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A Simple Assessment of the Global Long Term Supply of the Rare Earth Elements by Using a System Dynamics Model
Our simple dynamic-simulation model shows that the global supply of Rare Earth Elements is limited for meeting the future demands of new technologies. Unless improved recycling policies are adapted strategic elements may become scarce in the next half-century as a result of a “peak Rare Earths Elements” phenomenon. The model results also show that the market alone cannot solve the resource-ineffic
In vivo evidence for a differential contribution of striatal and nigral D1 and D2 receptors to l-DOPA induced dyskinesia and the accompanying surge of nigral amino acid levels
Evidence for an involvement of striatal D1 receptors in levodopa-induced dyskinesia has been presented whereas the contribution of striatal D2 receptors remains controversial. In addition, whether D1 and D2 receptors located in the substantia nigra reticulata shape the response to levodopa remains unknown. We therefore used dual probe microdialysis to unravel the impact of striatal and nigral D1 o
Age-dependent effect of obestatin on intestinal contractility in Wistar rats
Obestatin is a 23-amino acid peptide encoded by the ghrelin gene. We have investigated the effect of obestatin on intestinal contractility in rats ranging from the suckling period till adolescence. Duodenal and middle jejunum whole-thickness preparations from neonatal and adult rats were studied in an organ bath, for isometric recording under treatment with obestatin (1 mu mol L-1) in the presence
Development and evaluation of the aerosol dynamics and gas phase chemistry model ADCHEM
The aim of this work was to develop a model suited for detailed studies of aerosol dynamics, gas and particle phase chemistry within urban plumes, from local scale (1x1 km(2)) to regional scale. This article describes and evaluates the trajectory model for Aerosol Dynamics, gas and particle phase CHEMistry and radiative transfer (AD-CHEM). The model treats both vertical and horizontal dispersion p
Familial aggregation of stroke amongst young patients in Lund Stroke Register.
The known monogenic forms of stroke are rare. The aim of this study was to analyze pedigrees of young stroke patients regarding possible monogenic cerebrovascular disease and to evaluate the possibility of genetic stroke in these families. This may contribute to a better understanding of disease mechanism in stroke.
Effects of Communication with Non-witnesses on Eyewitnesses' Recall Correctness and Meta-cognitive Realism
In forensic contexts it is common that witnesses retell and discuss the experienced event many times. It is of forensic importance to understand how this influences memory and meta-memory. Eighty-nine participants viewed a short film and were assigned to one of four conditions: (1) Laboratory discussion (five discussions of the event with a confederate), (2) Family discussion (five discussions of
Expression and localization of serotonin receptors in human breast cancer.
The aim of this study was to examine the expression of serotonin receptors in patients with breast cancer and to explore their utility as diagnostic and prognostic markers. Immunohistochemical analysis was performed to examine the expression of serotonin (5-HT) receptor subtypes 1A, 1B, 2B and 4 in a tissue microarray containing tumor specimens from 102 patients. Statistical analysis was performed
Temperature-Dependent Infrared Spectroscopy of Proton-Conducting Hydrated Perovskite BaInxZr1-xO3-x/2 (x=0.10-0.75)
We investigate the temperature dependence of the O-H stretch band in the infrared absorbance spectra of the proton-conducting hydrated perovskites BaInxZr1-xO3-x/2 (x = 0.10-0.75) over the temperature range -160 to 350 degrees C. Upon increasing temperature from -160 to 30 degrees C, we show that there is a redistribution of protons from nonsymmetrical structural configurations, such as Zr-OH-In a
Neurological prognostication after cardiac arrest-Recommendations from the Swedish Resuscitation Council.
Cardiopulmonary resuscitation is started in 5000 victims of out-of-hospital cardiac arrest in Sweden each year and the survival rate is approximately 10%. The subsequent development of a global ischaemic brain injury is the major determinant of the neurological prognosis for those patients who reach the hospital alive. Induced hypothermia is a recommended treatment after cardiac arrest and has bee
Delineating Transcriptional Networks of Prognostic Gene Signatures Refines Treatment Recommendations for Lymph Node-negative Breast Cancer Patients.
