Exploring Breast Cancer Associated Fibroblast Subpopulations By Using Single-Cell RNA Sequencing
In the tumor microenvironment, Cancer-Associated Fibroblasts (CAFs) are the most represented cell type. Research has shown increasingly the key role of CAFs in cancer growth and evolution, creating the need to identify more clearly and further characterize the CAF population. In this study, looking at single cell RNA sequencing of 768 CAF transcriptomes, we define transcriptionally distinct subpop