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Background and hypothesis Knowledge regarding access to first kidney transplantation (KT) and subsequent KT in patients commencing kidney replacement therapy (KRT) in childhood is limited. Methods Using European Renal Association (ERA) Registry data, we investigated European patients who started KRT below 20 years of age between 1978 and 2019. Access and determinants to first, second, and third KT

Over the past decade, organic–inorganic hybrid perovskites have revolutionized next-generation semiconductors, driving unprecedented advancements in cost-effective optoelectronics. While lead-based perovskite semiconductors exhibit exceptional optoelectronic properties, their inherent toxicity and vulnerability to environmental degradation remain significant barriers to widespread commercializ

Climate change is one of the major drivers of biodiversity loss. Among vertebrates, amphibians are one of the more sensitive groups to climate change due to their unique ecology, habitat requirements, narrow thermal tolerance and relatively limited dispersal abilities. We projected the influence of climate change on an endemic toad, Malabar Tree Toad (Pedostibes tuberculosus; hereafter MTT) from t

Vitamin A deficiency (VAD) remains a severe health issue in sub-Saharan Africa, causing blindness, illness, and child mortality. In Mozambique, about 69% of children under five are affected, highlighting the short-term impact and donor dependence of supplementation programs. Mangoes (Mangifera indica L.), rich in provitamin A carotenoids, offer a sustainable, food-based strategy to reduce VAD, but

Micropollutants in wastewater can persist through conventional treatment, threatening ecosystems and human health through toxicity, bioaccumulation, and disruption of biological processes. Limited monitoring, due to cost and methodological challenges, allows these compounds to go undetected, potentially leading to long-term, irreversible impacts. To address this, modern wastewater treatment plants

Visual ecology, the study of how animals acquire and respond to visual information in nature, has grown rapidly over the past few decades. Research in this field has transformed our understanding of fundamental processes, such as the neurobiological basis of behavior and the diversification of species through sensory drive. The recent growth in the field has been accompanied by leaps in our unders

One of the key skills of any scientist is noticing what’s going on. Both in the experiment one’s performing and in one’s data: is there something interesting, reason to doubt one’s data or suspect that one’s theoretical description is insufficient? Many experiments developed for undergraduate teaching still focus on quantitative evaluation. Here we take a different approach where careful observati

Halide perovskite solar cells (PSCs) have emerged as a transformative photovoltaic technology, achieving unprecedented power conversion efficiencies. However, the development of electron-transport materials (ETMs), particularly organic ETMs, has significantly trailed behind the rapid progress in hole-transport materials (HTMs). Among the organic ETMs, naphthalene diimide (NDI)-based systems stand

Rationale: There is no consensus on criteria to include in an asthma remission definition in real life. Factors associated with achieving remission after biologic initiation remain poorly understood. Objectives: To quantify the proportion of adults with severe asthma achieving multidomain-defined remission after biologic initiation and identify prebiologic characteristics associated with achieving

Thermal runaway in lithium-ion battery cells poses significant safety risks due to rapid heat generation and potential thermal propagation within a battery system. This study investigates the total heat released and the fraction of energy contained in gas and particles ejected during thermal runaway using a purpose-built calorimeter setup. The results show that the fraction of ejected heat is sign

Until now, computationally designed enzymes exhibited low catalytic rates1, 2, 3, 4–5 and required intensive experimental optimization to reach activity levels observed in comparable natural enzymes5, 6, 7, 8–9. These results exposed limitations in design methodology and suggested critical gaps in our understanding of the fundamentals of biocatalysis10,11. We present a fully computational workflow

Byggnadsblocken som bär framtidens Tanzania I Tanzania och dess grannländer är byggnadsmaterialet sandcrete grunden till mycket av det som byggs när befolkningen ökar kraftigt. Det är billigt, går att tillverka lokalt och kräver inte mer än händer och formar. Ändå rymmer detta enkla block ett större problem. Cementet som behövs är dyrt och klimattungt och bristande kontroller i produktion gör attThis study investigates the potential for sustainable building practices in the sub-Saharan regional context, using small- and medium-scale sandcrete block production in Tanzania as a case study. The research combines a literature review on sustainability challenges in the region with insights from two semi-structured interviews. One with a local practitioner who regularly collaborates with small-

Background: Islet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and presentation. We hypothesized that autoantibodies can identify heterogeneity before, at, and after T1D diagnosis, and in response to disease-modifying therapies. Methods: We systematically reviewed PubMed and EMBASE databases (6/14/2022) assessing 10

This work is devoted to the development and comprehensive validation of a new interatomic potential for bcc and hcp refractory alloys based on the Wsingle bondMosingle bondNbsingle bondTasingle bondZrsingle bondTi system. The presented model allows the simulation of various structural transformations, as well as the behavior of crystal defects in several of the phases observed in this system. The

Although the economic impact of standards has been investigated for over two decades, the effect of the entire quality infrastructure, encompassing standards, conformity assessment, accreditation, metrology, and market surveillance, has been examined primarily through specific case studies. The objective of this analysis is to conduct an econometric analysis to assess the economic value of quality

Being one of the largest industries, the agricultural sector is central to achieving EU and UN sustainability goals. However, the role of sustainable business model innovation (SBMI) in low-tech sectors, such as agriculture, remains empirically underexplored, as existing research has largely focused on high-tech industries and large firms. The paper addresses this gap by examining how SBMI can sup

This study examines the relationship between income-related health inequality (IRHI) and macroeconomic conditions. We complement an income group-based analysis of the impact of macroeconomic conditions on mortality by incorporating an analysis of the concentration index as a comprehensive measure of overall IRHI. Using a recentered influence function regression approach, we estimate the impact of

This dataset reports on the Fourier-transform infrared (FTIR) spectroscopic analysis of a primary amine and some aldehydes along their corresponding Schiff bases. The dataset presented in this work consists of spectral FTIR data acquired in the 80–6000 cm⁻¹ range, along with the corresponding relative IR intensities of the samples. The primary amine and aldehydes were of high purity and were used

The Carina Nebula is an active star-forming region with several open clusters rich in massive OB stars, thus making it an optimal target for studying stellar properties such as rotation for large samples of these early-type stars. We studied a sample of early-type stars probable members of the eight open clusters in the Carina Complex. The observational data consist of high-resolution spectra from

The Grobe-Eberly doublet phenomenon occurs in photoelectron distributions when a field dresses the remaining ion. Its manifestation is due to entanglement between a free electron and a hybrid state of light and matter. Direct detection of such entanglement is however not possible by coincidence schemes due to the dressing mechanism having an inconspicuous phase-correlation effect on the ion. Here,