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”Offentliga sektorn måste utvecklas nära medborgarna”
”Störst av allt är ärligheten.”
”Hitta armlängds avstånd i kommunpolitiken.”
Ett mänskligare arbetsliv : Samlade krönikor för samtal om framtiden
Idag präglas många organisationer, inte minst i offentlig sektor, av ett starkt fokuspå regelverk, juridik, tekniska system och ekonomiska resultat. Utrymmet fördet mänskliga är begränsat. I denna bok samlar Louise Bringselius 22 krönikorpå temat människa, arbetsliv och samhälle och målar upp en vision om störreutrymme för det mänskliga. Boken kan användas som underlag för samtal omframtiden eller
Att leda med tillit får inte bara bli blomsterspråk
Patientens tillit börjar med ledningens tillit till professionen
Self-reactive T cells induce and perpetuate chronic relapsing arthritis
Background: CD4+ T cells play a central role during the early stages of rheumatoid arthritis (RA), but to which extent they are required for the perpetuation of the disease is still not fully understood. The aim of the current study was to obtain conclusive evidence that T cells drive chronic relapsing arthritis. Methods: We used the rat pristane-induced arthritis model, which accurately portrays
Perfusion weighted MR imaging may differentiate primary CNS-lymphoma from other homogeneously enhancing brain tumors.
Primary central nervous system lymphoma (PCNSL), glioblastoma multiforme (GBM) and metastases may be difficult to differentiate based on conventional imaging alone. The aim of this study was to investigate the value of perfusion weighted imaging (PWI) in differentiating homogeneously enhancing PCNSL from homogeneously enhancing GBM and metastases. Seven consecutive patients presenting with homogen
Imaging biomarkers in neurodegeneration : Current and future practices
There is an increasing role for biological markers (biomarkers) in the understanding and diagnosis of neurodegenerative disorders. The application of imaging biomarkers specifically for the in vivo investigation of neurodegenerative disorders has increased substantially over the past decades and continues to provide further benefits both to the diagnosis and understanding of these diseases. This r
Battle, Journey, Imprisonment and Burden : Patterns of metaphor use in blogs about living with advanced cancer
Background: The significance of metaphors for the experience of cancer has been the topic of extensive previous research, with "Battle" and "Journey" metaphors standing out as key. Adaptation to the patient's use of metaphor is generally believed to be an important aspect of person-centered care, especially in palliative care. The aim of this study was to investigate the use of metaphors in blogs
Socioeconomic status and survival after stroke - Using mediation and sensitivity analyses to assess the effect of stroke severity and unmeasured confounding
Background: Although it has been established that low socioeconomic status is linked to increased risk of death after stroke, the mechanisms behind this link are still unclear. In this study we aim to shed light on the relationship between income level and survival after stroke by investigating the extent to which differences in stroke severity account for differences in survival. Methods: The stu
Broadening risk profile in familial colorectal cancer type X; Increased risk for five cancer types in the national Danish cohort
Background: Familial colorectal cancer type X (FCCTX) is a phenotypically defined subset of hereditary colorectal cancer with unknown and potentially heterogeneous genetic aetiology. FCCTX has been characterized as a colorectal cancer-specific syndrome, which we herein challenge by estimating the risk for extra-colorectal cancer in the Danish FCCTX cohort. Methods: Through the national hereditary
Proteolysis of Iron Oxide-Associated Bovine Serum Albumin
Proteins are a substantial nitrogen source in soils provided that they can be hydrolyzed into bioavailable small peptides or amino acids. However, the strong associations between proteins and soil minerals restrict such proteolytic reactions. This study focused on how an extracellular fungal protease (Rhizopus sp.) hydrolyzed iron oxide-associated bovine serum albumin (BSA) and the factors that af
Non-reversible heat-induced gelation of a biocompatible Fmoc-hexapeptide in water
Hydrogel materials which respond to changes in temperature are widely applicable for injectable drug delivery or tissue engineering applications. Here, we report the unsual heat-induced gelation behaviour of a low molecular weight gelator based on an Fmoc-hexapeptide, Fmoc-GFFRGD. We show that Fmoc-GFFRGD forms kinetically stable fibres when mixed with divalent cations (e.g. Ca2+). Gelation of the
Theoretical framework focusing on learning in polycentric settings
This deliverable provides the theoretical underpinning of the NEWCOMERS project, including the key concepts and definitions as well as the formulation of research propositions in order to enhance the project’s coherence. To this end, it develops a novel theoretical framework based on polycentric governance theory, combined with elements from socio-technical systems theory, social innovationtheory,This deliverable provides the theoretical underpinning of the NEWCOMERS project, including the key concepts and definitions as well as the formulation of research propositions in order to enhance the project’s coherence. To this end, it develops a novel theoretical framework based on polycentric governance theory, combined with elements from socio-technical systems theory, social innovationtheory,
Risk of hypertension into adulthood in persons born prematurely : A national cohort study
Aims: Preterm birth has been associated with elevated blood pressure early in life; however, hypertension risks from childhood into adulthood remain unclear. We conducted a large population-based study to examine gestational age at birth in relation to hypertension risks from childhood into adulthood. Methods and results: A national cohort study was conducted of all 4 193 069 singleton live births
Spontaneous Formation of Cushioned Model Membranes Promoted by an Intrinsically Disordered Protein
In this article, it is shown that by exposing commonly used lipids for biomembrane mimicking studies, to a solution containing the histidine-rich intrinsically disordered protein histatin 5, a protein cushion spontaneously forms underneath the bilayer. The underlying mechanism is attributed to have an electrostatic origin, and it is hypothesized that the observed behavior is due to proton charge f
Ambipolar transport in narrow bandgap semiconductor InSb nanowires
We report on a transport measurement study of top-gated field effect transistors made out of InSb nanowires grown by chemical vapor deposition. The transistors exhibit ambipolar transport characteristics revealed by three distinguished gate-voltage regions: In the middle region where the Fermi level resides within the bandgap, the electrical resistance shows an exponential dependence on temperatur