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Activated porcine embryonic brain endothelial cells induce a proliferative human T-lymphocyte response

Transplantation of allogeneic embryonic neural tissue is a potential treatment for patients with Parkinson's and Huntington's diseases. The supply of human donor tissue is limited, and alternatives such as the use of animal (e.g., porcine) donor tissue are currently being evaluated. Before porcine grafts can be used clinically, strategies to prevent neural xenograft rejection must be developed. Kn

Structure and Bonding of Ethylene Oxide on Si(100)

The bonding configuration and electronic structure of ethylene oxide adsorbed on Si(100)-(2 x 1) is investigated with fully polarization resolved X-ray absorption spectroscopy as well as with core level and valence band photoemission spectroscopy. Ethylene oxide is found to adsorb via a ring-opening reaction, where the molecule forms a five-membered ring together with the silicon surface dimer ato

Oxidation Catalysis on YBa2Cu3O6 + x

Mild oxidation catalysts are used to product a wide range industrial chemicals from hydrocarbons, whereas deep oxidation catalysts yield CO2 and are becoming important in the cleaning of emissions from combustion of carbonaceous fuels. Here we report on a catalyst1 that facilitates both mild and deep oxidation of toluene in the presence of molecular oxygen and ammonia. At low partial pressures of

Resonant photoemission study of La1-xSrxMnO3 single crystals

A feature at a binding energy of similar to 2.5eV which has not previously been discussed in the literature is observed in the photoemission spectra of the valence band of La1-xSrxMnO3 single crystals. To reveal the origin of this feature measurements of resonant photoemission on La1-xSrxMnO3 were performed as well as absorption spectra at the La N and Mn L-2,L-3 edges at liquid nitrogen and room

Crystal structure and biological implications of a bacterial albumin binding module in complex with human serum albumin

Many bactericide species express surface proteins that interact with human serum albumin (HSA). Protein PAB from the anaerobic bacterium Finegoldia magna ( formerly Peptostreptococcus magnus) represents one of these proteins. Protein PAB contains a domain of 53 amino acid residues known as the GA module. GA homologs are also found in protein G of group C and G streptococci. Here we report the crys

Carbon-Phosphorus Bond Activation of Tri(2-thienyl)phosphine at Dirhenium and Dimanganese Centers

Reaction of [Re-2(CO)(9)(NCMe)] with tri(2-thienyl)phosphine (PTh3) in refluxing cyclohexane affords three substituted dirhenium complexes: [Re-2(CO)(9)(PTh3)] (1), [Re-2(CO)(8)(NCMe)(PTh3)] (2), and [Re-2(CO)(8)(PTh3)(2)] (3). Complex 2 was also obtained from the room-temperature reaction of [Re-2(CO)(8)(NCMe)(2)] with PTh3 and is an unusual example in which the acetonitrile and phosphine ligands

Electrochemical characterization and redox behavior of Nb-doped SrTiO3

Sr-vacancy compensated Nb-doped SrTiO3 with the nominal composition Sr0.94Ti0.9Nb0.1O3 has been evaluated as a solid oxide fuel cell (SOFC) anode material in terms of redox stability and electrochemical properties. Sr0.94Ti0.9Nb0.1O3 has been synthesized with a recently developed modified glycine-nitrate process. The phase purity and redox behavior have been analyzed with XRD and TGA. The electroc

Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort study

Background Alzheimer's disease (AD) pathology is common in patients with amnestic mild cognitive impairment (aMCI) without dementia, but the prevalence of AD pathology in patients with subjective cognitive impairment (SCI) and non-amnestic mild cognitive impairment (naMCI) is unknown. AD is characterised by decreased CSF concentrations of A beta(42) and increased concentrations of tau. We investig

Mutation analysis of SLC7A9 in cystinuria patients in Sweden

Cystinuria is an autosomal recessive disorder characterized by increased urinary excretion of cystine and dibasic amino acids, which cause recurrent stone formation in affected individuals. Three subtypes of cystinuria have been described (type I, II, and III): type I is caused by mutations in the SLC3A1 gene, whereas nontype I (II and III) has been associated with SLC7A9 mutations. Of the 53 pati

Cutaneous innervation before and after one treatment period of acupuncture.

BACKGROUND: The effect of acupuncture on nociceptive pain is well documented, but effects on nociceptive itch have been contradictory. OBJECTIVES: To evaluate possible effects of acupuncture on the occurrence, distribution and function of sensory nerve fibres in human skin. METHODS: Ten subjects were treated by inserting 10 acupuncture needles subcutaneously at the upper lateral aspect of one butt

Lung fractional moving blood volume in normally grown and growth restricted foetuses.

Objective: To examine foetal lung blood perfusion using power Doppler ultrasound (PDU) and to compare fractional moving blood volume (FMBV) and mean pixel intensity (MPI) estimations in the lungs of normally grown (NG) foetuses and foetuses with intrauterine growth restriction (IUGR) and also to correlate foetal lung FMBV and MPI with respiratory complications after birth. Methods: Lungs of 47 NG

The development of a short measure of physical function for hip OA HOOS-Physical Function Shortform (HOOS-PS): an OARSI/OMERACT initiative

Objective: To derive a cross-culturally valid, short measure of physical function using function subscales (daily living and sports and recreation) of the Hip disability and Osteoarthritis Outcome Score (HOOS). Methods: Rasch analysis was conducted on data from individuals from multiple countries who had hip osteoarthritis (OA). Fit of the data to the Rasch model was evaluated by model chi(2) and

The mechanism of bacterial infection by filamentous phages involves molecular interactions between TolA and phage protein 3 domains

The early events in filamentous bacteriophage infection of gram-negative bacteria are mediated by the gene 3 protein (g3p) of the virus. This protein has a sophisticated domain organization consisting of two N-terminal domains and one C-terminal domain, separated by flexible linkers. The molecular interactions between these domains and the known bacterial coreceptor protein (TolA) were studied usi

On the finiteness of Gröbner bases computation in quotients of the free algebra

We investigate, for quotients of the non-commutative polynomial ring, a property that implies finiteness of Gröbner bases computation, and examine its connection with Noetherianity. We propose a Gröbner bases theory for our factor algebras, of particular interest for one-sided ideals, and show a few applications, e.g. how to compute (one-sided) syzygy modules.