To elucidate the relationship between cerebrospinal fluid (CSF) total-tau (T-tau) and phosphorylated tau (P-tau) with the tau PET ligand 18F-AV-1451 in Alzheimer's disease (AD), we examined 30 cognitively healthy elderly (15 with preclinical AD), 14 prodromal AD, and 39 AD dementia patients. CSF T-tau and P-tau were highly correlated (R = 0.92, P < 0.001), but they were only moderately associated

The doctoral thesis seeks to discuss the transition between Viking Age and early medieval settlement and the establishment of the historical villages, based on archaeological material collected in Halland. The development is described in terms of three general periods of change: Period 1, c. 800–1000, consisting of farms with three-aisled longhouses. Period 2, c. 1000–1150, a transitional period w

An increasing number of students of various minority and immigrant backgrounds makes greater knowledge of the sources of cross-linguistic influence among bilingual students not only of theoretical value, but also beneficial for improving language teaching and instruction. The aim of this thesis has been to investigate conceptual cross-linguistic influence in functional bilinguals with a focus on i

Objective: To assessmyoepithelium with p63 in fresh breast cancer (BC)tissue samples collected in RNA later for further analysis with NextGeneration Sequencing (NGS) technique. For a better understanding ofthe NGS bulk-analysis, a central part of the sample in RNA-later isformalin-fixed paraffin-embedded to score relative cellularity in % onhematoxylin-eosin (HE) staining (% of invasive cancer, ca

Objective: Estrogen receptor (ER) positive breast cancer (BC) can havean insidious course with disease-relapse decades after primary surgery.New analysis performed on archived formalin-fixed paraffin-embedded(FFPE) tissue are important for disease-management in late BC-relapseand an important tool in BC-research. However, although loss of immunoreactivityin tissue slides after sectioning has been

Particles can be used to stabilize multi-phase systems known as Pickering emulsions. The aim of this thesis was to investigate how starch particles affect emulsion properties. Starch granules were used individually as well as in binary mixtures. To obtain a wide variety of starch properties granules were selected based on botanic variation (quinoa, oat, waxy barley, waxy maize and potato). The pro

This study investigates acoustic and articulatory correlates of South Swedish word accents (Accent 1 vs. 2) – a tonal distinction traditionally associated with F0 timing. The study is motivated by previous findings on (i) the acoustic complexity of tonal prosody and (ii) tonal-articulatory interplay in other languages. Acoustic and articulatory (EMA) data from two controlled experiments are reportThis study investigates acoustic and articulatory correlates of South Swedish word accents (Accent 1 vs. 2) — a tonal distinction traditionally associated with F0 timing. The study is motivated by previous findings on (i) the acoustic complexity of tonal prosody and (ii) tonal-articulatory interplay in other languages.Acoustic and articulatory (EMA) data from two controlled experiments are reporte

The interplay of verbal and visual prominence cues has attracted recent attention, but previous findings are inconclusive as to whether and how the two modalities are integrated in the production and perception of prominence. In particular, we do not know whether the phonetic realization of pitch accents is influenced by co-speech beat gestures, and previous findings seem to generate different pre

Researchers sometime fall into the dummy variable trap. A typical scenario in panel data is when wanting to estimate the effect of a regressor that is time invariant, such as sex or race, and accidentally including cross-section specific fixed effects. The problem here is that the fixed effects and the regressor are collinear, which causes the resulting pooled least squares estimator to break down