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Microbial control of soil organic matter mineralization responses to labile carbon in subarctic climate change treatments

Half the global soil carbon (C) is held in high-latitude systems. Climate change will expose these to warming and a shift towards plant communities with more labile C input. Labile C can also increase the rate of loss of native soil organic matter (SOM); a phenomenon termed ‘priming’. We investigated how warming (+1.1 °C over ambient using open top chambers) and litter addition (90 g m−2 yr−1) tre

Event-Shape Engineering and Jet Quenching

Event-Shape Engineering (ESE) is a tool that enables some control of the initial geometry in heavy-ion collisions in a similar way as the centrality enables some control of the number of participants. Utilizing ESE, the path length in and out-of plane can be varied while keeping the medium properties (centrality) fixed. In this proceeding it is argued that this provides additional experimental inf

Quantifying Interparticle Forces and Heterogeneity in 3D Granular Materials

Interparticle forces in granular materials are intimately linked to mechanical properties and are known to self-organize into heterogeneous structures, or force chains, under external load. Despite progress in understanding the statistics and spatial distribution of interparticle forces in recent decades, a systematic method for measuring forces in opaque, three-dimensional (3D), frictional, stiff

Who instigates university–industry collaborations? University scientists versus firm employees

While evidence on the causes and effects of university–industry interaction is abundant, little is known about how, and particularly by whom, such interaction is instigated in the first place and subsequently managed. In this paper, we investigate which mode of collaboration (joint research, contract research, consulting, in-licensing, or informal contacts) is more likely to be initiated and manag

The Different Roles of Aggrecan Interaction Domains

The aggregating proteoglycans of the lectican family are important components of extracellular matrices. Aggrecan is the most well studied of these and is central to cartilage biomechanical properties and skeletal development. Key to its biological function is the fixed charge of the many glycosaminoglycan chains, that provide the basis for the viscoelastic properties necessary for load distributi

miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts

Uncontrolled cell proliferation and cytoskeletal remodeling are responsible for tumor development and ultimately metastasis. A number of studies have implicated microRNAs in the regulation of cancer cell invasion and migration. Here, we show that miR-23b regulates focal adhesion, cell spreading, cell-cell junctions and the formation of lamellipodia in breast cancer (BC), implicating a central role

Clathrin and LRP-1-independent constitutive endocytosis and recycling of uPAR

BACKGROUND: The urokinase receptor (uPAR/CD87) is highly expressed in malignant tumours. uPAR, as a GPI anchored protein, is preferentially located at the cell surface, where it interacts with its ligands urokinase (uPA) and the extracellular matrix protein vitronectin, thus promoting plasmin generation, cell-matrix interactions and intracellular signalling events. Interaction with a complex forme

Monomer dimer dynamics and distribution of GPI-anchored uPAR are determined by cell surface protein assemblies

To search for functional links between glycosylphosphatidylinositol (GPI) protein monomer-oligomer exchange and membrane dynamics and confinement, we studied urokinase plasminogen activator (uPA) receptor (uPAR), a GPI receptor involved in the regulation of cell adhesion, migration, and proliferation. Using a functionally active fluorescent protein-uPAR in live cells, we analyzed the effect that e

Close to Nature

What does it mean to be close to nature? This question is examined in this video work based on 9 short clips. The first clip of a woody landscape was recorded outside of Taivalkoski, Koillismaa, Finland using an Intenso Viddy, a cheap Video Messenger.The clip, 30 seconds in duration, of the landscape was transferred from the Viddy to a laptop. When played on the laptop the screen was filmed with t

5-HT-like immunoreactivity in the central nervous system of the crayfish Pacifastacus leniusculus

An immunocytochemical technique with the use of three different antibodies raised against serotonin was applied to localize the immunoreactive neurons in the central nervous system of the crayfish, Pacifastacus leniusculus. Immunoreactive neurons were found in three optic ganglia (medulla externa, interna and terminalis). They appeared in three layers of the medulla externa and interna. The medull

The compound eye of Leptodora kindtii (Cladocera): : An adaptation to planctonic life.

Each of the approximately 500 ommatidia in the compound eye of the cladoceran crustacean Leptodora kindtii has a crystalline cone consisting of five cells. Five retinula cells are also present, one of which contributes to the distal 1–2 μm of the rhabdom only; the other four retinula cells form a continuous rhabdom. Throughout the rhabdom its cross section displays two separate halves with the axi

The Origins and Myths of the Swedish Model of Workplace Democracy

In 1976 Sweden adopted a law on workplace democracy, presented by the Social Democratic government as the ‘reform of the century’. What can the reform tell us about the history of the Swedish Model and how it was revised during the early 1970s under the prime minister, Olof Palme? This article compares four grand narratives of the development of welfare states, viewing dominant narratives of the S

The flicker fusion frequency of budgerigars (Melopsittacus undulatus) revisited

While color vision and spatial resolution have been studied in many bird species, less is known about the temporal aspects of bird vision. High temporal resolution has been described in three species of passerines but it is unknown whether this is specific to passerines, to small actively flying birds, to insectivores or to birds living in bright habitats. Temporal resolution of vision is commonly

Active Site Mapping of an Aspartic Protease by Multiple Fragment Crystal Structures : Versatile Warheads to Address a Catalytic Dyad

Crystallography is frequently used as follow-up method to validate hits identified by biophysical screening cascades. The capacity of crystallography to directly screen fragment libraries is often underestimated, due to its supposed low-throughput and need for high-quality crystals. We applied crystallographic fragment screening to map the protein-binding site of the aspartic protease endothiapeps

Enhanced priming of old, not new soil carbon at elevated atmospheric CO2

Rising atmospheric CO2 concentrations accompanied by global warming and altered precipitation patterns calls for assessment of long-term effects of these global changes on carbon (C) dynamics in terrestrial ecosystems, as changes in net C exchange between soil and atmosphere will impact the atmospheric CO2 concentration profoundly. In many ecosystems, including the heath/grassland system studied h

Non-linearity in the impact of bankruptcy risk on leverage

The paper investigates the effect of bankruptcy risk on firms’ financing decisions. More specifically, we analyze if a higher probability of bankruptcy reduces incentives for debt financing due to an increase in expected bankruptcy cost. We argue that an increase in bankruptcy risk affects financial decisions only when the probability of bankruptcy is sufficiently high. We therefore model a nonlin

Colour reconnection - Models and tests

Recent progress on colour reconnection within the Pythia framework is presented. A new model is introduced, based on the SU(3) structure of QCD and a minimization of the potential string energy. The inclusion of the epsilon structure of SU(3) gives a new baryon production mechanism and makes it possible simultaneously to describe hyperon production at both e+e- and pp colliders. Finally, predictio

ATLAS LUCID detector upgrade for LHC Run 2

During the 2009-2013 data taking period (Run I) LUCID was successfully providing information about the luminosity delivered to ATLAS by the LHC. Starting from 2015 (Run II) the LHC machine is expected to provide about twice larger peak instantaneous luminosity and the bunch spacing in the machine is decreased by factor of two (from 50 ns to 25 ns). The original LU-CID design could not cope with th