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Hypothermia in cardiogenic shock reduces systemic t-PA release.

Therapeutic hypothermia has been found to improve hemodynamic and metabolic parameters in cardiogenic shock. Tissue plasminogen activator (t-PA) is a pro-thrombolytic enzyme, which also possesses pro-inflammatory properties. Interleukin 6 (IL-6) and tumour necrosis factor alpha (TNF-α) are pro-inflammatory cytokines; interleukin 10 (IL-10) and transforming growth factor beta 1 (TGF-β1) are anti-in

Levosimendan in early experimental sepsis: effects on the heart and hepatosplanchnic circulation

Popular Abstract in Swedish Blodförgiftningen (sepsis) kan ge upphov till akut hjärtsvikt, vilken på cellulär nivå karakteriseras av minskad känslighet för kalciumjonen och de vanliga hjärtförstärkande medicinerna (inotropa farmaka). Avhandlingen handlar om tidig behandling av sepsis-associerad hjärtsvikt med den kalciumsensitiseraren levosimendan, ett nytt läkemedel som höjer hjärtats kontraktionSepsis-related cardiovascular dysfunction associated with fluid-unresponsive tissue hypoperfusion might require inotropic treatment. This cardiovascular dysfunction seems to involve calcium desensitization and adrenergic unresponsiveness. We investigated the effects of clinically relevant plasma concentrations of the calcium sensitizer levosimendan during the first 6 h of endotoxemia in a model of

Particle Filtering and Optimal Control for Vehicles and Robots

This thesis covers areas within estimation and optimal control of vehicles, in particular four-wheeled vehicles. One topic is how to handle delayed and out-of-sequence measurements (OOSMs) in tracking systems. The motivation for this is that with technological development and exploitation of more sensors in tracking systems, OOSMs gain more significance in various applications. The thesis derives

Non-host volatile blend optimization for forest protection against the European Spruce Bark Beetle, Ips typographus

Conifer feeding bark beetles (Coleoptera, Curculionidae, Scolytinae) pose a serious economic threat to forest production. Volatiles released by non-host angiosperm plants (so called non-host volatiles, NHV) have been shown to reduce the risk of attack by many bark beetle species, including the European spruce bark beetle, Ips typographus. However, the most active blend for I. typographus, containi

Soldiers and Citizens: The concept of citizenship and the Anjala Covenant, 1788-1790

This article discusses the relationship between 'citizenship' and military duty during the late 18th century. This is illustrated by the legal conflict that erupted between the members of the Anjala Covenant and the Board of War in 1788. In a study of the records from the following court martial, the trial is viewed as a political discussion concerning the definition of the concept of the 'citizen

The European Grassland Butterfly Indicator: 1990–2011

This report presents the European Grassland Butterfly Indicator, based on national Butterfly Monitoring Schemes (BMS) in 19 countries across Europe, most of them in the European Union. The indicator shows that since 1990 till 2011 butterfly populations have declined by almost 50 %, indicating a dramatic loss of grassland biodiversity. This also means the situation has not improved since the first

Pancreaticojejunostomy: A valid operation in chronic pancreatitis?

Objective. Patients with chronic pancreatitis and intractable pain may be candidates for surgical intervention and various types of surgery have been described over time. The objective of this study was to describe long-term outcome following pancreaticojejunostomy in patients with chronic pancreatitis. Material and methods. Thirty-two patients with chronic pancreatitis underwent lateral pancreati

Vasovagal Syncope Related to Emotional Stress Predicts Coronary Events in Later Life

Background: The aim of the study was to assess whether history of vasovagal syncope (VVS) mediated by emotional (emotional VVS) or orthostatic stress (orthostatic VVS) is associated with an increased risk of cardiovascular (CV) events in later life. Methods: Retrospective analysis based on medical records of the consecutive 3,288 cardiologic outpatients (mean age, 61 +/- 12 years; 43% men). Result

Morphology of SBA-15-directed by association processes and surface energies.

