In this report we demonstrate an increase in the steady-state level of bone sialoprotein (BSP) mRNA in rat calvaria and a rat osteosarcoma cell line (ROS 17/2.8) after treatment with the synthetic glucocorticoid, dexamethasone. In contrast, 1.25-dihydroxyvitamin D3 reduced the amount of BSP mRNA in calvaria and inhibited the dexamethasone induction in ROS 17/2.8 cells. The increase in BSP mRNA is

The pseudo-Thellier technique was applied to recover relative palaeointensity (PT-RPI) estimates from four piston cores retrieved from a Holocene lake sediment sequence in the province of Smaland, central southern Sweden. A time-depth model between 11,000 and 450 cal BP was based on a combination of calibrated radiocarbon ages and the ages of established palaeomagnetic secular variation (PSV) feat

Organic farming has been suggested to counteract declines in farmland biodiversity, but comparisons to conventional farming have produced variable outcomes. To examine whether this is due to the landscape context farms are situated in and traits of the studied organisms, we surveyed bumble bees in cereal field borders and margins at 12 pairs of matched organic and conventional farms, with half the

Sometimes instances of perceived causation turn out to lack causal relata. The reasons may vary. Causation may display itself as prevention, or as omission, and in some cases causation occurs within such complex environments that few of the things we associate with causes and effects are true of them, etc. But even then, there may be causal explanations to be had. This suggests that the explanator

There is growing evidence that immune functions are linked to the regulation of body fat. Our studies of knockout mice indicate that both endogenous interleukin (IL)-6 and IL-1 can suppress mature-onset obesity. We now investigated whether four common polymorphisms of the IL6 and IL1 systems are associated with the fat mass measured with dual-energy X-ray absorptiometry (DXA) in elderly men (n = 3

The interaction between composite colloidal particles composed of a spherical core and grafted AB-diblock polyampholytes (diblock copolymers with oppositely charged blocks) are investigated by using a coarse-grained model solved with Monte Carlo simulations. The B block is end-grafted onto the core of the colloid and its linear charge density is varied, whereas the linear charge density of the A b

We compute Poisson kernels for integer weight parameter standard weighted biharmonic operators in the unit disc with Dirichlet boundary conditions. The computations performed extend the supply of explicit examples of such kernels and suggest similar formulas for these Poisson kernels to hold true in more generality. Computations have been carried out using the open source computer algebra package

Conidia of Penicillium chrysogenum and Penicillium frequentans and sporangiospores of Rhizopus rhizopodiformis, Rhizomucor pusillus, and Mucor racemosus were subjected to partition in aqueous polymer two-phase systems. The partition behavior differed drastically between the conidia of the two Penicillium species and the sporangiospores of the three species of phycomycetes. This difference in parti

Transfer of embryos at the blastocyst stage has been associated with exceptionally high implantation rates. There are, however, only a few prospective randomized studies comparing day 3 versus day 5 embryo transfer. Furthermore, the number of embryos replaced in the day 3 group transfer is often higher than the number of blastocysts replaced, thereby affecting implantation rates. A total of 118 pa

In order for ethanol to be competitive with gasoline, the production cost of ethanol must be lower than it is today. One economically crucial step in the production of ethanol from lignocellulosics is refining, since hydrolysis yields dilute glucose solutions which, after fermentation, result in a dilute ethanol solution, 2-3 wt-% ethanol. A technical-economic investigation of various energy-savin

During co-incubation of human inter-alpha-inhibitor (IalphaI) and human tumor necrosis factor-stimulated gene 6 protein (TSG-6) SDS-stable interactions are formed between the two proteins. We have analyzed the products of this reaction and characterized the mechanism of complex formation. Following the incubation seven new bands not previously identified were apparent in SDS-PAGE. Three of these b