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Positive Network Systems : Heuristic Methods and Opinion Dynamics

The analysis of interconnected systems is a large and growing field, with successful applications in a wide range of natural and synthesized systems. Biomolecular networks, power grids and human social dynamics have all been the subject of study through the lens of network dynamics, with impressive results. The work presented in this thesis takes the form of four research papers all focusing in di

Measurement properties of the Minimal Insomnia Symptom Scale (MISS) among cardiac arrest survivors – A Rasch evaluation study

IntroductionCardiac arrest (CA) survivors often face significant health challenges, including insomnia, which can adversely affect their health-related quality of life. The Minimal Insomnia Symptom Scale (MISS) is a brief, self-reported instrument designed to screen for insomnia. This study aimed to identify the measurement properties of the MISS in CA survivors and to explore a relevant cut-off sIntroductionCardiac arrest (CA) survivors often face significant health challenges, including insomnia, which can adversely affect their health-related quality of life. The Minimal Insomnia Symptom Scale (MISS) is a brief, self-reported instrument designed to screen for insomnia. This study aimed to identify the measurement properties of the MISS in CA survivors and to explore a relevant cut-off s

Location

Encyclopedia entry on location as a theoretical and practical concept.

Different forms and sources of iron in relation to colorectal cancer risk: a case-control study in China

Few studies have examined the association of various types of Fe with colorectal cancer risk. The aim of this study was to investigate different forms and sources of Fe in relation to colorectal cancer risk in a Chinese population. A total of 2138 patients with colorectal cancer and 2144 sex- and age-matched (5-year interval) controls were recruited from July 2010 to November 2017. Dietary informa

Effects of chocolate-based products intake on blood glucose, insulin and ghrelin levels and on satiety in young people: a cross-over experimental study

This cross-over experimental study aimed to examine the effects of filled chocolate consumption on blood glucose, insulin and ghrelin levels in 20 volunteers. After a one-week run-in period, study participants consumed two chocolate-based products, the tested biscuit or water for 21 days as a morning snack. After a two-week wash-out period, participants consumed another tested food for another 21

IPECAD Modeling Workshop 2023 Cross-Comparison Challenge on Cost-Effectiveness Models in Alzheimer's Disease

Objectives: Decision-analytic models assessing the value of emerging Alzheimer's disease (AD) treatments are challenged by limited evidence on short-term trial outcomes and uncertainty in extrapolating long-term patient-relevant outcomes. To improve understanding and foster transparency and credibility in modeling methods, we cross-compared AD decision models in a hypothetical context of disease-m

Direct and indirect associations between dietary magnesium intake and breast cancer risk

This study aimed to explore the effect of dietary magnesium intake on breast cancer risk both directly and indirectly via its effect on inflammatory markers C-reactive protein (CRP) and interleukin-6 (IL-6). This case-control study recruited 1050 case patients and 1229 control subjects. Inflammatory marker levels of 322 cases and 322 controls, randomly selected, were measured using ELISA, and data

Transition metal transporting P-type ATPases : terminal metal-binding domains serve as sensors for autoinhibitory tails

Copper is an essential micronutrient and yet is highly toxic to cells at elevated concentrations. P1B-ATPase proteins are critical for this regulation, providing active extrusion across cellular membranes. One unique molecular adaptation of P1B-ATPases compared to other P-type ATPases is the presence of metal-binding domains (MBDs) at the cytosolic termini, which however are poorly characterized w

Carbohydrate, dietary glycaemic index and glycaemic load, and colorectal cancer risk: a case-control study in China

A carbohydrate-rich diet results in hyperglycaemia and hyperinsulinaemia; it may further induce the carcinogenesis of colorectal cancer. However, epidemiological evidence among Chinese population is quite limited. The aim of this study was to investigate total carbohydrate, non-fibre carbohydrate, total fibre, starch, dietary glycaemic index (GI) and glycaemic load (GL) in relation to colorectal c

Higher intakes of dietary vitamin D, calcium and dairy products are inversely associated with the risk of colorectal cancer: a case-control study in China

The effects of dietary vitamin D, Ca and dairy products intakes on colorectal cancer risk remain controversial. The present study investigated the association between these dietary intakes and the risk of colorectal cancer in Guangdong, China. From July 2010 to December 2018, 2380 patients with colorectal cancer and 2389 sex- and age-matched controls were recruited. Dietary intake data were collec

Association between flavonoids, flavonoid subclasses intake and breast cancer risk: a case-control study in China

Anti-tumor effect of dietary flavonoids has been sustained by laboratory experiments, but epidemiological studies with breast cancer risk remained inconsistent and insufficient. This study aimed to investigate the associations between total and subclasses of flavonoid and breast cancer risk among Chinese population. This case-control study recruited 1522 eligible breast cancer cases and 1547 frequ

Ranil Wickremesinghe : The Accidental Buddhist Diplomat

This chapter contextualizes and discusses the Buddhist approach taken by Ranil Wickremesinghe (born 1949), a prominent political figure who has served as Prime Minister of Sri Lanka on six occasions and who held the office of the ninth President until September 2024. It analyses Wickremesinghe’s political career and his ability to navigate the complex interplay between Sinhalese Buddhist ethno-rel

AI -- varken räddare eller förgörare

....men inte heller ett neutralt verktyg för offentlig förvaltning. Via en teknikhistorisk återblick diskuterar Stefan Larsson och Ellinor Blom Lussi aspekter av hur ny teknik, här med fokus på AI, påverkar individer, professioner och organisationer. Med denna introducerande artikel till temat digitalisering pekar de dels på några av de väldigt löftesrika tekniktrender som är kopplade till automat