We present a model that explains the morphology of mesoporous SBA-15 particles based on the relative surface energies of the defining faces. We also describe how the formation process influences the morphology and hence the surface energies. The model is compared to experimental observations, made primarily with scanning and transmission electron microscopy. Some materials were also examined in mo

Teamarbete på operationssal, organisationsdesign och patientsäkerhet

Teamarbete är vanligt inom hälso- och sjukvården. I mitt avhandlingsarbete har jag studerat teamarbete på operationssal med fokus på hur det praktiska arbetet faktiskt går till. Avhandlingens delstudier berör sådant som den praktiska användningen av formella rutiner (WHOs checklista för säker kirurgi), ledarskap på operationssal, olika professioners syn på det gemensamma arbetet, testning av en me

Does exogenous carbon extend the realized niche of canopy lichens? Evidence from sub-boreal forests in British Columbia

Foliose lichens with cyanobacterial bionts (bipartite and tripartite) form a distinct assemblage of epiphytes strongly associated with humid microclimatic conditions in inland British Columbia. Previous research showed that these cyano- and cephalolichen communities are disproportionately abundant and species-rich on conifer saplings beneath Populus compared to beneath other tree species. More rev

Measurement of tau polarization in W -> tau nu decays with the ATLAS detector in pp collisions at root s=7 TeV

In this paper, a measurement of tau polarization in W -> tau nu decays is presented. It is measured from the energies of the decay products in hadronic tau decays with a single final state charged particle. The data, corresponding to an integrated luminosity of 24 pb(-1), were collected by the ATLAS experiment at the Large Hadron Collider in 2010. The measured value of the tau polarization is P-ta

A parametric Analysis of the Undeformed Chip Geometry in Gear Hobbing

Hobbing is a common manufacturing method when producing helical, involute gears. In order to increase tool life and surface finish, an accurate method to determine chip geometry is needed. Although this accurateness may involve numeric solutions, the geometric description must, as far as possible, be analytic and give a description of the continuously changing chip geometry. In this report, the c

Sonogashira coupling reaction over supported gold nanoparticles: Influence of support and catalyst synthesis route

This study investigates the impact of supports and synthesis routes on the performance of supported gold nanoparticles in the Sonogashira coupling reaction. The catalysts were synthesized by deposition-precipitation (DP) and incipient wetness impregnation (IMP), employing carriers of different nature (redox: CeO2, TiO2, and non-redox: Al2O3) and were characterized by various physical techniques su

Assignment of the L2,3VV normal Auger decay spectrum of Cl-2 by ab initio calculations

Auger decay processes of the Cl 2p ionized states have been studied in Cl-2 by means of high- resolution electron spectroscopy and ab initio calculations. This led to reassignment of the normal L2,3VV Auger decay spectrum of Cl2. The reliability of this assignment is strongly supported by an independent measurement of the L2; 3VV Auger electron spectrum of Cl2 which has been obtained after selecti

Effects of autism spectrum disorders on outcome in teenage-onset anorexia nervosa evaluated by the Morgan-Russell outcome assessment schedule: a controlled community-based study

Background: The purpose of the study was to evaluate time trends and effects of co-existing autism spectrum disorders (ASD) on outcome in an ongoing long-term follow-up study of anorexia nervosa (AN). Methods: The Morgan-Russell Outcome Assessment Schedule (MROAS) was used at 6-, 10- and 18-year follow-up of a representative sample of 51 individuals with teenage-onset AN and a matched group of 51

On the concentration-induced growth of nonionic wormlike micelles.

We present a comprehensive study of the concentration-induced growth of nonionic wormlike micelles in dilute solutions, below the overlap concentration, where we combine static and dynamic light scattering and NMR self-diffusion. The data are analyzed in detail in terms of the number-averaged contour length, assuming an exponential size distribution, as predicted by theory, and that the micellar f

Evidence from Formosan for a unified theory of adverb ordering

This paper presents evidence from the Austronesian languages of Taiwan (Formosan languages) bearing on the ongoing debate between followers of Cinque (1999: Adverbs and functional heads) and Ernst (2002: The syntax of adjuncts): are adverbs adjoined to the clause, with semantically determined ordering, or are they located in functional projections in the backbone of the clause, with the ordering d