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Design of antibody microarrays for global profiling of membrane proteins and soluble proteins

Antibody-based microarrays have emerged as an established proteomic technology allowing multiplexed and sensitive profiling of complex proteomes, in a high-throughput and miniaturized manner. Recently, numerous applicative efforts have been pursued generating disease-associated protein signatures that now could be further explored for improved disease diagnostics, prognostics and classification.

Experimental characterization of the body-coupled communications channel

Body-coupled communications (BCC), in which the human body is used as a communications channel, has been shown to be a promising solution for wireless body-area networks (WBANs). For successful deployment of these BCC-based WBANs, it is necessary to develop a clear understanding of the channel behavior. Therefore, this paper presents the key characteristics of the capacitively-coupled on-body chan

How we focus attention in picture viewing, picture description, and during mental imagery

We cannot directly uncover the contents of our mind but we can come closer to cognitive processes via overt manifestations. I am interested in how speakers perceive, conceptualise and spontaneously describe complex pictures on higher levels of discourse and I use eye tracking methodology along with verbal protocols and a multimodal scoring method to study these mental processes. In the studies on

Metabolic Engineering of the Pentose Phosphate Pathway of Xylose Fermenting Saccharomyces cerevisiae

The aim of the work presented in this thesis is the improvement of xylose fermentation performance of recombinant Saccharomyces cerevisiae strains expressing XYL1 and XYL2 from Pichia stipitis, encoding xylose reductase (XR) and xylitol dehydrogenase (XDH). A recombinant strain of S. cerevisiae, fermenting both xylose and glucose to ethanol could decrease the production cost of ethanol from ligno-

Experimental Bladder Reconstruction

Reduced urinary bladder capacity is a clinically significant problem. The surgical methods that have been available to treat this, such as urinary diversion or surgically augmenting the bladder by incorporation of intestinal segments, all have serious drawbacks. There is a need to understand how the smooth muscle of the intestine and bladder can interact when brought into close contact surgically,

Wavelet analysis of in-cylinder LDV velocity measurements

The Discrete Wavelet Transform (DWT) is a new way to analyze gas flow measurements in engine cylinders. The DWT technique differs significantly from the Fast Fourier Transform (FFT) in that with the former, the analysis of information can be done in both the time domain and frequency domain. The basic theory of wavelets is presented and the use of DWT is demonstrated on information derived from la

Biofuels for Transport in the Asia-Pacific Region

The purpose is to provide a brief overview of activities related to biofuels for transport in the Asia-Pacific Region, which covers a diverse range of countries and economies. The focus is on the Asia-Pacific Economic Cooperation (APEC),which is the premier forum for facilitating economic growth, cooperation, trade, and investment in the Asia-Pacific Region. APEC provides a forum for cooperation o

DNA repair and the p53 pathway in ischemic and traumatic brain injury

Popular Abstract in Swedish BAKGRUND Hjärnskador till följd av otillräckligt blodflöde eller skallskador drabbar varje år ett stort antal människor i vårt land. Otillräckligt blodflöde till hjärnan (cerebral ischemi) uppträder vid en rad kliniska tillstånd, exempelvis slaganfall (stroke), hjärtstillestånd och gravt sänkt blodtryck. Hjärnskador till följd av våld mot huvudet (traumatiska hjärnskadIschemic and traumatic brain damage are major causes of disability and death. While much effort has been spent to develop pharmacological treatments for these conditions, no neuroprotective drugs are in clinical use. Neuronal death following ischemia and trauma occurs in selected cell populations of the brain at various time points after the insult. It is believed that death of neurons are in part

Pilots and ground officers investigated by process tests of creativity, extraversion, and stress control

In an exploratory investigation of personality patterns, Swedish air force pilots (n = 22) and ground officers (n = 14) were tested with the Creative Functioning Test, the Serial Color Word test, and the Spiral After-Effect Technique. The participants also answered open questions about their work and about creativity related items. Achievement ratings were made by their superior officers. An initi

Comparison of heat transfer from baby and adult manikins

Data from 3 whole body manikins, 2 babies and an adult, were used in the study. All the manikins used the same computer program and similar measuring and control units. No special measurements were made for baby and adult manikin comparison, but available data from earlier measurements was used. The conditions involved air layer insulation measurements (AL), laying on back on an insulating surface