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Flow cytometric DNA ploidy analysis of soft tissue sarcomas. A comparative study of preoperative fine needle aspirates and postoperative fresh tissues and archival material

Flow cytometric (FCM) DNA ploidy measurements on frozen fresh samples of soft tissue sarcomas were compared with the corresponding analyses on preoperative fine needle aspirates and postoperative formalin-fixed archival tissues from the same tumors. A concordance in ploidy status (diploid versus non-diploid) was obtained for 63% of the fresh tissue-fine needle aspiration (FNA) sample comparisons a

Impact of DNA amplification on gene expression patterns in breast cancer

Genetic changes underlie tumor progression and may lead to cancer-specific expression of critical genes. Over 1100 publications have described the use of comparative genomic hybridization (CGH) to analyze the pattern of copy number alterations in cancer, but very few of the genes affected are known. Here, we performed high-resolution CGH analysis on cDNA microarrays in breast cancer and directly c

Implicit integration of plasticity models for granular materials

A stress integration algorithm for granular materials based on fully implicit integration with explicit updating is presented. In the implicit method the solution makes use of the gradient to the potential surface at the final stress state which is unknown. The final stress and hardening parameters are determined solving the non-linear equations iteratively so that the stress increment fulfills th

Företag, regioner och internationell konkurrens : Om regionala resursers betydelse

The overall purpose of this thesis is to study regional variation in the international competitiveness (export capacity, market orientation and production aboard) of Swedish manufacturing industry, and to contribute to explaination of this variation. The explanation is sought for in differences in regional production milieu as well as in differences in localization of industrial sectors and claims

Pristane, a non-antigenic adjuvant, induces MHC class II-restricted, arthritogenic T cells in the rat.

Pristane-induced arthritis (PIA) in rats, a model for rheumatoid arthritis (RA), is a T cell-dependent disease. However, pristane itself is a lipid and unable to form a stable complex with a MHC class II molecule. Therefore, the specificity and function of the T cells in PIA are as unclear as in rheumatoid arthritis. In this study, we show that activated CD4+ alphabetaT cells, which target periphe

The Alevi-Bektasi Legacy: Problems of Acquisition and Explanation

Popular Abstract in Swedish Det mystika arvet: om konsten att erhålla och förklara det (och förstå litegrann): Ett turkiskt exempel.Mystics and amateur politicians in the margin of Turkish society. The specific case of marginalisation in the specific context of my choice provides a wealth of details to be accounted for. All details taken together are real life itself and can thus not be accounted for in a book. Enough can be said, however, about marginalisation in general in order for a meaningful discussion to take place. Bu

Measurements and analysis of a MIMO macrocell outdoor-indoor scenario

Narrowband MIMO channel measurements at 1947 MHz have been performed in an urban macrocellular outdoor-indoor scenario. The spatial characteristics of the channel have been analyzed, showing an angular spread of 5-10° at the base station and 30-60° at the mobile station. The maximum theoretical capacity that the channel can support has been evaluated for various antenna spacings and number of ante

Rigid indenter excitation of plates

The paper presents expressions for the point mobility of infinite plates driven by a completely rigid indenter. The problem is of general interest in connection with the excitation and transmission of structure-borne sound. The indenter is assumed to be circular, weightless, and stiff compared with the plate. A rigid indenter is assumed to provide a better approximation of the actual situation tha

Extensible Compiler Construction

Popular Abstract in Swedish Automatisk analys av programkod är ett kärnområde inom datavetenskap. Det mest typiska verktyget inom detta område är en kompilator som översätter källkod till maskinkod, men det finns många likartade verktyg, exempelvis översättning mellan språkdialekter, kontroll av kodkonventioner samt automatisk omstrukturering av kod. Eftersom dessa verktyg gör liknande analyser fiProcessing of programs is a core area in computer science. A compiler that translates source text to machine language is the most well-known kind of tool in this area, but there are numerous other kinds of related applications: source-to-source translators, refactoring tools, reengineering tools, metrics tools, consistency checkers, etc. These tools perform similar analyses and can therefore benef

Life-history evolution in harvested populations: the role of natural predation

Models and experiments of the evolution of age- and/or size-at-maturation in response to population harvesting have consistently shown that selective harvesting of older and larger individuals can cause earlier maturation. These predictions, however, are all based on single-species considerations and thus crucially neglect the selective forces caused or mediated by species interactions. Here we de

Social mobility, marital status, and mortality risk in an adult life course perspective: The Malmo preventive project

Aims: Adverse social factors predict increased mortality. This study aimed to assess the influence of social class and marital status on mortality, adding an adult life course perspective. Methods: In total, 32,907 males and 20,204 females were evaluated based on census data in Malmo, Sweden. Of these subjects, 22,444 males and 10,902 females also took part in health screening. The main outcomes w

A 9-DOF Tractor-Semitrailer Dynamic Handling Model for Advanced Chassis Control Studies

A nonlinear dynamic handling model for a tractor-semitrailer combination vehicle is presented in this report. The equations of motion are derived from the fundamental equations of dynamics in Euler's formulation without approximations. The model is modular in the sense that it is easy to change axle configuration, tyre model, suspension model, or to add new features. The primary aim of the model i

Whey protein adsorption onto steel surfaces - effect of temperature, flow rate, residence time and aggregation

Whey protein adsorption on stainless steel surfaces was investigated by in situ ellipsometry under well-defined flow conditions and protein solution residence times. The size distribution in solution of the protein aggregates formed under the same conditions was determined by dynamic light scattering. The adsorption was performed at 72 degrees C and 85 degrees C which is below and above the unfold

Eight-Year Exploration of Shrinkage in High-Performance Concrete.

In this paper an experimental and analytical exploration on the effect of water-binder ratio (w/b), silica fume and age on autogenous, carbonation, drying and total shrinkage of High-Performance Concrete (HPC) is outlined. Eight types of HPC were studied. Carbonation, internal relative humidity (RH) and strength were studied on specimens from the same batch of HPC that was used in the studies of s

Regional cerebral blood flow in normal man during insulin-induced hypoglycemia and in the recovery period following glucose infusion

The effect of moderate hypoglycemia (p-glucose, 2.0 +/- 0.3 mmol/L; mean +/- SD) on regional cerebral blood flow (rCBF) was studied in a group of 10 healthy, right-handed men (aged 23 to 28 years) using an intravenous xenon 133 single photon emission computed tomography technique (SPECT). After 10 minutes of hypoglycemia, global CBF had increased to 46.3 +/- 9.6 mL/100 g/min compared with the init