Objective: Systemic lupus erythematosus (SLE) predominantly affects women, but previous studies suggest that men with SLE present a more severe disease phenotype. In this study, we investigated a large and well-characterized patient group with the aim of identifying sex differences in disease manifestations, with a special focus on renal involvement. Methods: We studied a Swedish multi-center SLE

We present The Odonate Phenotypic Database (OPD): an online data resource of dragonfly and damselfly phenotypes (Insecta: Odonata). Odonata is a relatively small insect order that currently consists of about 6400 species belonging to 32 families. The database consists of multiple morphological, life-history and behavioral traits, and biogeographical information collected from literature sources. W

Objectives The overall aim of this study was to aggregate the conclusions of all investigations conducted after suicides reported to the supervisory authority in Sweden in 2015, and to identify deficiencies in healthcare found in these investigations; the actions proposed to deal with the deficiencies; the level of the organisational hierarchy (micro-meso-macro) in which the deficiencies and actio

To assess the properties of the quark–gluon plasma formed in ultrarelativistic ion collisions, the ATLAS experiment at the LHC measures a correlation between the mean transverse momentum and the flow harmonics. The analysis uses data samples of lead–lead and proton–lead collisions obtained at the centre-of-mass energy per nucleon pair of 5.02 TeV, corresponding to total integrated luminosities of

What does ‘sexual citizenship’ mean in practice for people with mobility impairments who may need professional support to engage in sexual activity? The book explores this subject through empirical investigation based on case studies conducted in four countries – Sweden, England, Australia and the Netherlands – and develops the abstract notion of ‘sexual citizenship’ to make it practically relevan

Det finns många fördelar med att låta studenter vid högre utbildning gruppvis genomföra projektarbete med öppna frågeställningar. Det finns emellertid problem med att sätta individuella betyg i en kurs som till stor del examineras genom det gruppvisa projektarbetet. I kursen EEMA01 Medicinteknisk design ges valet av undervisningsform naturligt av lärandemålens karaktär men betygssättningen böravsp

Lessons learned in the feedback process are atwo-sided coin that ultimately guide the PhD candidatetowards becoming an independent researcher as well aseducating “reader/docents” in their role as supervisor.Building on a brief literature review, observations from 14interviewed PhD candidates were reflected upon and these arethe suggested lessons learned. The study’s preliminary findingssuggest tha

Increasing interdependencies between critical infrastructures have made these systems more effective, but also more susceptible to cascading failures. In order to reduce the likelihood and consequences of cascading failures, it is essential to develop tools that support incident commander decisions so that an initial failure does not spread to other infrastructures. Here, a framework for generatin

En viktig faktor för studenternas lärande i en kurs är uppgifterna de arbetar med. Idealt ska de träna studenterna på olika kompetenser, belysa teorin på olika sätt och samtidigt motivera och väcka intresse. Sedan några år tillbaka använder vi ett omfattande arbetsmaterial ''Räkna med variation'' för att undervisa i grundläggande sannolikhetslära och statistisk inferens. Vi kommer att presentera a

Colorectal cancer (CRC) is the third most prevalent cancer worldwide causing an estimated 700 000 deaths annually. Different types of treatment are available for patients with advanced metastatic colorectal cancer, including targeted biological agents, such as cetuximab, a monoclonal antibody that targets EGFR. We have previously reported a study indicating multiple levels of interaction between m

This thesis is considering various aspects of electronic transport through quantum dots, with the focus on two or three dots coupled in series.In paper I, we study the impact of electron-electron interactions on transport in a system of triple quantum dots with spin. We show that due to electron-electron scattering processes, transport is possible beyond the common single-particle transmission cha

High frame rate ultrasound imaging is necessary to enable tracking of rapid dynamic events such as the carotid pulse wave velocity. Several studies have shown that it is feasible to use motion tracking methods that are applied on standard ultrasound frame rates also on very high frame rates. However, few studies have addressed the issue of accumulated tracking errors over vast numbers of frames du

In view of the significance, complexity, and difficulty of micromixing in viscous system, coaxial mixers with wide adaptability to viscosity are first combined with micromixing. The effects of feeding position, rotation mode, and impeller type on the micromixing performance of coaxial mixers are investigated numerically with the standard engulfment model and eddy dissipation concept model, and a d

Introduction: A new grading of exercise capacity during bicycle stress testing has been proposed in Sweden based on the new reference material (‘the Kalmar material’), which has not been validated. We aimed to examine the prognostic information of the new grading of exercise capacity during exercise stress testing. Methods: Data on all bicycle exercise tests performed at the Department of Clinical

Emerging theoretical concepts for quantum technologies have driven a continuous search for structures where a quantum state, such as spin, can be manipulated efficiently. Central to many concepts is the ability to control a system by electric and magnetic fields, relying on strong spin-orbit interaction and a large g-factor. Here, we present a mechanism for spin and orbital manipulation using smal

These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often undermine immunological data. Notably, there are comprehensive sections of all major immune cell types with helpful Tables detailing phenotypes in mu

Epigenetic changes may contribute substantially to risks of diseases of aging. Previous studies reported seven methylation variable positions (MVPs) robustly associated with incident type 2 diabetes mellitus (T2DM). However, their causal roles in T2DM are unclear. In an incident T2DM case-cohort study nested within the populationbased European Prospective Investigation into Cancer and Nutrition (E

A review concerning road tunnel fire safety and risk is presented. In particular different perspectives and methodson safety and risk are discussed. Road tunnel fire safety usually involves high uncertainty and high-stakes decisions.Thus, a wider group of stakeholders and different types of knowledge should be included in the fire safety analysisand evaluation, than what is required by technical r

Bastin et al (Reports, 5 July 2019, p. 76) claim that 205 gigatonnes of carbon can be globally sequestered by restoring 0.9 billion hectares of forest and woodland canopy cover. Reinterpreting the data from Bastin et al, we show that the global land area actually required to sequester human-emitted CO2 is at least a factor of 3 higher, representing an unrealistically large area.