to distinguish emission of intra-chain excitations from the luminescence of inter-chain aggregates. Aggregate luminescence is red shifted by about 0.1 eV relative to intra-chain emission and shows vibronic coupling to the C=C bond stretch with the Huang-Phys factor o

Registration of emission and transmission whole-body scintillation-camera images

In this work, a method for registration of whole-body (WB) scintillation-camera images is presented. The primary motive for the development is to perform activity quantification using the conjugate view method on an image basis. Accurate image registration is required for sequential anterior and posterior scans, for serial emission images for analysis of the biokinetics, and for transmission and e

Acute leukemias of ambiguous origin

Objectives: This session of the Society for Hematopathology/ European Association for Haematopathology Workshop focused on acute leukemias of ambiguous origin. Methods: We provide an overview of mixed-phenotype acute leukemia (MPAL) as recognized in the current World Health Organization classification and summarize diagnostic criteria for major categories of MPAL: B/myeloid, T/myeloid, B/T, and B/

Is There a Role for Flow Cytometry in the Evaluation of Patients With Myelodysplastic Syndromes?

This review focuses on the most recent literature concerning flow cytometry (FCM) application for diagnosis of myelodysplastic syndrome (MDS). Aberrant FCM results have been defined as abnormalities in at least three tested features comprising at least two bone marrow (BM) cell compartments. FCM results should be interpreted together with the BM smear cytology, the morphological assessment of BM b

Screening bone marrow samples for abnormal lymphoid populations and myelodysplasia-related features with one 10-color 14-antibody screening tube

Background We have designed one-tube 14-antibody 10-color flow cytometry (FCM) panel that would provide maximum information on lymphoid and myeloid cell subsets in bone marrow aspirates (BMA) from patients with cytopenia(s). Samples and Methods BMA from 8 normal donors, from 286 non-malignant hospital controls, 92 myelodysplastic syndromes (MDS), 47 myeloproliferative neoplasms (MPN), and from 14

Flow cytometry immunophenotyping in integrated diagnostics of patients with newly diagnosed cytopenia : One tube 10-color 14-antibody screening panel and 3-tube extensive panel for detection of MDS-related features

Acute leukemia, myelodysplastic syndromes (MDS), myeloproliferative neoplasms and lymphomas are the most prevalent diagnoses in adults presenting with new onset cytopenia. Here, we describe two 10-color panels of surface markers (screening and comprehensive panel) applied at the Flow Cytometry Laboratory, University Health Network, Toronto, ON, Canada. A 10-color flow cytometry is applied using th

Detection of central nervous system involvement in childhood acute lymphoblastic leukemia by cytomorphology and flow cytometry of the cerebrospinal fluid

Background: Therapy directed at the central nervous system (CNS) is an essential part of the treatment for childhood acute lymphoblastic leukemia (ALL). The current evaluation of CNS involvement based on cytomorphological examination of the cerebrospinal fluid (CSF) alone is not as sensitive with low cell counts as flow cytometric immunophenotyping (FCI) of the CSF. However, the importance of low

The role of diagnostic tissue in research

There are two broad classes (or categories) of excised human tissue: diagnostic tissue (DT) and research tissue (RT). Classification of excised human tissue does not define its ultimate use and ultimate use of excised human tissue does not define its classification. While both DT and RT can be used for research, DT has specific requirements with respect to how it must be handled if and when being

Dendritic Cells in Bone Marrow at Diagnosis and after Chemotherapy in Adult Patients with Acute Myeloid Leukaemia

Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenitor cells. Two subsets, plasmacytoid DCs (pDCs) and myeloid DCs (mDCs), have been identified. Little is known regarding DC levels in bone marrow of patients with acute myeloid leukaemia (AML) before and after chemotherapy. We investigated relative pDC and mDC levels in bone marrow from 37 hospital controls and 60 patients