The majority of women diagnosed with lymph node-negative breast cancer are unnecessarily treated with damaging chemotherapeutics following surgical resection. This highlights the importance of understanding and more accurately predicting patient prognosis. Here, we define the transcriptional networks regulating well-established prognostic gene expression signatures. We find that the same set of tr
Reduction of off-state drain leakage in InGaAs-based metal-oxide-semiconductor field-effect transistors
Off-state drain leakage current has been investigated for InGaAs-based metal-oxide-semiconductor field-effect transistors with different drain configurations, InGaAs, and InP, respectively. The introduction of an InP drain presents a lower leakage current compared to InGaAs drain devices. From temperature dependent measurements, the leakage current mechanisms have been differentiated, and the role
Biological applications of a new isothermal calorimeter that simultaneously measures at four temperatures
Isothermal calorimetry is a powerful technique for the study of kinetics of physical, chemical, and biological processes, for example, of their temperature dependence. A new heat conduction calorimeter that simultaneously makes measurements on four samples at four different temperatures is presented in this article. Results from tests with four biological systems (milk fermentation, carrot juice s
Selling books and digital files : A comparative study of the sales of books and e-books in Sweden
The book trade is going through wide-ranging changes pushed by digital technology and e-books, and there is considerable concern over the consequences this will have for literature, culture and reading. The article proposes that the present development can be compared with similar changes in the book trade in the past, and that the effects of sales of e-books might not be all-encompassing as has b
Probing Confined Phonon Modes by Transport through a Nanowire Double Quantum Dot
Strong radial confinement in semiconductor nanowires leads to modified electronic and phononic energy spectra. We analyze the current response to the interplay between quantum confinement effects of the electron and phonon systems in a gate-defined double quantum dot in a semiconductor nanowire. We show that current spectroscopy of inelastic transitions between the two quantum dots can be used as
Impact of colostrum and plasma immunoglobulin intake on hippocampus structure during early postnatal development in pigs.
The first milk, colostrum, is an important source of nutrients and an exclusive source of immunoglobulins (Ig), essential for the growth and protection from infection of newborn pigs. Colostrum intake has also been shown to affect the vitality and behaviour of neonatal pigs. The objective of this study was to evaluate the effects of feeding colostrum and plasma immunoglobulin on brain development
Maternal body mass index and duration of labor
Objective: To evaluate whether the duration of the active phase of labor is associated with maternal body mass index (BMI), in nulliparous women with spontaneous onset of labor. Study design: Historical prospective cohort study including 63,829 nulliparous women with a singleton pregnancy and a spontaneous onset of labor, who delivered between January 1, 1995 and December 31, 2009. Data were colle
Reaction profile in patch testing with allergens formed during vulcanization of rubber.
Vulcanization of rubber changes its allergen pattern.
Association of genetic polymorphisms in ESR2, HSD17B1, ABCB1, and SHBG genes with colorectal cancer risk
The incidence rates and relative risks for colorectal cancer (CRC) are higher in men than in women. Sex steroids may play a role in this gender-associated difference in CRC risk. This study was conducted to explore the relationship of single nucleotide polymorphisms (SNPs) in steroid hormone signaling (ESR1, ESR2, PGR, NR1I2, and SHBG), phase I-and II-metabolizing enzyme (COMT, HSD17B1, CYP1A1, CY
Exposure to persistent organic pollutants and sperm sex chromosome ratio in men from the Faroe Islands.
People in the Arctic as well as fishermen on the polluted Swedish east coast are highly exposed to persistent organic pollutants (POPs). These compounds have been shown to affect the sperm Y:X chromosome ratio. In present study, the aim was to investigate whether polychlorinated biphenyl (PCB) congeners and 1,1,-dichloro-2,2,-bis(p-chlorophenyl)ethane (p,p'-DDE) influence sperm sex chromosome rati