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How to avoid glucose degradation products in peritoneal dialysis fluids

Objective: The formation of glucose degradation products (GDPs) during sterilization of peritoneal dialysis fluids (PDFs) is one of the most important aspects of biocompatibility of glucose-containing PDFs. Producers of PDFs are thus trying to minimize the level of GDPs in their products. 3,4-Dideoxyglucosone-3-ene (3,4-DGE) has been identified as the most bioreactive GDP in PDFs. It exists in a t

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Abstract in German Handekzeme sind sehr häufig, können verschiedene Ursachen haben und trotz einer Vielzahl von Behandlungsoptionen, die von topischen Kortikosteroiden über Phototherapie bis zur oralen Gabe von Ciclosporin und Retinoiden reichen, eine therapeutische Herausforderung darstellen. In den führenden Literaturdatenbanken (ldquorCochraneldquo, ldquorMEDLINEldquo, ldquorEmbaseldquo, ldquor

Skola utan timplan - om lärares tolkning av uppdraget i en mål- och resultatstyrd skola

The issue of this article is the direction of the Swedish compulsory school. The article is based upon the results of a longitudinal study of four schools participating in a probation, initiated by the Swedish government, where they are allowed to work without the timetable. What regulates school activity when there is no timetable that prescribes the amount of time for each subject? What are the

Multivariate on-line monitoring: challenges and solutions for modern wastewater treatment operation

In this paper, a number of challenges, which need to be overcome if multivariate monitoring of wastewater treatment operation is to be successful, are presented. For each challenge, one or several solutions are discussed. The methodologies are illustrated using an example from full-scale wastewater treatment operation. Some guidelines regarding choices of methods and implementation aspects are giv

Tracking of proinflammatory collagen-specific T cells in early and late collagen-induced arthritis in humanized mice

Rheumatoid arthritis is a chronic inflammatory disease associated with certain HLA-DR4 subtypes. The target autoantigen(s) is unknown, but type II collagen (CII) is a candidate, with a single immunodominant DR4-restricted 261-273 T cell epitope (CII(261273)). In the present study, we have prepared HLA-DR4:CII(261-273) tetramers and analyzed peripheral blood, lymph node, and synovial fluid cells fr

CHICSi - a compact ultra-high vacuum compatible detector system for nuclear reaction experiments at storage rings. II. Detectors

We describe the detectors for identification of charged particles and fragments in CHICSi, a large solid angle multitelescope system mounted inside an ultra-high vacuum (UHV), cluster-jet target chamber. CHICSi performs nuclear reaction experiments at storage rings. The telescopes consist of a first very thin, 10-14 mum Si detector, a second 300 mum (or possibly 500 pm) ion implanted Si detector s

Acoustically driven emission of light in granular and layered semiconductors: recent advances and future prospects

Acoustic driving techniques can produce luminescence in semiconductors quite efficiently. A mixture of grain particles, for example, emits light when driven by sufficiently intense acoustic fields. This effect is therefore particularly interesting for exploring the dynamics of granular solids. By applying this novel technique, further insight is gained when monitoring the driving-induced evolution

Modeling the effects of knots in Structural Timber

The main purpose of the pursued research is to increase knowledge of the effects of knots in structural timber so that characteristics of weaker timber may be determined and applied to improve current grading techniques. In the process, a three-dimensional fiber paradigm was established, which describes variations of local principle material axes in timber containing knots. The adaptability of the

A Genome-Wide Scan in Families With Maturity-Onset Diabetes of the Young: Evidence for Further Genetic Heterogeneity.

Maturity-onset diabetes of the young (MODY) is a heterogeneous single gene disorder characterized by non–insulin-dependent diabetes, an early onset and autosomal dominant inheritance. Mutations in six genes have been shown to cause MODY. Approximately 15–20% of families fitting MODY criteria do not have mutations in any of the known genes. These families provide a rich resource for the identificat

Treatment of warfarin-associated intracerebral hemorrhage: Literature review and expert opinion

Wider use of oral anticoagulants has led to an increasing frequency of warfarin-related intracerebral hemorrhage (ICH). The high early mortality of approximately 50% has remained stable in recent decades. In contrast to spontaneous ICH, the duration of bleeding is, 12 to 24 hours in many patients, offering a longer opportunity for Intervention. Treatment varies widely, and optimal therapy has yet

The management of infections in children in general practice in Sweden: A repeated 1-week diagnosis-prescribing study in 5 counties in 2000 and 2002

A diagnosis-prescribing study was performed in 5 Swedish counties during 1 week in November in 2000 and repeated in 2002. The aim of the present study was to analyse data for children 0-15 y of age who consulted a general practitioner with symptoms of an infection. During the 2 weeks studied, 4049 children were consulted. Respiratory tract infections (RTI) were the predominant diagnoses, above all

Is HRCA a concept which summarizes the innovation work in the most intrinsic parts of firms during the last decades?: Why does HRCA still hit values and principles, even if it has had time to ripen?

Abstract in UndeterminedPurpose – The purpose of this paper is to give an overview of the concept of HRCA – human resource costing and accounting – and to encourage debate in this research area. The knowledge dimensions or research areas of HRCA could be described by using a simple model or classification scheme. The model could be seen as a way to describe the links between accounting and financi

Genome-wide comparison of phage M13-infected vs. uninfected Escherichia coli

To identify Escherichia coli genes potentially regulated by filamentous phage infection, we used oligonucleotide microarrays. Genome-wide comparison of phage M13-infected and uninfected E. coli, 2 and 20 min after infection, was performed. The analysis revealed altered transcription levels of 12 E. coli genes in response to phage infection, and the observed regulation of phage genes correlated wit