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Dialectic of Two Cultures : Edward Albee, C. P. Snow, and Who's Afraid of Virginia Woolf? as Dramatized Epistemology

Since its publication and first performance, Edward Albee’s Who’s Afraid of Virginia Woolf? (1962) has often been interpreted with regard to the theme of truth and illusion. A less studied but nonetheless important aspect of the play concerns its relation to C. P. Snow’s concept of the “two cultures.” This article argues for the convergence of these two discussions, resulting in an epistemological

The Demographic Costs of Sexually Antagonistic Selection in Partially Selfing Populations

When selection differs between the sexes, genes expressed by both males and females can experience sexually antagonistic (SA) selection, where beneficial alleles for one sex are deleterious for the other. Classic population genetics theory has been fundamental to understanding how and when SA genetic variation can be maintained by balancing selection, but these models have rarely considered the de

Acute Stress among Nurses in Sweden during the COVID-19 Pandemic

Sweden was hit hard in the beginning of the COVID-19 pandemic with deaths per capita among the highest in Europe. The pandemic was a stressful time especially for healthcare workers caring for COVID-19 patients. Various studies have evaluated whether nurses caring for these patients had higher levels of acute stress, but typically with measures that either used older DSM-IV criteria for Acute Stre

Tau biomarkers in Alzheimer's disease : towards implementation in clinical practice and trials

Background: Deposition of tau aggregates is a pathological hallmark of Alzheimer's disease that is closely linked both spatially and temporally to emergence of neurodegeneration and manifestation of clinical symptoms. There is an urgent need for accurate PET, CSF, and plasma biomarkers of tau pathology to improve the diagnostic process in clinical practice and the selection of participants and mon

Doing well-being : Self-reported activities are related to subjective well-being

Activities and Subjective Well-Being (SWB) have been shown to be intricately related to each other. However, no research to date has shown whether individuals understand how their everyday activities relate to their SWB. Furthermore, the assessment of activities has been limited to predefined types of activities and/or closed-ended questions. In two studies, we examine the relationship between sel

Population Games on Dynamic Community Networks

In this letter, we deal with evolutionary game-theoretic learning processes for population games on networks with dynamically evolving communities. Specifically, we propose a novel mathematical framework in which a deterministic, continuous-time replicator equation on a community network is coupled with a closed dynamic flow process between communities, in turn governed by an environmental feedbac

Unilateral or Bilateral Retroperitoneal Lymph Node Dissection in Nonseminoma Patients with Postchemotherapy Residual Tumour? Results from RETROP, a Population-based Mapping Study by the Swedish Norwegian Testicular Cancer Group

BACKGROUND: The distribution of retroperitoneal lymph node metastases for patients with nonseminoma and a residual tumour of 10-49 mm in a population-based setting is unknown. This information is needed to justify selection of patients for a unilateral template resection. OBJECTIVE: To describe the location of retroperitoneal metastases and recurrences in patients with nonseminoma germ cell tumour

Thermodynamic and exergoeconomic analysis of a novel CO2 based combined cooling, heating and power system

In this paper, a novel combined cooling, heating and power (CCHP) system consisting of a supercritical carbon dioxide (sCO2) power cycle, a transcritical carbon dioxide (tCO2) power cycle with a carbon dioxide based refrigeration cycle, and a direct heating (DH) system is proposed. In the novel system, the waste heat from sCO2 power cycle is recovered by the tCO2 power cycle to generate additional

Low vitamin d levels and frailty status in older adults : A systematic review and meta-analysis

Serum vitamin D deficiency is widespread among older adults and is a potential modifiable risk factor for frailty. Moreover, frailty has been suggested as an intermediate step in the association between low levels of vitamin D and mortality. Hence, we conducted a systematic review of the literature and meta-analysis to test the possible association of low concentrations of serum 25-hydroxyvitamin

The impact of donor type on the outcome of pediatric patients with very high risk acute lymphoblastic leukemia. A study of the ALL SCT 2003 BFM-SG and 2007-BFM-International SG

Allogeneic HSCT represents the only potentially curative treatment for very high risk (VHR) ALL. Two consecutive international prospective studies, ALL-SCT-(I)BFM 2003 and 2007 were conducted in 1150 pediatric patients. 569 presented with VHR disease leading to any kind of HSCT. All patients >2 year old were transplanted after TBI-based MAC. The median follow-up was 5 years. 463 patients were tran

Particle-size-dependent acoustophoretic motion and depletion of micro- and nano-particles at long timescales

We present three-dimensional measurements of particle-size-dependent acoustophoretic motion of micropar- ticles with diameters from 4.8 μm down to 0.5 μm suspended in either homogeneous or inhomogeneous fluids inside a glass-silicon microchannel and exposed to a standing ultrasound wave. To study the crossover from radiation force dominated to streaming dominated motion as the particle size is dec