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Dynamics-Based Optimal Motion Planning of Multiple Lane Changes using Segmentation

Avoidance maneuvers at normal driving speed or higher are demanding driving situations that force the vehicle to the limit of tire–road friction in critical situations. To study and develop control for these situations, dynamic optimization has been in growing use in research. One idea to handle such optimization computations effectively is to divide the total maneuver into a sequence of sub-maneu

Iam hiQ-a novel pair of accuracy indices for imputed genotypes

Background: Imputation of untyped markers is a standard tool in genome-wide association studies to close the gap between directly genotyped and other known DNA variants. However, high accuracy with which genotypes are imputed is fundamental. Several accuracy measures have been proposed and some are implemented in imputation software, unfortunately diversely across platforms. In the present paper,

Leaderless Management as the Solution to Struggles Over the Moral Center of Healthcare? : Ward Nurses’ Critique of Management as “Real Utopias” in the Public Sector

Through a historization of the Swedish public sector together with vignettes grounded in interviews, this paper questions managerialism in the public sector. The chapter argues for leaderless management as a shift of attention from managerialism toward worker control. The chapter explores what nurses identify as central areas of conflict shaping their work, and what forms of change they view as ne

Permeability, compressive strength and Proctor parameters of silts stabilised by Portland cement and ground granulated blast furnace slag (GGBFS)

The study investigates the effect of Portland cement and ground granulated blast furnace slag (GGBFS) added in changed proportions as stabilising agents on soil parameters: uniaxial compressive strength (UCS), Proctor compactness and permeability. The material included dredged clayey silts collected from the coasts of Timrå, Östrand. Soil samples were treated by different ratio of the stabilising

The HIBEAM/NNBAR Calorimeter Prototype

The HIBEAM/NNBAR experiment is a free-neutron search for n → sterile n and n → n¯ oscillations planned to be installed at the European Spallation Source under construction in Lund, Sweden. A key component in the experiment is the detector to identify n - n¯ annihilation events, which will produce on average four pions with a final state invariant mass of two nucleons, around 1.9 GeV. The beamline

Influence of an atomic resonance on the coherent control of the photoionization process

In coherent control schemes, pathways connecting an initial and a final state can be independently controlled by manipulating the complex amplitudes of their transition matrix elements. For paths characterized by the absorption of multiple photons, these quantities depend on the magnitude and phase between the intermediate steps, and are expected to be strongly affected by the presence of resonanc

Effects of diet-induced hypercholesterolemia and gold nanoparticles treatment on peripheral tissues

Cholesterol is a lipid molecule of great biological importance to animal cells. Dysregulation of cholesterol metabolism leads to raised blood total cholesterol levels, a clinical condition called hypercholesterolemia. Evidence has shown that hypercholesterolemia is associated with the development of liver and heart disease. One of the mechanisms underlying heart and liver alterations induced by hy

Towards Dense Point Correspondence with PatchMatch in Low-Resolution Sonar Images

Robust feature correspondences between 2D sonar imagery are important for perception tasks in the underwater domain such as 3D reconstruction but involve open challenges, in particular, low-resolution as well as the fact that object appearance is view-dependent. Although sonars in the MHz range would allow for higher resolution imagery, in this paper we focus on scenarios with a lower frequency kH

Diagnostic Accuracy of the Swedish Version of the Rowland Universal Dementia Assessment Scale (RUDAS-S) for Multicultural Cognitive Screening in Swedish Memory Clinics

Background: The number of people with a migration background and dementia is increasing in Europe. All patients with suspected dementia have the right to an appropriate cognitive assessment and correct diagnosis for optimal treatment and support. Rowland Universal Dementia Assessment Scale (RUDAS) cognitive screening instrument is less affected by language, culture, and educational background, and

Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

The discovery of genetic loci associated with complex diseases has outpaced the elucidation of mechanisms of disease pathogenesis. Here we conducted a genome-wide association study (GWAS) for coronary artery disease (CAD) comprising 181,522 cases among 1,165,690 participants of predominantly European ancestry. We detected 241 associations, including 30 new loci. Cross-ancestry meta-analysis with a

"Giving Voice and Ending Silence" : John-Paul Himka, Ukrainian Nationalists and the Holocaust: OUN and UPA's Participation in the Destruction of Ukrainian Jewry, 1941-1944. Stuttgart: ibidem-Verlag, 2021, 446 pp.

John-Paul Himka’s new book, Ukrainian Nationalists and the Holocaust: OUN and UPA’s Participation in the Destruction of Ukrainian Jewry, 1941-1944, represents a milestone in research on the complicity of the OUN-UPA in the Holocaust. Based on decades worth of research in dozens of archives around the world, Himka makes a well-documented and indisputable case for Ukrainian nationalist involvement i

AN EXPERIMENTAL STUDY ON HEAT TRANSFER PERFORMANCE OF JET IMPINGEMENT ARRAYS

Jet impingement cooling is an effective way for thermal management in electronics, prevailed over many other single heat transfer modes. In general, jet arrays are better than a single jet, enhancing jet cooling performance. However, the performance of jet arrays is strongly dependent on the jet configurations, e.g., adjacent jet interval and hole-to-surface distance. Thus, in this study, jet impi

Women’s experience of the decision-making process for home-based postnatal midwifery care when discharged early from hospital : A Swedish interview study

INTRODUCTION Women and their families are often excluded from reproductive decisionmaking processes in postnatal care, and do not know which choices they have. Shared decision-making is a critical but challenging component of maternity care quality. The aim was to explore women's experience of the decision-making process about early return from hospital with home-based postnatal midwifery care. ME

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John-Paul Himka’s new book, Ukrainian Nationalists and the Holocaust: OUN and UPA’s Participation in the Destruction of Ukrainian Jewry, 1941-1944, represents a milestone in research on the complicity of the OUN-UPA in the Holocaust. Based on decades worth of research in dozens of archives around the world, Himka makes a well-documented and indisputable case for Ukrainian nationalist involvement i

Ten new insights in climate science 2022

We summarize what we assess as the past year's most important findings within climate change research: limits to adaptation, vulnerability hotspots, new threats coming from the climate-health nexus, climate (im)mobility and security, sustainable practices for land use and finance, losses and damages, inclusive societal climate decisions, and ways to overcome structural barriers to accelerate mitig

The relevance of rich club regions for functional outcome post-stroke is enhanced in women

This study aimed to investigate the influence of stroke lesions in predefined highly interconnected (rich-club) brain regions on functional outcome post-stroke, determine their spatial specificity and explore the effects of biological sex on their relevance. We analyzed MRI data recorded at index stroke and ~3-months modified Rankin Scale (mRS) data from patients with acute ischemic stroke enrolle

Genetic variation of the blood coagulation regulator tissue factor pathway inhibitor and venous thromboembolism among middle-aged and older adults: A population-based cohort study

Background: Tissue factor is the main initiator of blood coagulation, and tissue factor pathway inhibitor (TFPI) is the primary inhibitor of the initiation of blood coagulation. The genetic variation of TFPI and the relation to venous thromboembolism (VTE), that is, venous thrombosis and pulmonary embolism, remains to be clarified. This exome sequencing study aimed to determine the molecular epide