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Do the distributional preferences of national infrastructure planners diverge from those of the public?

In this paper, we study how the distributional preferences of planners and the public diverge in the context of national infrastructure planning. To do so, we surveyed a sample of 323 planners working at the Swedish Transport Administration and 2,108 members of the Swedish public. The most striking difference is that planners place a relatively higher value on aggregate benefits than the public. P

Alzheimer Disease Blood Biomarkers in Patients with Out-of-Hospital Cardiac Arrest

Importance: Blood phosphorylated tau (p-tau) and amyloid-β peptides (Aβ) are promising peripheral biomarkers of Alzheimer disease (AD) pathology. However, their potential alterations due to alternative mechanisms, such as hypoxia in patients resuscitated from cardiac arrest, are not known. Objective: To evaluate whether the levels and trajectories of blood p-tau, Aβ42, and Aβ40 following cardiac a

Weak Signal Detection With Low-Bit Quantization in Colocated MIMO Radar

This paper addresses the weak signal detection problem in a massive colocated multiple-input multiple-output (MIMO) radar. To cope with the sheer amount of data produced by the large-scale antennas, a low-bit quantizer is introduced in the sampling process to enable both for hardware limitations and a high detection performance. The generalized likelihood ratio test (GLRT) detector is proposed for

Current-driven insulator-to-metal transition without Mott breakdown in Ca2RuO4

The electrical control of a material's conductivity is at the heart of modern electronics. Conventionally, this control is achieved by tuning the density of mobile charge carriers. A completely different approach is possible in Mott insulators such as Ca2RuO4, where an insulator-to-metal transition (IMT) can be induced by a weak electric field or current. While the driving force of the IMT is poor

ChatGPT applications in medical, dental, pharmacy, and public health education : A descriptive study highlighting the advantages and limitations

Since its public release in November 2022, ChatGPT has gained a widespread attention and received mixed responses in the academia. Promising applications of ChatGPT in university education has been suggested; however, several concerns were raised. The aim of this descriptive study was to investigate the pros and cons of ChatGPT use in medical, dental, pharmacy, and public health education. Based o

High use of pain, depression, and anxiety drugs in hemophilia : more than 3000 people with hemophilia in an 11-year Nordic registry study

Background: Pain is a common feature of hemophilia, but prevalence of depression and anxiety is less studied. Registry data on prescription drugs can provide an objective measure of the magnitude of these complications. Objectives: To identify treatment patterns of prescribed pain, antidepressant, and antianxiety medications compared with those of matched controls in 4 Nordic countries. Methods: T

Synthetic fibrous hydrogels as a platform to decipher cell–matrix mechanical interactions

Cells continuously sense external forces from their microenvironment, the extracellular matrix (ECM). In turn, they generate contractile forces, which stiffen and remodel this matrix. Although this bidirectional mechanical exchange is crucial for many cell functions, it remains poorly understood. Key challenges are that the majority of available matrices for such studies, either natural or synthet

Current-driven writing process in antiferromagnetic Mn2Au for memory applications

Current pulse driven Néel vector rotation in metallic antiferromagnets is one of the most promising concepts in antiferromagnetic spintronics. We show microscopically that the Néel vector of epitaxial thin films of the prototypical compound Mn2Au can be reoriented reversibly in the complete area of cross shaped device structures using single current pulses. The resulting domain pattern with aligne

Evolutionary and Ecological Processes Underlying Geographic Variation in Innate Bird Songs

Ecological and evolutionary processes underlying spatial variation in signals involved in mate recognition and reproductive isolation are crucial to understanding the causes of population divergence and speciation. Here, to test hypotheses concerning the causes of song divergence, we examine how songs of two sister species of Atlantic Forest suboscine birds with innate songs, the Pyriglena fire-ey

Localizing Unsynchronized Sensors With Unknown Sources

We propose a method for sensor array self-localization using a set of sources at unknown locations. The sources produce signals whose times of arrival are registered at the sensors. We look at the general case where neither the emission times of the sources nor the reference time frames of the receivers are known. Unlike previous work, our method directly recovers the array geometry, instead of fi

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Peritoneal dialysis (PD) uses the peritoneal membrane for dialysis. The peritoneal membrane is a thin layer of tissue that lines the abdomen. The lining is used as a filter to help remove extra fluid and poisonous waste from the blood. Everybody is unique. What is normal for one person’s membrane may be very different from another person’s. The kidney care team wants to provide each person with th

A practical and environmentally friendly protocol for synthesis of α-deuterated carboxylic acids

α-deuterated carboxylic acids have been synthesized from the corresponding malonic acids via hydrogen/deuterium exchange and decarboxylation in presence of D2O. The method is general, mild and efficient and does not require organic solvents or other additives. Yields range between 83% and 94% and purification was not necessary. Starting materials were easy accessible and the α-deuterated carboxyli

Modeling cancer’s ecological and evolutionary dynamics

In this didactic paper, we present a theoretical modeling framework, called the G-function, that integrates both the ecology and evolution of cancer to understand oncogenesis. The G-function has been used in evolutionary ecology, but has not been widely applied to problems in cancer. Here, we build the G-function framework from fundamental Darwinian principles and discuss how cancer can be seen th

Quality of life, sense of coherence and occupational balance one year after an occupational therapy intervention for people with depression and anxiety disorders

BACKGROUND: Quality of life (QOL), sense of coherence (SOC) and occupational balance (OB) have been found to increase after rehabilitation among people living with depression and anxiety. However, these aspects have not been investigated over time in participants with different paid work situations, such as being on sick leave or not. OBJECTIVE: To describe and compare the self-rated QOL, SOC and

Enforcing Corporate Opportunity Rules : Antitrust Risks and Antitrust Failures

This paper identifies the potential competitive harm in the enforcement of corporate opportunity rules and shows that antitrust intervention cannot sufficiently address such harm. It suggests that the current antitrust framework is ill-suited to tackle the anticompetitive risks, in particular, regarding effects on innovation. The paper first explains corporate opportunity rules in EU member States

APOE -ε4 modulates the association between regional amyloid deposition and cognitive performance in cognitively unimpaired middle-aged individuals

Purpose: To determine whether the APOE-ε4 allele modulates the relationship between regional β-amyloid (Aβ) accumulation and cognitive change in middle-aged cognitively unimpaired (CU) participants. Methods: The 352 CU participants (mean aged 61.1 [4.7] years) included completed two cognitive assessments (average interval 3.34 years), underwent [18F]flutemetamol Aβ positron emission tomography (PE

Fluorescence excitation enhancement by waveguiding nanowires

The optical properties of vertical semiconductor nanowires can allow an enhancement of fluorescence from surface-bound fluorophores, a feature proven useful in biosensing. One of the contributing factors to the fluorescence enhancement is thought to be the local increase of the incident excitation light intensity in the vicinity of the nanowire surface, where fluorophores are located. However, thi