The incidence of narcolepsy type 1 (NT1) increased in Sweden following the 2009-2010 mass-vaccination with the influenza Pandemrix-vaccine. NT1 has been associated with Human leukocyte antigen (HLA) DQB1*06:02 but full high-resolution HLA-typing of all loci in vaccine-induced NT1 remains to be done. Therefore, here we performed HLA typing by sequencing HLA-DRB3, DRB4, DRB5, DRB1, DQA1, DQB1, DPA1

BACKGROUND AND OBJECTIVES: Kidd blood group system consists of two major antigens: Jka and Jkb . Both the antigens are absent in individuals typed as Jknull and may develop clinically significant anti-Jk3 antibody. Screening donors for provision of Jknull blood is an ongoing task for blood centres with Jknull blood units kept frozen for specific requirements. In 2016, we discovered a previously ty

Free plasma thyroxine (FT4) levels were measured in coho salmon, Oncorhynchus kisutch, during parr-smolt transformation (smoltification) using an equilibrium dialysis system followed by a radioimmunoassay. The FT4 data were correlated to total plasma thyroxine (TT4), triiodothyronine (TT3), and growth hormone (GH). Plasma samples were taken weekly from early April to late May, when the salmon wher

Vegetation growth in Soil and Water Assessment Tool (SWAT) is a crucial process for quantifying ecohydrological modelling, as it influences evapotranspiration, interception, soil erosion and biomass production. The simplified version of Environmental Policy Integrated Climate (EPIC) in SWAT was originally designed for temperate regions and naturally based on temperature to simulate growth cycles

Abstract: This study aims to investigate separate and combined impacts of land-use and climate variability on hydrological components in the Johor River Basin (JRB), Malaysia. The Mann-Kendall and Sen’s slope tests were applied to detect the trends in precipitation, temperature and streamflow of the JRB. The Soil and Water Assessment Tool (SWAT) was calibrated and validated using measured monthly

Two Tropical Rainfall Measuring Mission (TRMM) Multisatellite Precipitation Analysis (TMPA) products i.e. 3-hourly TRMM 3B42 and monthly 3B43 data were validated using 39 rain gauge stations in the Caspian Sea Region (CSR) in Iran with complex topography. The period 1999-2003 were selected. The validations were performed at monthly and annual scales. Results showed that both TRMM 3B42 and 3B43 can

OBJECTIVES: Preeclampsia (PE) is a common pregnancy-related disorder associated with cardiovascular long-term disease. Eighty percent are late-onset PE, occurring after 34 gestational weeks, and can present with severe symptoms. Magnitude and reversibility rate of maternal cardiovascular changes after severe late-onset PE have not been characterized. This study therefore evaluated longitudinal dyn

Embryonal tumours with multilayered rosettes (ETMRs) are aggressive paediatric embryonal brain tumours with a universally poor prognosis1. Here we collected 193 primary ETMRs and 23 matched relapse samples to investigate the genomic landscape of this distinct tumour type. We found that patients with tumours in which the proposed driver C19MC2–4 was not amplified frequently had germline mutations i

The Eurozone crisis has meant slow growth, rising unemployment, and social unrest. This column gauges the impact of all this on European citizens‘ opinions about the euro and EU institutions. Using Eurobarometer surveys, the authors find that, within the Eurozone, the crisis has only marginally lowered support for the euro but has led to a sharp fall in public trust in the ECB.