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Evaluation of image reconstruction methods for 123I-MIBG-SPECT: a rank-order study.

Background: There is an opportunity to improve the image quality and lesion detectability in single photon emission computed tomography (SPECT) by choosing an appropriate reconstruction method and optimal parameters for the reconstruction. Purpose: To optimize the use of the Flash 3D reconstruction algorithm in terms of equivalent iteration (EI) number (number of subsets times the number of itera

Family history of venous thromboembolism as a risk factor and genetic research tool.

Familial clustering of venous thromboembolism (VTE) was described as far back as 1905 by Briggs. Although Egeberg discovered inherited deficiency of antithrombin in 1965, it was not until Dahlbäck discovered resistance to activated protein C in 1993 that it became clear that genetic factors are common risk factors of VTE. Several genes have been linked to familial aggregation of VTE and genome-wid

A Measurement Framework for Team Level Assessment of Innovation Capability in Early Requirements Engineering

When developing software-intensive products for a market-place it is important for a development organisation to create innovative features for coming releases in order to achieve advantage over competitors. This paper focuses on assessment of innovation capability at team level in relation to the requirements engineering that is taking place before the actual product development projects are deci

EndoS Reduces the Pathogenicity of Anti-mCOL7 IgG through Reduced Binding of Immune Complexes to Neutrophils.

Endo-β-N-acetylglucosaminidase (EndoS) has been shown to act as a potent pathogen-derived immunomodulatory molecule in autoimmune diseases. Here we investigated how EndoS treatment reduces the pathogenicity of rabbit anti-mCOL7 IgG using different experimental models of epidermolysis bullosa acquisita (EBA). Our results show that the EndoS treatment does not interfere with the binding of the antib

Multidimensional Treatment Foster Care (MTFC): Results from an independent replication

This study examines 24-months post-baseline outcomes for thirty-five Swedish antisocial youths who received either treatment in multidimensional treatment foster care (MTFC) or treatment as usual (TAU). MTFC is a community-based treatment programme that has been successful in treating chronic juvenile offenders in the USA. This study is the first randomized control study outside the USA. The youth

Prognostic impact of polymorphisms in the MYBL2 interacting genes in breast cancer

MYBL2 is a transcription factor, which regulates the expression of genes involved in cancer progression. In this study, we investigated whether putative functional variants in genes regulating MYBL2 (E2F1, E2F3 and E2F4) or in genes, which are regulated by MYBL2 (BCL2, BIRC5, COL1A1, COL1A2, COL5A2, ERBB2, CLU, LIN9 and TOP2A) affect breast cancer (BC) susceptibility and clinical outcome. Twenty-e

Electronic structure changes in cobalt phthalocyanine due to nanotube encapsulation probed using resonant inelastic X-ray scattering

The electronic structure of cobalt phthalocyanine (CoPc) changes upon encapsulation inside multi-walled carbon nanotubes (CoPc@MWNT), as detected in this research using Co-K-edge X-ray absorption near-edge structure spectroscopy (XANES) and Co-K alpha(1) resonant inelastic X-ray scattering (RIXS). The CoPc molecules are no longer planar once inside the nanotubes, and the molecular symmetry is foun

Självets garderobiär : Självreflexiva genuslekar och queer socialpsykologi

Popular Abstract in Swedish Det övergripande syftet med föreliggande studie är tudelat. För det första syftar den till att på teoretisk väg etablera en dialog mellan queerteoretisk och socialpsykologisk teoribildning om aktörer och aktörsskap med utgångspunkt i en kritisk läsning av Judith Butler och George Herbert Mead. För det andra syftar den till att på empirisk väg utveckla och fördjupa dennaIn her widely quoted and criticised Gender Trouble, Judith Butler elaborates the idea that gender needs to be understood as performative – a certain kind of “doing” within the regulative realm of a hegemonic heterosexuality that is assumed to govern intelligible bodily configurations. Drawing mainly on psychoanalytical and Foucaultian arguments, Butler dwells upon questions concerning power and su

Contact allergy to fragrances with a focus on oak moss absolute

The exposure to fragrances is widespread and contact allergy to fragrance substances affects 1–4% of the general population. Many fragrance substances are volatile and it can therefore be suspected that they may evaporate from petrolatum patch test preparations applied in test chambers. In the first two papers included in this thesis the aims were to i) to investigate the stability of fragrance pr

Does job strain mediate the effect of Socio-economic Group on smoking behaviour? The impact of different health policies in Denmark and Sweden

Aims: The aim was to compare the impact of socioeconomic groups (SEG) on the risk of being a daily smoker or quitter, and to investigate whether the potentially mediating effect of psychosocial working conditions was similar in the Danish and the Swedish populations. Methods: The study populations consisted of 10,049 employed participants, aged 18-64 years, 51% women, randomly selected from the ge

Cerebrospinal fluid levels of complement proteins C3, C4 and CR1 in Alzheimer's disease

Alzheimer's disease (AD) is strongly associated with loss of synapses. The complement system has been shown to be involved in synaptic elimination. Several studies point to an association between AD and the complement system. The purpose of this study was to examine the association of cerebrospinal fluid (CSF) levels of complement components 3 and 4 (C3 and C4, respectively), and complement recept

Water Crisis in The Middle East: An Opportunity for New Forms of Water Governance and Peace

The Middle East, home to 6.3 percent of the world’s population and containing only 1.4 percent of the world’s renewable fresh water, is experiencing an increasing water scarcity crisis.1 The UN presented an alarming report during the last World Water Forum in March 2009 painting a bleak picture of increasing demand and diminishing water supplies.2 Scientifically, the Middle East ran out of water i

A Nanoscale Standard for the Seebeck Coefficient

The Seebeck coefficient, a key parameter describing a material's thermoelectric performance, is generally difficult to measure, and no intrinsic calibration standard exists. Quantum dots and single electron tunneling devices with sharp transmission resonances spaced by many kT have a material-independent Seebeck coefficient that depends only on the electronic charge and the average device temperat

Livscykelanalys av svenska biodrivmedel

Syftet med detta projekt är att göra uppdaterade och utvecklade livscykelanalyser för biodrivmedel som är aktuella i Sverige idag. Fokus ligger på att göra så transparenta och relevanta jämförelser som möjligt och att lyfta fram de steg i livscykeln som signifikant påverkar respektive biodrivmedels miljöprestanda. I studien görs känslighetsanalyser som visar effekterna av t ex framtida förändrade

Motor ability in children treated for idiopathic clubfoot. A controlled pilot study

Background: To study motor ability at seven years of age in children treated for idiopathic clubfoot and its relation to clubfoot laterality, foot status and the amount of surgery performed. Methods: Twenty children (mean age 7.5 years, SD 3.2 months) from a consecutive birth cohort from our hospital catchments area (300.000 inhabitants from southern Sweden) were assessed with the Movement Assessm